Search results for: MUTATION DETECTION

• Astrocytoma, NOS - Unknown, 41 - Tissue image [3300730069391171]

  Open Research Data

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BRAIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Astrocytoma, NOS - Unknown, 41 - Tissue image [3301001549114131]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BRAIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• High grade serous carcinoma - Female, 34 - Tissue image [8310729566967371]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of OVARY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Astrocytoma, NOS - Unknown, 41 - Tissue image [3300730069392001]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BRAIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Glioblastoma, NOS - Unknown, 33 - Tissue image [3290730016642701]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BRAIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Glioblastoma, NOS - Unknown, 33 - Tissue image [3290730016648091]

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  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BRAIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Astrocytoma, NOS - Unknown, 41 - Tissue image [3300730069393431]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BRAIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Waldenstrom macroglobulinemia - Female, 50 - Tissue image [11290630017293601]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Waldenstrom macroglobulinemia - Female, 50 - Tissue image [3300730069459481]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Waldenstrom macroglobulinemia - Female, 50 - Tissue image [3300730069453581]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Glioblastoma, NOS - Unknown, 33 - Tissue image [3290730016646091]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BRAIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Primary myelofibrosis - Male, 66 - Tissue image [1129063001729151]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Glioblastoma, NOS - Unknown, 33 - Tissue image [3290730016649081]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BRAIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Glioblastoma, NOS - Unknown, 33 - Tissue image [3290730016643591]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BRAIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Astrocytoma, NOS - Unknown, 41 - Tissue image [3300730069393551]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BRAIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Astrocytoma, NOS - Unknown, 41 - Tissue image [3300730069398071]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BRAIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• COVID‐19: A systematic review and update on prevention, diagnosis, and treatment

  Publication

  • H. Aghamirza Moghim Aliabadi
  • R. Eivazzadeh‐Keihan
  • A. Beig Parikhani
  • S. Fattahi Mehraban
  • A. Maleki
  • S. Fereshteh
  • M. Bazaz
  • A. Zolriasatein
  • B. Bozorgnia
  • S. Rahmati... and 11 others

  - MedComm - Year 2022

  Since the rapid onset of the COVID-19 or SARS-CoV-2 pandemic in the world in 2019, extensive studies have been conducted to unveil the behavior and emission pattern of the virus in order to determine the best ways to diagnosis of virus and thereof formulate effective drugs or vaccines to combat the disease. The emergence of novel diagnostic and therapeutic techniques considering the multiplicity of reports from one side and contradictions...

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• Waldenstrom macroglobulinemia - Female, 50 - Tissue image [11290630017292111]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Waldenstrom macroglobulinemia - Female, 50 - Tissue image [3300730069457891]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Waldenstrom macroglobulinemia - Female, 50 - Tissue image [11290630017294351]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Waldenstrom macroglobulinemia - Female, 50 - Tissue image [11290630017294051]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Waldenstrom macroglobulinemia - Female, 50 - Tissue image [11290630017297561]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Glioblastoma, NOS - Unknown, 33 - Tissue image [3290730016643601]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BRAIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Waldenstrom macroglobulinemia - Female, 50 - Tissue image [11290630017293021]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Primary myelofibrosis - Male, 66 - Tissue image [11290630017293981]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Waldenstrom macroglobulinemia - Female, 50 - Tissue image [11290630017296721]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Waldenstrom macroglobulinemia - Female, 50 - Tissue image [11290630017291451]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Comprehensive Evaluation of the Biological Properties of Surface-Modified Titanium Alloy Implants

  Publication

  • P. Piszczek
  • A. Radtke
  • M. Ehlert
  • T. Jędrzejewski
  • A. Sznarkowska
  • B. Sadowska
  • M. Bartmański
  • Y. K. Erdogan
  • B. Ercan
  • W. Jędrzejczyk

  - Journal of Clinical Medicine - Year 2020

  An increasing interest in the fabrication of implants made of titanium and its alloys results from their capacity to be integrated into the bone system. This integration is facilitated by different modifications of the implant surface. Here, we assessed the bioactivity of amorphous titania nanoporous and nanotubular coatings (TNTs), produced by electrochemical oxidation of Ti6Al4V orthopedic implants’ surface. The chemical composition...

