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Search results for: targeted cancer therapy
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Relationship between Telomere Length, TERT Genetic Variability and TERT, TP53, SP1, MYC Gene Co-Expression in the Clinicopathological Profile of Breast Cancer
PublicationThe molecular mechanisms of telomerase reverse transcriptase (TERT) upregulation in breast cancer (BC) are complex. We compared genetic variability within TERT and telomere length with the clinical data of patients with BC. Additionally, we assessed the expression of the TERT, MYC, TP53 and SP1 genes in BC patients and in BC organoids (3D cell cultures obtained from breast cancer tissues). We observed the same correlation in the...
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Single nucleotide polymorphisms associated with papillary thyroid cancer
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Recognition Dynamics of Cancer Mutations on the ERp57-Tapasin Interface
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High-grade serous ovarian cancer: the clone wars
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Molecular diagnosis in type I epithelial ovarian cancer
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The Effects of Single Nucleotide Polymorphisms in Cancer RNAi Therapies
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Coping strategies and sexual satisfaction in bladder cancer males
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Circadian Gene Polymorphisms Associated with Breast Cancer Susceptibility
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Novel Inhibitor-Based Therapies for Thyroid Cancer—An Update
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Neural network breast cancer relapse time prognosis
PublicationPrzedstawiono architekturę i wyniki testowania sztucznej sieci neuronowej w prognozowaniu czasu nawrotu choroby u kobiet chorych na raka piersi. Sieć neuronowa uczona była na danych zgromadzonych przez 20 lat. Dane opisują grupę 439 pacjentów za pomocą 40 parametrów. Spośród tych parametrów wybrano 6 najistotniejszych: liczbę przerzutowych węzłów chłonnych, wielkość guza, wiek, skalę według Blooma oraz stan receptorów estrogenowych...
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Antimicrobial photodynamic therapy with fulleropyrrolidine: photoinactivation mechanism of Staphylococcus aureus, in vitro and in vivo studies
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Murine Model Imitating Chronic Wound Infections for Evaluation of Antimicrobial Photodynamic Therapy Efficacy
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Combination of therapy with 5-fluorouracil and cisplatin with electroporation in human ovarian carcinoma model in vitro
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Biological and psychological components of depression in patients receiving IFN-alpha therapy for hepatitis C
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Clot Lysis Time Predicts Stroke During Anticoagulant Therapy in Patients with Atrial Fibrillation
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Adoptive Cell Therapy—Harnessing Antigen-Specific T Cells to Target Solid Tumours
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Surface Modification of Nanocrystalline TiO2 Materials with Sulfonated Porphyrins for Visible Light Antimicrobial Therapy
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Beta‐blockers as sub‐optimal treatment for hypertension: Time for first‐line therapy revision?
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Use of optical skin phantoms for preclinical evaluation of laser efficiency for skin lesion therapy
PublicationSkin lesions are commonly treated using laser heating. However, the introduction of new devices into clinical practice requires evaluation of their performance. This study presents the application of optical phantoms for assessment of a newly developed 975-nm pulsed diode laser system for dermatological purposes. Such phantoms closely mimic the absorption and scattering of real human skin (although not precisely in relation to...
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Cancer stem cells in drug resistance and drug screening: can we exploit the cancer stem cell paradigm in search for new antitumor agents?
PublicationPraca przedstawia przegląd literatury dotyczącej hipotezy komórek pierwotnych nowotworu, w szczególności w ich oporności na istniejące terapie. Dyskutowane jest także zagadnienie możliwości wykorzystania wiedzy o tych komórkach do konstrukcji nowych testów do badań przesiewowych in vitro w celu poszukiwania nowych leków przeciwnowotworowych.
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Prospective assessment of continuous subcutaneous insulin infusion therapy in young children with type 1 diabetes
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T-House. Shaping Ergonomic and Flexible Interiors in Modular Form Connected to Horticultural Therapy Zone
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POEMS Syndrome: Real World Experience in Diagnosis and Systemic Therapy - 108 Patients Multicenter Analysis
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Cardiovascular risk and response to lipid lowering therapy in patients with HIV infection according to different recommendations
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Efficacy of the Whole-Body Cryotherapy as Add-on Therapy to Pharmacological Treatment of Depression—A Randomized Controlled Trial
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The impact of an electronic monitoring and reminder device on patient compliance with antihypertensive therapy: a randomized controlled trial
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Add‐on therapy with doxazosin in patients with hypertension influences arterial stiffness and albuterol‐mediated arterial vasodilation
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Enhanced susceptibility of SARS-CoV-2 spike RBD protein assay targeted by cellular receptors ACE2 and CD147: Multivariate data analysis of multisine impedimetric response
PublicationSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enters the cells through the binding of spike protein to the host cell surface-expressing angiotensin-converting enzyme 2 (ACE2) or by endocytosis mediated by extracellular matrix metalloproteinase inducer (CD147). We present extended statistical studies of the multisine dynamic electrochemical impedance spectroscopy (DEIS) revealing interactions between Spike RBD and...
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Sulforaphane inhibits growth of phenotypically different breast cancer cells
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Biological Effects of Cold Atmospheric Pressure Plasma on Skin Cancer
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Clinical Relevance of Circulating Tumor Cells in Prostate Cancer Management
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Nuclear quantum effects in a HIV/cancer inhibitor: The case of ellipticine
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Pemphigus foliaceus in a patient with skin cancer with metastases to lymph nodes
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Analysis of 5-Methylcytosine in DNA of Breast and Colon Cancer Tissues
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C-reactive Protein as a Diagnostic and Prognostic Factor of Endometrial Cancer
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The effects of RNA editing in cancer tissue at different stages in carcinogenesis
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Bladder cancer detection using a peptide substrate of the 20S proteasome
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Extracellular miRNAs as Biomarkers of Head and Neck Cancer Progression and Metastasis
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C-reactive protein as a diagnostic and prognostic factor of endometrial cancer
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Metabolic profiling of pteridines for determination of potential biomarkers in cancer diseases
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Comparison of Pteridine Normalization Methods in Urine for Detection of Bladder Cancer
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Notch signalling pathway as an oncogenic factor involved in cancer development
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The role of Snail1 transcription factor in colorectal cancer progression and metastasis
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Common variants of xeroderma pigmentosum genes and prostate cancer risk
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The ICTBioMed NCIP Hub: Cancer research in a science gateway consortium
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The Role of miRNA-7 in the Biology of Cancer and Modulation of Drug Resistance
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Synthesis, molecular structure, and metabolic stability of new series of N' -(2-alkylthio-4-chloro-5-methylbenzenesulfonyl)-1-(5-phenyl-1 H -pyrazol-1-yl)amidine as potential anti-cancer agents
PublicationA series of new N'-(2-alkylthio-4-chloro-5-methylbenzenesulfonyl)-1-(5-phenyl-1H-pyrazol-1-yl)amidine derivatives have been synthesized and evaluated in vitro by MTT assays for their antiproliferative activity against cell lines of colon cancer HCT-116, cervical cancer HeLa and breast cancer MCF-7. The studied compounds display selective activity mainly against HCT-116 and HeLa cells. Thus, five compounds show selective cytotoxic...
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Australian Occupational Therapy Journal
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British Journal of Occupational Therapy
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British Journal of Music Therapy
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