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Search results for: adipokines, cytokines, adrenal tumors
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Adipokine and cytokine levels in non-functioning adrenal incidentalomas (NFAI)
PublicationDue to the fact that overweight or obesity is accompanied by hormonally active adrenal tumors: Cushing Syndrome-(CS) and Subclinical Cushing Syndrome (SCS), it is of high interest the correlation between different adipokines and cytokines secreted by adipose tissue, with metabolic disorders and hormonal activity in this group. Even in non-functioning adrenal incidentalomas (NFAI) elevated risk for cardiovascular disease and metabolic...
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Adipokine and cytokine levels in patients with adrenocortical cancer, subclinical Cushing's syndrome and healthy controls
PublicationIntroduction In recent years researchers have focused at hormonal activity in Cushing’s syndrome (CS) in connection with metabolic disorders and the role of adipokines and cytokines secreted by the adipose tissue. The aim of the study was to investigate levels of adipokines and cytokines in patients with: subclinical CS (SCS) – in relation to hormonal parameters of hypercortisolemia, and, adrenocortical cancer (ACC). Materials...
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Wilms’ tumour-the reality of tissue analysis in the Polish Paediatric Solid Tumours Group
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Identification of High-Risk Stage II Colorectal Tumors by Combined Analysis of the NDRG1 Gene Expression and the Depth of Tumor Invasion
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Adrenal Secretory Protease
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Expression of pendrin and NIS iodide transporters in human breast tumor and peri-tumoral tissue
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Changes in the Secretion of Melatonin and Selected Adipokines during the Progression of Parkinson’s Disease—Preliminary Studies
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Coordinated reprogramming of renal cancer transcriptome, metabolome and secretome associates with immune tumor infiltration
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Enhancing Renal Tumor Detection: Leveraging Artificial Neural Networks in Computed Tomography Analysis
PublicationRenal cell carcinoma is one of the most common cancers in Europe, with a total incidence rate of 18.4 cases per 100 000 population. There is currently significant overdiagnosis (11% to 30.9%) at times of planned surgery based on radiological studies. The purpose of this study was to create an artificial neural network (ANN) solution based on computed tomography (CT) images as an additional tool to improve the differentiation of...
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Melatonin Supplementation Lowers Oxidative Stress and Regulates Adipokines in Obese Patients on a Calorie-Restricted Diet
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CRH functions as a growth factor/cytokine in the skin
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The Role of Inflammatory Cytokines in the Pathogenesis of Colorectal Carcinoma-Recent Findings and Review
PublicationThe inflammatory process plays a significant role in the development of colon cancer (CRC). Intestinal cytokine networks are critical mediators of tissue homeostasis and inflammation but also impact carcinogenesis at all stages of the disease. Recent studies suggest that inflammation is of greater importance in the serrated pathway than in the adenoma-carcinoma pathway. Interleukins have gained the most attention due to their...
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The Role of Inflammatory Cytokines in the Pathogenesis of Colorectal Carcinoma—Recent Findings and Review
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The influence of new MDP and tuftsin analogs on cytokines levels in experimentally induced sepsis
PublicationPrzedstawiono wpływ analogów MDP z tuftsyną na poziom cytokin: TNF(alfa), IL6, IL10, INF(gamma). Wszystkie badane związki działały aktywująco na makrofagi narządowe i niezwykle efektywnie na monocyty krwi obwodowej. Na podstawie otrzymanych wyników można stwierdzić, że badane związki są za słabe by mogły działać jako samodzielne terapeutyki. ich zastosowanie w klinice upatruje się raczej w formie adjuwantów.
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Evaluation of survivin splice variants in pituitary tumors
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Distinct Cytokine Patterns in Different States of Kidney Allograft Function
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Aggregated neutrophil extracellular traps resolve inflammation by proteolysis of cytokines and chemokines and protection from antiproteases
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The cytokine profile of mature milk from smoking and non-smoking mothers
PublicationZweryfikowano wpływ palenia kobiet na poziom cytokin (IL-1α, IL-1β, IL-6, IL-8, IL-10 i TNF-α) w mleku ludzkim w 30-32 dni po porodzie. Badana grupa składała się z 24 kobiet po porodzie, które deklarowały palenie więcej niż pięciu papierosów dziennie. Grupę kontrolną stanowiło 45 niepalących kobiet. W porównaniu do kobiet niepalących w mleku kobiet palących stwierdzono znacznie wyższe stężenia cytokiny IL-1α (P = 0,04). Nie stwierdzono...
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Metastasis of the testicular germ cell tumors to the parotid gland
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Zinc and the Innovative Zinc-α2-Glycoprotein Adipokine Play an Important Role in Lipid Metabolism: A Critical Review
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The impact of prenatal stress on insulin-like growth factor-1 and pro-inflammatory cytokine expression in the brains of adult male rats: The possible role of suppressors of cytokine signaling proteins
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Genetic diversity of Legionella pcs and pmtA genes and the effect of utilization of choline by Legionella spp. on induction of proinflammatory cytokines
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Diagnosis of Brain Tumors Through Global Specific DNA Methylation Analysis
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Baseline chromogranin A and its dynamics are prognostic markers in gastroenteropancreatic neuroendocrine tumors
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Bariatric surgery and incidental gastrointestinal stromal tumors – a single-center study
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TLC-based detection of methylated cytosine: application to aging epigenetics
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Cytokine IL6, but not IL-1β, TNF-α and NF-κB is increased in paediatric cancer patients
PublicationCytokines are responsible for maintaining homeostasis as cell growth, differentiation, migration and apoptosis mediators. They play a pivotal role in immune responses to inflammatory reactions. In oncological diseases, the cross-talk between cells of the immunological system and cells of the tumour microenvironment is led by cytokines. Also, the overproduction of cytokines may change the tumour microenvironment and stimulate tumour...
