Wyniki wyszukiwania dla: ear pinna

• Epigenetic inhibitor zebularine activates ear pinna wound closure in the mouse

  Publikacja

  • P. Sass
  • P. Sosnowski
  • J. Podolak-Popinigis
  • B. Górnikiewicz
  • J. Kamińska
  • M. Deptuła
  • E. Nowicka
  • A. Wardowska
  • J. Ruczyński
  • P. Rekowski... i 12 innych

  - EBioMedicine - Rok 2019

  Background:Most studies on regenerative medicine focus on cell-based therapies and transplantations.Small-molecule therapeutics, though proved effective in different medical conditions, have not been extensivelyinvestigated in regenerative research. It is known that healing potential decreases with development and devel-opmental changes are driven by epigenetic mechanisms, which suggests epigenetic repression of regenerativecapacity.Methods:We...

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• Regenerative Drug Discovery Using Ear Pinna Punch Wound Model in Mice

  Publikacja

  • P. Sosnowski
  • P. Sass
  • P. Słonimska
  • R. Płatek
  • J. Kamińska
  • J. Baczyński-Keller
  • P. Mucha
  • G. Peszyńska-Sularz
  • A. Czupryn
  • M. Pikuła... i 5 innych

  - Pharmaceuticals - Rok 2022

  The ear pinna is a complex tissue consisting of the dermis, cartilage, muscles, vessels, and nerves. Ear pinna healing is a model of regeneration in mammals. In some mammals, including rabbits, punch wounds in the ear pinna close spontaneously; in common-use laboratory mice, they remain for life. Agents inducing ear pinna healing are potential regenerative drugs. We tested the effects of selected bioactive agents on 2 mm ear pinna...

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• WEAR

  Czasopisma

  ISSN: 0043-1648 , eISSN: 1873-2577

• Journal of the Civil War Era

  Czasopisma

  ISSN: 2154-4727 , eISSN: 2159-9807

• EAR AND HEARING

  Czasopisma

  ISSN: 0196-0202 , eISSN: 1538-4667

• Correlations between the wear of car brake friction materials and airborne wear particle emissions

  Publikacja

  • W. Tarasiuk
  • K. Golak
  • Y. Tsybrii
  • O. Nosko

  - WEAR - Rok 2020

  Airborne wear particles emitted from transport vehicle brakes are one of the main sources of toxic metals in inhalable particulate matter. Prediction of wear particle emissions may become more accurate if the relationship between the wear and particle emission characteristics is known. An experimental study was performed to investigate proportional correlations between the mass wear, 0.01–0.42 μm particle emission measured by a NanoScan...

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• Types of wear and tear of biomaterials used in orthopaedic surgery

  Publikacja

  • L. Klimek
  • E. Wołowiec
  • B. Majkowska-Marzec

  - Journal of Achievements in Materials and Manufacturing Engineering - Rok 2013

  Purpose of this paper is presentation of observations on different kinds of wear and tear of biomaterials used in contemporary orthopaedic surgery. Types of prosthesis damage, encountered in medical practice, and their causes have been described. Results of many clinical studies were analysed to review prosthesis damage from the stage of implanting (such as intrusion of a foreign object between its components) to their natural...

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• Odnawialne źródła enegi cy energetyka jądrowa- pinia społeczna

  Publikacja

  • N. Szewczuk-Krypa
  • M. Drosińska-Komor

  - Rok 2016

  W artykule zaprezentowano obecny stan i możliwości energii produkowanej z odnawianlych źródel energii (OŹE). W pracy przedstawiono uzasadnienie ekonomiczne oraz uwarunkowania środowiskowe dla wykorzystania konkretnych źródeł energii odnawialnej. Opinia wykreowana na podstawie przesłanek ekonomicznych i technicznych przeciwstawiona zostala opinii społecznej uzyskanej na podstawie ankiety. W artykule poruzsony został także temat...

• Effective density of airborne wear particles from car brake materials

  Publikacja

  • O. Nosko
  • U. Olofsson

  - JOURNAL OF AEROSOL SCIENCE - Rok 2017

  People living in urban environments are subject to high health risks due to various anthropogenic sources of airborne particulate matter, including wear of transport vehicle brakes. Studies of airborne particles often require an estimate of the effective particle density, a property that allows correct matching of mass and size characteristics measured by different aerosol instruments. In this study we investigated the effective...

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• Activation of endogenous regenerative potential in mammals using epigenetic inhibitor zebularine

  Publikacja

  • P. Sass

  - Rok 2021

  In this work, a nucleoside inhibitor of DNA methyltransferases, zebularine, was investigated as a wound healing and regeneration promoting agent. It was found that a high dose of intraperitoneally delivered zebularine improved punch wound closure in the ear pinna in mice. Both cytidine, a zebularine analogue, and uridine, a zebularine metabolite, did not promote ear pinna hole closure. The effect of zebularine on ear pinna healing...