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Wyniki wyszukiwania dla: MULTIFUNCTIONAL COMPOUND

  • JOURNAL OF ALLOYS AND COMPOUNDS

    Czasopisma

    ISSN: 0925-8388 , eISSN: 1873-4669

  • Multifunctional Materials

    Czasopisma

    eISSN: 2399-7532

  • Opioid Growth Factor and its Derivatives as Potential Non-toxic Multifunctional Anticancer and Analgesic Compounds

    Publikacja
    • J. Budka
    • S. Kowalski
    • M. Chylińska
    • K. Dzierzbicka
    • I. Inkielewicz-Stępniak

    - CURRENT MEDICINAL CHEMISTRY - Rok 2021

    In this paper, we review the structure-activity relationship of OGF and its analogues. We highlight also OGF derivatives with analgesic, immunomodulatory activity and the ability to penetrate the blood-brain barrier and may be used as safe agents enhancing chemotherapy efficacy and improving quality of life in cancer patients. The reviewed papers indicate that Met-enkephalin and its analogues are interesting candidates for the...

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  • Therapeutic Potential of Multifunctional Tacrine Analogues

    Publikacja

    - Current Neuropharmacology - Rok 2019

    Tacrine is a potent inhibitor of cholinesterases (acetylcholinesterase and butyrylcholinesterase) that shows limiting clinical application by liver toxicity. In spite of this, analogues of tacrine are considered as a model inhibitor of cholinesterases in the therapy of Alzheimer’s disease. The interest in these compounds is mainly related to a high variety of their structure and biological properties. In the present review, we...

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  • Safety-based approach in multifunctional building design

    Publikacja

    ABSTRACT: The modern trend in design of the public buildings is to create multifunctional environments in one building, hosting a variety of functions. Multifunctional buildings entertain large number of visitors. The complexity and vulnerability of this type of public space are the main reasons to use within their design process the performance based approach including the recognition of hazards. Safety and reliability approach...

  • Multifunctional PID Neuro-Controller for Synchronous Generator

    This paper deals with a PID Neuro-Controller (PIDNC) for synchronous generator system. The controller is based on artificial neural network and adaptive control strategy. It ensures two functions: maintaining the generator voltage at its desired value and damping electromechanical oscillations. The performance of the proposed controller is evaluated on the basis of simulation tests. A comparative study of the results obtained with...

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  • Therapeutic Potential of Multifunctional Derivatives of Cholinesterase Inhibitors

    Publikacja

    - Current Neuropharmacology - Rok 2021

    The aim of this work is review of tacrine analogues from the last three years, which were not included in the latest review work, donepezil and galantamine hybrids from 2015 and rivastigmine derivatives from 2014. In this account we summarize the efforts toward the development and characterization of non-toxic inhibitors of cholinesterases based on mentioned drugs with various interesting additional properties such as antioxidant,...

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  • Multifunctional Bandpass Filter/Displacement Sensor Component

    Publikacja

    This paper presents the design and realization of a multifunctional bandpassfilter/displacement-sensor using an edge-coupled microstrip bandpass filter loaded by a pair of split ring resonators (SRRs). It is shown that while the structure acts as a bandpass filter at its operating frequency, the phase of the reflection coefficient from a movable loading resonator at the resonance frequency of the resonator can be used for displacement...

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  • Multi-Criteria Approach in Multifunctional Building Design Process

    Publikacja

    - Rok 2017

    The paper presents new approach in multifunctional building design process. Publication defines problems related to the design of complex multifunctional buildings. Currently, contemporary urban areas are characterized by very intensive use of space. Today, buildings are being built bigger and contain more diverse functions to meet the needs of a large number of users in one capacity. The trends show the need for recognition of...

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  • Contemporary multifunctional buildings towards a sustainable development of the housing environment

    Development of contemporary urban centers depends on the basis that buildings present more and more complex structures in terms of size and purpose. They are referred to as multifunctional buildings. This aspiration has its origins in the development of urban centers and in the desire to optimize the built-up areas. The article presents the theory of the approach to the design of multifunctional buildings with a focus on the residential...

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