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Rapid PD-L1 detection in tumors with PET using a highly specific peptide
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Chemometric Evaluation of Urinary Steroid Hormone Levels as Potential Biomarkers of Neuroendocrine Tumors
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Molecular Characterization of Growth Hormone-producing Tumors in the GC Rat Model of Acromegaly
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Expression of molecular equivalent of hypothalamic–pituitary–adrenal axis in adult retinal pigment epithelium
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Glucose metabolism disorders in patients with non-functioning adrenal adenomas — single-centre experience
PublicationIntroduction: The presence of glucose metabolism disorders and their possible correlation with degree of cortisol secretion were evaluated in patients with non-functioning adrenal incidentalomas (NFAIs). Material and methods: The study group consisted of 131 patients with hormonally inactive adrenal incidentalomas....
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Regarding the “Review of surgical techniques and guide for decision making in the treatment of benign parotid tumors”
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Germ cell-like telomeric length homeostasis in nonseminomatous testicular germ cell tumors
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Microneedle‐Based Generation of Microbubbles in Cancer Tumors to Improve Ultrasound‐Assisted Drug Delivery
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The potential anti-tumor activity of neoteric solvents
PublicationCiecze jonowe stały się obiektem zainteresowania naukowców. Znajdują one coraz to szersze zastosowanie. Dlatego też ważne jest określenie ich właściwości Eko-toksycznych. Aktywność anty-nowotworowa i cytotoksyczna cieczy jonowych stała się zatem ważnym aspektem badań. Artykuł podsumowuje najnowsze wyniki badań nad cytotoksycznością tych rozpuszczalników
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Neural network agents trained by declarative programming tutors
PublicationThis paper presents an experimental study on the development of a neural network-based agent, trained using data generated using declarative programming. The focus of the study is the application of various agents to solve the classic logic task – The Wumpus World. The paper evaluates the effectiveness of neural-based agents across different map configurations, offering a comparative analysis to underline the strengths and limitations...
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Theoretical Study of Damage to DNA by 0.2−1.5 eV Electrons Attached to Cytosine
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<p>Nanomechanics and Histopathology as Diagnostic Tools to Characterize Freshly Removed Human Brain Tumors</p>
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Testing for NRAS Mutations in Serous Borderline Ovarian Tumors and Low-Grade Serous Ovarian Carcinomas
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Positive electrostatic therapy of metastatic tumors: selective induction of apoptosis in cancer cells by pure charges
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Classification of Thyroid Tumors Based on Mass Spectrometry Imaging of Tissue Microarrays; a Single-Pixel Approach
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Loss of DRO1/CCDC80 in the tumor microenvironment promotes carcinogenesis
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Image Segmentation of MRI image for Brain Tumor Detection
Publicationthis research work presents a new technique for brain tumor detection by the combination of Watershed algorithm with Fuzzy K-means and Fuzzy C-means (KIFCM) clustering. The MATLAB based proposed simulation model is used to improve the computational simplicity, noise sensitivities, and accuracy rate of segmentation, detection and extraction from MR...
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EFFECTS OF DOWNHILL AND UPHILL EXERCISES OF EQUIVALENT SUBMAXIMAL INTENSITIES ON SELECTED BLOOD CYTOKINE LEVELS AND BLOOD CREATINE KINASE ACTIVITY
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Selected adipocytokines in patients with an incidentally discovered pheochromocytoma
PublicationBACKGROUND: Adipose tissue secretes many adipokines and cytokines, which may be an additional risk factor of cardiovascular and metabolic diseases in patients with an incidentally discovered pheochromocytoma (PHEO). The aim of the study was to investigate levels of selected adipocytokines in these patients. METHODS: This prospective study included 12 patients with an incidentally discovered PHEO and 18 healthy participants. In...
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What are the true volumes of SEGA tumors? Reliability of planimetric and popular semi-automated image segmentation methods
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Effects of Interferon �-1a and Interferon �-1b Monotherapies on Selected Serum Cytokines and Nitrite Levels in Patients with Relapsing-Remitting Multiple Sclerosis: A 3-Year Longitudinal Study
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Insufficiency of the zona glomerulosa of the adrenal cortex and progressive kidney insufficiency following unilateral adrenalectomy – case report and discussion
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Deep convolutional neural network for predicting kidney tumour malignancy
PublicationPurpose: According to the statistics, up to 15-20% of removed solid kidney tumors turn out to be benign in postoperative histopathological examination, despite having been identified as malignant by a radiologist. The aim of the research was to limit the number of unnecessary nephrectomies of benign tumors. Methods or Background: We propose a machine-aided diagnostic system for kidney...