Search
displaying 1000 best results Help
Search results for: INHIBITORS OF ANGIOGENESIS
-
Structural features responsible for control of the eukaryotic GlcN-6-P synthase activity
PublicationGlucosamine-6-phosphate (GlcN-6-P) synthase is responsible for catalysis of the first and practically irreversible step in hexosamine metabolism. As UDP-GlcNAc, the final product of the hexosamine path, constitutes one of the essential substrates for assembly of bacterial and fungal cell walls, the enzyme is an interesting target for antimicrobial therapy.The structure of E. coli enzyme, known since 2001, forms a dimer of two identical...
-
MutS3: a MutS homologue of unknown biological function
PublicationThe homologues of MutS proteins are widespread among both Prokaryotes and Eukaryotes. MutS designated as MutS1 is a part of MMR (mismatch repair) system which is responsible for removal of mispaired bases and small insertion/deletion loops in DNA. Initially, the only MutS homologues known were those engaged in mismatch repair and these were later designated as MutS1. Subsequently, the MutS2 homologue was distinguished. MutS2 does...
-
Regulation of LPS assembly via controlled proteolysis and sensing of LPS stress in Escherichia coli
PublicationLipopolysaccharide (LPS) is a complex glycolipid, essential for the bacterial viability and along with phospholipids, it constitutes the major amphiphilic component of outer membrane (OM) in most of the Gram-negative bacteria, including Escherichia coli. LPS molecules confer an effective permeability barrier to the OM and play a crucial role in bacteria-environment and -host interactions. The synthesis and accumulation of this...
-
Structure modification of acridine antitumor agents results in changes of enzymatic activity and gene expression of CYP3A4 isoenzyme in HepG2 cells.
PublicationEkspresja izoenzymu CYP3A4, który zaangażowany jest w metabolizm ok. 60% leków stosowanych klinicznie, może być modulowana przez takie czynniki jak: polimorfizm, czynniki transkrypcyjne oraz obecność ksenobiotyków. Przykładem induktorów genów kodujących izoenzym CYP3A4 jest fenobarbital i rifampicyna, których obecność w organizmie przyspiesza metabolizm innych leków stosowanych jednocześnie, które są substratami dla CYP3A4. Dlatego...
-
Laboratorium Drgań i Zjawisk Falowych/Laboratory of vibrations and wave phenomena
e-Learning Courses -
Fundamentals of Automatics, W, Energetyka, sem.05, zimowy 22/23 (PG_00042102)
e-Learning CoursesThis course is on the Fundamentals of Automatics and prepared for students of BSc program in Power Engineering, specialization Energy Technologies, semester 5.
-
Physical and chemical basis of energy generation - GT 2021-2022 laboratory
e-Learning Courses -
Selected topics in electrical engineering – modelling of, electrical machines [2021/22]
e-Learning Courses -
Elective Project II: MOVABLE HOUSE – the home of a Modern Nomad
e-Learning CoursesAs part of the elective seminar, students working in groups of 3 people will prepare architectural and lighting concept for an international competition: "MOVABLE HOUSE – The Home of a Modern Nomad " organized by the Polish Lighting Industry Association), co-organized by Goczołowie Architekci OVO Grąbczewscy Architects and the SOMA Agency, the organizer of the International LIGHT Fair. More information here about the competition...
-
Reliability of Structures - 3rd semester, Civil Engineering - Winter Semester 2024/25
e-Learning CoursesReliability of Structures, 2nd grade studies, Civil Engineering
-
Stability & Dynamics of Ship and Offshore Structures II W2021/22
e-Learning CoursesLecture and Lab classes - Stability & Dynamics of Ship and Offshore Structures II W2021/22
-
Laboratorium drgań i zjawisk falowych / Laboratory of vibrations and wave phenomena
e-Learning CoursesSpecjalność: Fizyka stosowana (WFTiMS),I stopnia - inżynierskie, stacjonarne, 2020/2021 - zimowy (obecnie sem. 3)Specjalność: Inżynieria odnawialnych źródeł energii (WFTiMS),I stopnia - inżynierskie, stacjonarne, 2020/2021 - zimowy (obecnie sem. 3)
-
Gravity-related research (Engineering and Management of Space Systems) 21/22
e-Learning CoursesThe goal of the subject is to extend of the knowledge gained in the framework of general mechanics (statics, kinematics, dynamics). Students will be familiarized with the description of the kinematics and dynamics of motion in typical gravity-related research conditions (microgravity in parabolic flights, drop towers, sounding rockets) as well as gravity-related research platforms, its opportunities and limitations. Additionally,...
