Filters
total: 488
-
Catalog
- Publications 271 available results
- Journals 16 available results
- Publishing Houses 1 available results
- People 7 available results
- Inventions 8 available results
- Projects 8 available results
- Research Teams 1 available results
- e-Learning Courses 57 available results
- Open Research Data 119 available results
Search results for: SAC
-
Transcriptional activity of epigenetic remodeling genes declines in keratinocytes after in vitro expansion
PublicationPURPOSE: In vitro expansion is an invaluable method to obtain keratinocytes in amounts necessary for effective transplantation therapies. In vitro cell culturing provokes questions concerning potential epigenetic alterations occurring in expanded cells in the context of usefulness for transplantation and safety. The purpose of this study was to investigate as to whether keratinocyte expansion is associated with changes in the activity...
-
Neotenic phenomenon in gene expression in the skin of Foxn1- deficient (nude) mice - a projection for regenerative skin wound healing
PublicationMouse fetuses up to 16 day of embryonic development and nude (Foxn1- deficient) mice are examples of animals that undergo regenerative (scar-free) skin healing. The expression of transcription factor Foxn1 in the epidermis of mouse fetuses begins at embryonic day 16.5 which coincides with the transition point from scar-free to scar-forming skin wound healing. In the present study, we tested the hypothesis that Foxn1 expression...
-
Naturally occurring mitochondrial DNA heteroplasmy in the MRL mouse
PublicationThe MRL/MpJ mouse is an inbred laboratory strain of Mus musculus, known to exhibit enhanced autoimmunity, increased wound healing, and increased regeneration properties. We report the full-length mitochondrial DNA (mtDNA) sequence of the MRL mouse (Accession # EU450583), and characterize the discovery of two naturally occurring heteroplasmic sites. The first is a T3900C substitution in the TpsiCloop of the tRNA methionine gene...
-
Oxidative modification induced by photodynamic therapy with Photofrin®II and 2-methoxyestradiol in human ovarian clear carcinoma (OvBH-1) and human breast adenocarcinoma (MCF-7) cells
Publication -
Sex contribution to average age at onset of Huntington's disease depends on the number of (CAG)n repeats
PublicationHuntington’s disease (HD) is a hereditary neurodegenerative disorder caused by the extension of the CAG repeats in exon 1 of the HTT gene and is transmitted in a dominant manner. The present study aimed to assess whether patients’ sex, in the context of mutated and normal allele length, contributes to age on onset (AO) of HD. The study population comprised a large cohort of 3723 HD patients from the European Huntington’s Disease...
-
Circulating miRNA profiles and the risk of hemorrhagic transformation after thrombolytic treatment of acute ischemic stroke: a pilot study
PublicationBackground: Hemorrhagic transformation (HT) in acute ischemic stroke is likely to occur in patients treated with intravenous thrombolysis (IVT) and may lead to neurological deterioration and symptomatic intracranial hemorrhage (sICH). Despite the complex inclusion and exclusion criteria for IVT and some useful tools to stratify HT risk, sICH still occurs in approximately 6% of patients because some of the risk factors for this...
-
Analiza i przetwarzanie sygnałów telekomunikacyjnych (zima 2023/24)
e-Learning Courses -
Functional Interfaces, Biological Pathways, and Regulations of Interferon-Related DNA Damage Resistance Signature (IRDS) Genes
Publication -
Photodynamic therapy – mechanisms, photosensitizers and combinations
Publication -
Combination of therapy with 5-fluorouracil and cisplatin with electroporation in human ovarian carcinoma model in vitro
Publication -
The photodynamic effect of far-red range phthalocyanines (AlPc and Pc green) supported by electropermeabilization in human gastric adenocarcinoma cells of sensitive and resistant type
Publication -
Folate/homocysteine metabolism and lung cancer risk among smokers
PublicationBackground: Folate and homocysteine are involved in DNA synthesis and methylation processes, which are deregulated during carcinogenesis. Objectives: The aim of this study was to assess the relationship between folate/homocysteine concentrations, the functional polymorphisms of folate/homocysteine genes and lung cancer risk among cigarette smokers. Study design: The study included 132 lung cancer patients and 396 controls from...
