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The exposure to UV filters: Prevalence, effects, possible molecular mechanisms of action and interactions within mixtures

Abstract

Substances that can absorb sunlight and harmful UV radiation such as organic UV filters are widely used in cosmetics and other personal care products. Since humans use a wide variety of chemicals for multiple purposes it is common for UV filters to co-occur with other substances either in human originating specimens or in the environment. There is increasing interest in understanding such co-occurrence in form of potential synergy, antagonist, or additive effects of biological systems. This review focuses on the collection of data about the simultaneous occurrence of UV filters oxybenzone (OXYB), ethylexyl-methoxycinnamate (EMC) and 4-methylbenzylidene camphor (4-MBC) as well as other classes of chemicals (such as pesticides, bisphenols, and parabens) to understand better any such interactions considering synergy, additive effect and antagonism. Our analysis identified >20 different confirmed synergies in 11 papers involving 16 compounds.

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Authors (6)

  • Photo of  Alexandra Rafeletou

    Alexandra Rafeletou

    • Department of Surgical Sciences, Functional Pharmacology and Neuroscience, Uppsala University, Uppsala, Sweden
  • Photo of  Jenni Viivi Linnea Niemi

    Jenni Viivi Linnea Niemi

    • Department of Surgical Sciences, Functional Pharmacology and Neuroscience, Uppsala University, Uppsala, Sweden
  • Photo of  Francisco Alejandro Lagunas-Rangel

    Francisco Alejandro Lagunas-Rangel

    • Department of Surgical Sciences, Functional Pharmacology and Neuroscience, Uppsala University, Uppsala, Sweden
  • Photo of  Wen Liu

    Wen Liu

    • Department of Surgical Sciences, Functional Pharmacology and Neuroscience, Uppsala University, Uppsala, Sweden
  • Photo of  Helgi B. Schiöth

    Helgi B. Schiöth

    • Department of Surgical Sciences, Functional Pharmacology and Neuroscience, Uppsala University, Uppsala, Sweden

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Details

Category:
Articles
Type:
artykuły w czasopismach
Published in:
SCIENCE OF THE TOTAL ENVIRONMENT no. 928,
ISSN: 0048-9697
Language:
English
Publication year:
2024
Bibliographic description:
Rafeletou A., Niemi J. V. L., Lagunas-Rangel F. A., Liu W., Kudłak B., Schiöth H. B.: The exposure to UV filters: Prevalence, effects, possible molecular mechanisms of action and interactions within mixtures// SCIENCE OF THE TOTAL ENVIRONMENT -Vol. 928, (2024), s.170999-
DOI:
Digital Object Identifier (open in new tab) 10.1016/j.scitotenv.2024.170999
Sources of funding:
  • Statutory activity/subsidy
Verified by:
Gdańsk University of Technology

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