-
Stability & Dynamics of Ship and Offshore Structures I S2020/21
e-Learning CoursesLectures and exercises from the course "Stability & Dynamics of Ship and Offshore Structures I"
-
7. Elements of Asian history, culture, society and economy part 2
e-Learning Courses -
Fundamentals of Electrotechnics and Electronics II - project China [EE][2024/25]
e-Learning CoursesIntroduction and analysis of fundamental electronic components, circuits and applications.
-
Application of Mathematics in Technology, ET, sem 3, 23/24, (PG_00049767)
e-Learning CoursesApplication of Mathematics MOODLE ENV localdevtestprod
-
Methodology of teamwork, W, DAPE, sem.04, lato 22/23 (PG_00040179)
e-Learning CoursesMethodology of teamwork - lecture
-
Fundamentals of Machine Design II, PG_00050280, DaPE, sem. letni, 2023/24
e-Learning Courses -
Methodology of teamwork, S, DAPE, sem.04, lato 22/23 (PG_00040179)
e-Learning CoursesSeminar for Mthodology of teamwork subject
-
Natural fish oil improves the differentiation and maturation of oligodendrocyte precursor cells to oligodendrocytes in vitro after interaction with the blood–brain barrier
PublicationThe blood–brain barrier (BBB) tightly controls the microenvironment of the central nervous system (CNS) to allow neurons to function properly. Additionally, emerging studies point to the beneficial effect of natural oils affecting a wide variety of physiological and pathological processes in the human body. In this study, using an in vitro model of the BBB, we tested the influence of natural fish oil mixture (FOM) vs. borage oil...
-
Peptide Permeases in Candida albicans
PublicationAims: The aim of this work was to characterize oligopeptide uptake in Candida albicans mutants in which the genes encoding putative peptide permeases were selectively disrupted. Initial velocities of transport of model oligopeptides, (Ala)2, (Ala)3, (Ala)4, and sensitivity of mutants to antifungal oligopeptides containing N3-(4-methoxyfumaroyl)-L-2,3-diaminopropanoic acid (FMDP) were determined and compared to those of the wild-type...
-
Essential oils as potential anti-staphylococcal agents
PublicationAntibiotic therapy of staphylococcal mastitis is characterized by significantly lower cure rates compared to infections caused by other microorganisms. Thus, it is necessary to search for new, alternative, non-antibiotic agents that are effective in the eradication of these bacteria. The aim of our research was to investigate the antimicrobial, especially anti-staphylococcal potential of a large collection (n=36) of essential oils...
-
Composition and antimicrobial activity of fatty acids detected in the hygroscopic secretion collected from the secretory setae of larvae of the biting midge Forcipomyia nigra (Diptera: Ceratopogonidae)
PublicationThe hygroscopic secretion produced by the secretory setae of terrestrial larvae of the biting midge Forcipomyia nigra (Winnertz) was analysed using gas chromatography coupled with mass spectrometry (GC-MS). The viscous secretion is stored at the top of each seta and absorbs water from moist air. GC-MS analyses (four independent tests) showed that the secretion contained 12 free fatty acids, the most abundant of which were oleic...
-
One-pot synthesis of O-2-isocepham and N-2-isocepham derivatives bearing retroamide/tioretroamide or phosphono/thiophosphono function through the metal promoted cyclization – potential β-lactam antibiotics and β-lactamase inhibitors.