-
Coincidence of PTPN22 c.1858CC and FCRL3 -169CC genotypes as a biomarker of preserved residual β-cell function in children with type 1 diabetes
Publication -
Advancements in the Additive Manufacturing of Magnesium and Aluminum Alloys through Laser-Based Approach
PublicationComplex structures can now be manufactured easily utilizing AM technologies to meet the pre-requisite objectives such as reduced part numbers, greater functionality, and lightweight, among others. Polymers, metals, and ceramics are the few materials that can be used in AM technology, but metallic materials (Magnesium and Aluminum) are attracting more attention from the research and industrial point of view. Understanding the role...
-
Association of Genes Related to Oxidative Stress with the Extent of Coronary Atherosclerosis
PublicationOxidative stress is believed to play a critical role in atherosclerosis initiation and progression. In line with this, in a group of 1099 subjects, we determined eight single nucleotide polymorphisms (SNPs) related to oxidative stress (PON1 c.575A>G, MPO c.463G>A, SOD2 c.47T>C, GCLM c.590C>T, NOS3 c.894G>T, NOS3 c.786T>C, CYBA c.214C>T, and CYBA c.932A>G) and assessed the extent of atherosclerosis in coronary arteries based on...
-
Examination of epigenetic inhibitor zebularine in treatment of skin wounds in healthy and diabetic mice
PublicationDNA methyltransferase inhibitor zebularine was proven to induce regeneration in the ear pinna in mice. We utilized a dorsal skin wound model to further evaluate this epigenetic inhibitor in wound healing. Full-thickness excisional wounds were made on the dorsum of 2 and 10-month-old healthy BALB/c and 3 and 8-month-old diabetic (db/db) mice, followed by topical or intraperitoneal zebularine delivery. Depending on the strain, age,...
-
Total impact of oxidative stress genes on cardiovascular events—a 7-year follow-up study
PublicationCardiovascular (CV) events are the number one cause of lifetime disability and deaths worldwide. It is well known that traditional risk factors do not fully correlate with clinical outcomes; therefore, searching for other markers that would explain CV events occurrence seems essential. Of importance, one of the main factors at the origin of CV events is oxidative stress, causing inflammation and atherosclerotic plaque instability....
-
ELECTROCHEMOTHERAPY COMBINED WITH STANDARD AND CO2 LASER SURGERIES IN CANINE ORAL MELANOMA
Publication -
The effects of p53 gene inactivation on mutant proteome expression in a human melanoma cell model
Publication -
Autoimmunity and Cancer—Two Sides of the Same Coin
Publication -
Analiza i przetwarzanie sygnałów telekomunikacyjnych (zima 2022/23)
e-Learning CoursesElektronika i Telekomunikacja, studia inżynierskie sem. 7
-
Podstawy systemów informacyjnych - 2023/24
e-Learning CoursesKurs e-nauczania przeznaczony na potrzeby przedmiotu "Podstawy systemów informacyjnych" realizowanego na kierunku Elektronika i Telekomunikacja, studia inżynierskie sem. 5
-
Podstawy systemów informacyjnych - 2022/23
e-Learning CoursesElektronika i Telekomunikacja, studia inżynierskie sem. 5
-
Techniki transmisji i komutacji - wykład 2022/23
e-Learning Courses -
Techniki transmisji i komutacji - wykład 2023/24
e-Learning Courses -
MACH_ Maszynoznawstwo i Aparatura Chemiczna - 2022
e-Learning Courses -
Maszynoznawstwo i Aparatura Chemiczna -2024
e-Learning Courses -
Maszynoznawstwo i Aparatura Chemiczna
e-Learning Courses -
Maszynoznawstwo i Aparatura Chemiczna -2024 !
e-Learning Courses -
NADPH Oxidase Gene Polymorphism is Associated with Mortality and Cardiovascular Events in 7-Year Follow-Up
PublicationThe CYBA gene encodes the regulatory subunit of NADPH oxidase, which maintains the redox state within cells and in the blood vessels. That led us to investigate the course of coronary artery disease (CAD) with regards to CYBA polymorphisms. Thus, we recruited 1197 subjects with coronary atherosclerosis and observed them during 7-year follow-up. Three CYBA polymorphisms: c.214C>T (rs4673), c.-932G>A (rs9932581), and c.*24G>A (1049255)...
