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Search results for: Breast and lung cancers
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High- and low-Molecular Weight oat Beta-Glucan Reveals Antitumor Activity in Human Epithelial Lung Cancer
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Oxidative DNA damage and antioxidant vitamin level: Comparison among lung cancer patients, healthy smokers and nonsmokers
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Neutrophilic Cathepsin C Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases
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Prognostic Value of TOP2A Gene Amplification and Chromosome 17 Polysomy in Early Breast Cancer
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Aggressive Phenotype of Cells Disseminated via Hematogenous and Lymphatic Route in Breast Cancer Patients
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Rapana thomasiana hemocyanin modified with ionic liquids with enhanced anti breast cancer activity
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Physical and psychological impairments of women with upper limb lymphedema following breast cancer treatment
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Nanosized zinc, epigenetic changes and its relationship with DMBA induced breast cancer in rats
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Sulforaphene, an isothiocyanate present in radish plants, inhibits proliferation of human breast cancer cells
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Plasma micronutrients, trace elements, and breast cancer in BRCA1 mutation carriers: an exploratory study
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Patient with metastatic breast cancer presenting as acute cholecystitis with one-year survival on hormonotherapy
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Physical activity, life satisfaction and adjustment to illness in women after treatment of breast cancer
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Effective kernel‐principal component analysis based approach for wisconsin breast cancer diagnosis
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Thyroid peroxidase (TPO) expressed in thyroid and breast tissues shows similar antigenic properties
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Expression of pendrin and NIS iodide transporters in human breast tumor and peri-tumoral tissue
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Analysis of transient thermal processes for improved visualization of breast cancer using IR imaging.
PublicationPrzedstawiono analizę możliwości i ograniczeń metod termograficznych w diagnostyce nowotworów piersi. Przeanalizowane termiczne modele numeryczne piersi z nowotworem pokazują, iż zastosowanie nowej metody aktywnej termografii dynamicznej z termicznym wymuszeniem zewnętrznym, może znacząco poprawić skuteczność wykrywania nowotworów piersi we wczesnym stadium ich rozwoju . Pokazano również wyniki badania klinicznego pacjentki...
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Adenylate kinase immobilized on graphene oxide impairs progression of human lung carcinoma epithelial cells through adenosinergic pathway
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Biological effects in photodynamic treatment combined with electropermeabilization in wild and drug resistant breast cancer cells
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A different methylation profile of circadian genes promoter in breast cancer patients according to clinicopathological features
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The effect of cabbage juice and its active components on transcription factor Nrf2 in breast cell lines
PublicationObniżenie zagrożenia chorobami nowotworowymi w przypadku diety bogatej w kapustę wiąże się ze zdolnością bioaktywnych związków tego warzywa do indukowania enzymów ochronnych 2. fazy będacych pod kontrolą czynnika transkrypcyjnego Nrf2. Zbadano wpływ soków z kapusty na poziom Nrf2 w komórkach unieśmiertelnionych i nowotworowych linii odpowiednio MCF10A i MCF-7. W obu przypadkach obserwowano wzrost poziomu tego czynnika oraz jego...
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Biochemical properties of thyroid peroxidase (TPO) expressed in human breast and mammary-derived cell lines
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Tuning of the Anti-Breast Cancer Activity of Betulinic Acid via Its Conversion to Ionic Liquids
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Increased plasma concentration of 4-pyridone-3-carboxamide-1-ß-D-ribonucleoside (4PYR) in lung cancer. Preliminary studies
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Polymeric micelle-mediated delivery of half-sandwich ruthenium(II) complexes with phosphanes derived from fluoroloquinolones for lung adenocarcinoma treatment
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C421 allele-specific ABCG2 gene amplification confers resistance to the antitumor triazoloacridone C-1305 in human lung cancer cells
PublicationGen ABCG2 charakteryzuje polimorficzność pozycji C341, która jest związana ze znacznym obniżeniem ekspresji tego genu i zdolności do transportu przez błonę komórkową. W pracy wykazaliśmy, że komórki raka płuc, które nabyły oporności na związek C-1305, zmieniły fenotyp z heterozygotycznego w odniesieniu do genu ABCG2 i wykazują amplifikację jedynie allelu C341 genu oraz zwiększoną zawartość mRNA i zmutowanego białka pompy ABCG2...
