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A novel method of creating thermoplastic chitosan blends to produce cell scaffolds by FDM additive manufacturing

Abstract

Due to its remarkable and promising biological and structural properties, chitosan has been widely studied in several potential applications in the biomedical sector. Attempts are being made to use this polymer and its properties in thermoplastics dedicated to 3D printing in FDM technology. However, chitosan can be processed only from acid solution, which limits its applications. The paper presents a new path for the production of filaments based on unstable chitosan hydrogel obtained by carbon dioxide saturation, as well as synthetic polymers such as polyvinyl alcohol and polycaprolactone. The results confirm that the absence of acid allows formation of thermally stable and printable filaments containing from 5% to 15% of chitosan, capable of reducing S. aureus and E. coli bacteria by 0.41–1.43 in logarithmic scale (56–94%) and 0.28–0.94 in logarithmic scale (36–89%), respectively.

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Category:
Articles
Type:
artykuły w czasopismach
Published in:
CARBOHYDRATE POLYMERS no. 280,
ISSN: 0144-8617
Language:
English
Publication year:
2022
Bibliographic description:
Tylingo R., Kempa P., Banach-Kopeć A., Mania S.: A novel method of creating thermoplastic chitosan blends to produce cell scaffolds by FDM additive manufacturing// CARBOHYDRATE POLYMERS -Vol. 280, (2022), s.119028-
DOI:
Digital Object Identifier (open in new tab) 10.1016/j.carbpol.2021.119028
Sources of funding:
  • Działalność statusowa
Verified by:
Gdańsk University of Technology

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