-
Plasma free amino acid profiling as metabolomic diagnostic and prognostic biomarker in paediatric cancer patients: a follow‑up study
PublicationAmino acids (AAs) play a crucial role in cancer cell metabolism. Levels of 22 plasma AAs at the time of diagnosis and after treatment were established among 39 pediatric cancer patients and 33 healthy children. Glutamic acid levels decreased and tryptophan levels increased during treatment. Cancer patients presented significantly lower levels of glutamine and leucine post-treatment while levels of 12 other AAs were higher comparing...
-
Evidence for sex differences in the determinants of homocysteine concentrations
Publication -
In Search of Panacea—Review of Recent Studies Concerning Nature-Derived Anticancer Agents
Publication -
Genetyka człowieka 22.05 3h
e-Learning CoursesWykłady z genetyki człowieka, odrobienie wykładów zaległych z 12.03, 19.03 i 2.04.
-
Genetyka człowieka - wykład 14.05.2020
e-Learning CoursesKolejny wykład z genetyki człowieka
-
Genetyka człowieka - wykład 7.05.2020
e-Learning CoursesKolejny wykład z genetyki człowieka.
-
Genetyka człowieka wykład 28.05.2020
e-Learning CoursesKolejny wykład z genetyki człowieka w formie webinarium.
-
Inżynieria genetyczna wykład 5.05.2020 15.15
e-Learning CoursesKolejny wykład z inżynierii genetycznej
-
Inżynieria genetyczna wykład 9.06.2020
e-Learning CoursesKolejny wyklad zdalny z inżynierii genetycznej w postaci webinarium.
-
Genetyka człowieka - TEST 14.06.2021
e-Learning CoursesTest zaliczeniowy z genetyki człowieka 14.06.2021
-
INGEN EXAM 18.06.2021 12.00
e-Learning CoursesEgzamin zdalny z inżynierii genetycznej 18.06.2021 12.00
-
Inżynieria genetyczna wykład 2.06.2020
e-Learning CoursesKolejny wyklad zdalny z inżynierii genetycznej w postaci webinarium.
-
Environmental biology
e-Learning CoursesLecture on Environmental Biology
-
Inżynieria genetyczna - wykład 12.05.2020 12.15
e-Learning CoursesKolejny wykład z inżynierii genetycznej
-
Environmental biology exam
e-Learning Courses -
Inżynieria genetyczna wykład 19.05.2020 12.15
e-Learning CoursesKolejny wykład z inżynierii genetycznej.
-
Genetyka czlowieka wykład 21.05.2020
e-Learning CoursesKolejny wykład z genetyki człowieka
-
Retained features of embryonic metabolism in the adult MRL mouse
PublicationThe MRL mouse is an inbred laboratory strain that was derived by selective breeding in 1960 from the rapidly growing LG/J (Large) strain. MRL mice grow to nearly twice the size of other commonly used mouse strains, display uncommonly robust healing and regeneration properties, and express later onset autoimmune traits similar to Systemic Lupus Erythematosis. The regeneration trait (heal) in the MRL mouse maps to 14-20 quantitative...
-
Comparison of different digestion methods for proteomic analysis of isolated cells and FFPE tissue samples
Publication -
Transcriptional profile of in vitro expanded human epidermal progenitor cells for the treatment of non-healing wounds
PublicationBackground Epidermal progenitor cells (EPCs) have been under extensive investigation due to their increasing potential of application in medicine and biotechnology. Cultured human EPCs are used in the treatment of chronic wounds and have recently became a target for gene therapy and toxicological studies. One of the challenges in EPCs culture is to provide a high number of undifferentiated, progenitor cells displaying high viability...