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Clinical and Biological Significance of ESR1 Gene Alteration and Estrogen Receptors Isoforms Expression in Breast Cancer Patients
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Therapy-Related Changes in the Serum Proteome Patterns of Early Stage Breast Cancer Patients with Different Outcomes
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Potential clinical application of serum proteome mass spectrometry analyses in breast cancer patients diagnosis and management
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Mass spectrometry-based serum proteome pattern analysis in molecular diagnostics of early stage breast cancer
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Occurrence of Breast Cancer in the Population of Peri- and Postmenopausal Women in the Aspect of Environmental Exposure to Airborne Dust Pollution
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Safe-by-Design Ligand-Coated ZnO Nanocrystals Engineered by an Organometallic Approach: Unique Physicochemical Properties and Low Toxicity toward Lung Cells
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Application of biocompatible and ultrastable superparamagnetic iron(iii) oxide nanoparticles doped with magnesium for efficient magnetic fluid hyperthermia in lung cancer cells
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c-Myc Protein Level Affected by Unsymmetrical Bisacridines Influences Apoptosis and Senescence Induced in HCT116 Colorectal and H460 Lung Cancer Cells
PublicationUnsymmetrical bisacridines (UAs) are highly active antitumor compounds. They contain in their structure the drugs previously synthesized in our Department: C-1311 and C-1748. UAs exhibit different properties than their monomer components. They do not intercalate to dsDNA but stabilize the G-quadruplex structures, particularly those of the MYC and KRAS genes. Since MYC and KRAS are often mutated and constitutively expressed in cancer...
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The Osteopontin Tissue Level as a Breast Cancer Biomarker in Females After Mastectomy Measured by the Capillary Gel Electrophoresis Technique
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Amplification of c-myc gene and overexpression of c-Myc protein in breast cancer and adjacent non-neoplastic tissue
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Prognostic Significance of ESR1 Amplification and ESR1 PvuII, CYP2C19*2, UGT2B15*2 Polymorphisms in Breast Cancer Patients
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918 The role of patients and doctors in making decisions about the choice of the kind of adjuvant treatment in early breast cancer
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2014 POSTER Serum proteome mass spectrometry analyses for identification of novel diagnostic biomarkers in breast cancer patients
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Presentation of Novel Architecture for Diagnosis and Identifying Breast Cancer Location Based on Ultrasound Images Using Machine Learning
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Determination of tocopherols and tocotrienols in human breast adipose tissue with the use of high performance liquid chromatography-fluorescence detection
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CYP19 mRNA and protein levels in nontumorogenic breast epithelial cells (MCF10A) treated with active components of cabbage juices
PublicationZbadano wpływ soków z kapusty na poziom ekspresji genu CYP19 w nietumorogennych komórkach nabłonka gruczołu mlekowego MCF10A kodującego enzym aromatazę uczestniczący w biosyntezie estrogenów i w związku z tym wpływający na zagrożenie rakiem piersi. Soki z kapusty oraz bioaktywne związki w nich występujące stosowane w niskich dawkach obniżały poziom ekspresji tego genu, a zatem miały działanie chemoprewencyjne. Wyższe dawki zarowno...
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Trastuzumab-Modified Gold Nanoparticles Labeled with 211At as a Prospective Tool for Local Treatment of HER2-Positive Breast Cancer
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Study of Bioreductive Anticancer Agent RH-1-Induced Signals Leading the Wild-Type p53-Bearing Lung Cancer A549 Cells to Apoptosis
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Utilizing Genome-Wide mRNA Profiling to Identify the Cytotoxic Chemotherapeutic Mechanism of Triazoloacridone C-1305 as Direct Microtubule Stabilization
PublicationRational drug design and in vitro pharmacology profiling constitute the gold standard in drug development pipelines. Problems arise, however, because this process is often dicult due to limited information regarding the complete identification of a molecule’s biological activities. The increasing aordability of genome-wide next-generation technologies now provides an excellent opportunity to understand a compound’s diverse eects...
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Mass spectrometry-based analysis of therapy-related changes in serum proteome patterns of patients with early-stage breast cancer
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Expression of stem cell and mesenchymal markers in circulating tumor cells is associated with poor prognosis of early breast cancer patients
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Influence of some anthropometric parameters on the risk of development of distal complications after mastectomy carried out because of breast carcinoma
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High-resolution synthesis of high-density breast mammograms: Application to improved fairness in deep learning based mass detection
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The effect of cabbage juice and it's active components on the protein level and expression of CYP19 in MCF-7 breast cancer cells
PublicationWiadomo, że bioaktywne skladniki kapusty mają chemoprewencyjne działanie w przypadku nowotworów piersi, między innymi ze względu na hamowanie aktywności enzymu aromatazy uczestniczącego w biosyntezie estrogenów. Badania prowadzono przy użyciu komórek raka piersi i stwierdzono, że soki z kapusty, zarówno pochodzącej z uprawy ekologicznej jak i przemysłowej, znacząco hamowały ekspresję genu CYP19 kodującego wspomniany enzym. Sugeruje...
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LC-PDA-MS and GC-MS Analysis of Scorzonera hispanica Seeds and Their Effects on Human Breast Cancer Cell Lines
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