  Full text available to download

• Essential thrombocythemia - Female, 68 - Tissue image [11290630017295411]

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  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Essential thrombocythemia - Female, 68 - Tissue image [11290630017291241]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Essential thrombocythemia - Female, 68 - Tissue image [11290630017294601]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Waldenstrom macroglobulinemia - Female, 50 - Tissue image [11290630017299501]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Waldenstrom macroglobulinemia - Female, 50 - Tissue image [11290630017291461]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Waldenstrom macroglobulinemia - Female, 50 - Tissue image [11290630017282841]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Primary myelofibrosis - Male, 66 - Tissue image [1129063001729431]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Primary myelofibrosis - Male, 66 - Tissue image [11290630017293921]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Two small RNAs conserved in Enterobacteriaceae provide intrinsic resistance to antibiotics targeting the cell wall biosynthesis enzyme glucosamine-6-phosphate synthase

  Publication

  • M. Khan
  • Y. Gopel
  • S. Milewski
  • B. Gorke

  - Frontiers in Microbiology - Year 2016

  Formation of glucosamine-6-phosphate GlcN6P) by enzyme GlcN6P synthase (GlmS) represents the first step in bacterial cell envelope synthesis. In Escherichia coli, expression of glmS is controlled by small RNAs (sRNAs) GlmY and GlmZ. GlmZ activates the glmS mRNA by base-pairing. When not required, GlmZ is bound by adapter protein RapZ and recruited to cleavage by RNase E inactivating the sRNA. The homologous sRNA GlmY activates...

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• Molecular differences in mitochondrial DNA (mtDNA) genomes of dogs with malignant mammary tumours

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  open access

  • B. Ślaska
  • K. Kowal
  • A. Tkaczyk-Wlizło
  • M. Pierzchała
  • J. Gawor

  The aim of this study was to determine molecular defects in mitochondrial DNA with the use of large-scale genome analysis in malignant canine mammary gland tumours and indicate whether these changes were linked with the carcinogenesis process. With the use of the NGS technology, we sequenced 27 samples of mtDNA isolated from blood and tumours obtained...

• Suspended-sediment transport related to ice-cover conditions during cold and warm winters, Toudaoguai stretch of the Yellow River, Inner Mongolia, China

  Publication

  • S. Zhao
  • Q. Zhou
  • W. Wang
  • Y. Wu
  • C. Lin
  • Q. Quan
  • P. Radan
  • Y. Tuo
  • T. Kolerski

  - ECOLOGICAL INDICATORS - Year 2023

  The presence of winter ice in cold regions changes the water level, flow rate, velocity distribution, and other parameters of the river, which in turn affects the sediment concentration and channel evolution. Based on data obtained from Toudaoguai Hydrological Station from 1959 to 2021, this study examines the characteristics of the ice regime during cold and warm winters and the water and sediment transport processes along the...

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• Virulence, antifungal susceptibility and molecular mechanisms of echinocandin resistance among Candida isolates recovered from clinical specimens

  Publication

  • M. Mroczyńska-Szeląg

  - Year 2020

  Fungi of the genus Candida belong to the natural microflora of healthy individuals. However, they can also be a cause of opportunistic infections especially among patients with an impaired immune system. The first line therapy of Candida infections is based on triazoles. However, in recent years there an increase of azole resistant Candida spp., in particular C. glabrata and C. krusei, has been observed. For this reason, echinocandin...

• Regulation of LPS assembly via controlled proteolysis and sensing of LPS stress in Escherichia coli

  Publication

  • D. Biernacka

  - Year 2022

  Lipopolysaccharide (LPS) is a complex glycolipid, essential for the bacterial viability and along with phospholipids, it constitutes the major amphiphilic component of outer membrane (OM) in most of the Gram-negative bacteria, including Escherichia coli. LPS molecules confer an effective permeability barrier to the OM and play a crucial role in bacteria-environment and -host interactions. The synthesis and accumulation of this...

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• Genome-Wide DNA Methylation and Gene Expression in Patients with Indolent Systemic Mastocytosis

  Publication

  • A. Górska
  • M. Urbanowicz
  • Ł. Grochowalski
  • M. Seweryn
  • M. Sobalska-Kwapis
  • T. K. Wojdacz
  • M. Lange
  • M. Gruchała-Niedoszytko
  • J. Jarczak
  • D. Strapagiel... and 6 others

  - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - Year 2023

  Mastocytosis is a clinically heterogenous, usually acquired disease of the mast cells with a survival time that depends on the time of onset. It ranges from skin-limited to systemic disease, including indolent and more aggressive variants. The presence of the oncogenic KIT p. D816V gene somatic mutation is a crucial element in the pathogenesis. However, further epigenetic regulation may also affect the expression of genes that...

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• Zastosowanie immobilizowanego białka MutS do wychwytywania fragmentów DNA zawierających niesparowane zasady

  Publication

  • M. Banasik

  - Year 2017

  Białko MutS wiąże DNA zawierające błędnie sparowane oraz niesparowane zasady w DNA. Podjęto szereg prób wykorzystania tego białka jako narzędzia do detekcji nieznanych mutacji lub zagęszczania frakcji DNA z niesparowaną zasadą. Dotychczas żadna z metod oparta na użyciu białka MutS nie została wdrożona powszechnie do praktyki laboratoryjnej. Głównym powodem takiego stanu rzeczy jest stosunkowo silne powinowactwo MutS do DNA w pełni...