ProjectsProject realized in Department of Pharmaceutical Technology and Biochemistry
-
Methods of Experiment Design, W, E, sem.01, letni 22/23 (PG_00057505)
e-Learning Courses -
Application of Mathematics in Technology, ET, sem. 3, winter 2022/2023, (PG_00049767)
e-Learning CoursesApplication of Mathematics lectures and exercises
-
Methodology of teamwork - S, DAPE, sem.04, lato 21/22 (M:32009W0)
e-Learning Courses -
[Soft Skills] Decentralized energy systems. Social aspects of energy production and use
e-Learning Courses{mlang pl} Dyscyplina: soft skills Zajęcia obowiązkowe dla doktorantów II roku, Prowadzący: dr inż. Andrzej Augusiak, doc. PG Liczba godzin: 10 Forma zajęć: {mlang} {mlang en} Discipline: soft skills Obligatory course for 2nd-year PhD students Academic teacher: dr inż. Andrzej Augusiak, doc. PG Total hours of training: 10 teaching hours Course type: {mlang}
-
Fundamentals of new material technologies, P, DaPE, sem.06, letni 22/23
e-Learning Courses -
Methods of Experiment Design, W, E, sem.01, letni 21/22 (PG_00057505)
e-Learning Courses -
Planning of experiments and error analysis, W, MiBM, letni 21/22 (PG_00057374)
e-Learning Courses -
Advanced design of energy installations, P, MiBM, sem. 07, zimowy 22/23
e-Learning Courses -
Fundamentals of Automatics L, Energy Technologies, sem. 05, zimowy 22/23, PG_00042102
e-Learning CoursesFundamentals of Automatics 2022
-
Fundamentals of new material technologies, W, DaPE, sem.06, letni 23/24
e-Learning Courses -
[AEiE, ITiT] Scientific methods of computer data analysis and presentation - 2022/2023
e-Learning Courses{mlang pl} Dyscyplina: AEiE, ITiT Zajęcia obowiązkowe dla doktorantów II roku Prowadzący: Tomasz Berezowski Liczba godzin: 30 Forma zajęć: wykład/projekt/seminarium {mlang} {mlang en} Discipline: AEiE, ITiT Obligatory course for 2nd-year PhD students Academic teacher: Tomasz Berezowski Total hours of training: 30 teaching hours Course type: Lecture/project/seminar {mlang}
-
Research project: CAD. Integrated archictural design + Methodology of scientific work 2022/2023
e-Learning CoursesKurs e-learningowy stanowi uzupełnienie zajęć stacjonarnych Projekt Naukowy (Techniki Komputerowe i Metodyka Pracy Naukowej) dla studentów II stopnia (2 semestr) Zajęcia dotyczą zastosowania środowiska GIS i oprogramowania BIM oraz odpowiednich metod naukowych w procesie projektowania i przekształcania obszarów waterfrontów.
-
Methodology of teamwork - L, DAPE, sem.04, lato 21/22 (M:32009W0)
e-Learning Courses -
Methods of Experiment Design, S, E, sem.01, letni 21/22 (PG_00057505)
e-Learning Courses -
Methods of Experiment Design, S, E, sem.01, letni 22/23 (PG_00057505)
e-Learning Courses -
Planning of experiments and error analysis, C, MiBM, letni 21/22 (PG_00057374)
e-Learning Courses -
Fundamentals of new material technologies,P, DPE, sem.6 letni 23/24
e-Learning Courses -
6. Elements of Asian history, culture, society and economy zima 2020/2021
e-Learning Courses -
Advanced design of energy installations, W MiBM, sem. 07, zimowy 22/23
e-Learning Courses -
[EiF] [ZiJ] Writing scientific papers for Management and Economics Fields of Science
e-Learning Courses{mlang pl} Dyscyplina: soft skills Zajęcia obowiązkowe dla doktorantów I i II roku z dyscyplin EiF oraz ZiJ, Prowadzący: dr hab inż. Aleksandra Parteka, prof. PG Liczba godzin: 5 Forma zajęć: {mlang} {mlang en} Discipline: soft skills Obligatory course for 1st and 2nd-year PhD students of EiF and ZiJ disciplines Academic teacher: dr hab. inż. Aleksandra Parteka, prof. PG Total hours of training: 5 teaching hours Course...
-
[AEEiTK, ITiT] Scientific methods of computer data analysis and presentation - 2023/2024
e-Learning Courses{mlang pl} Dyscyplina: AEiE, ITiT Zajęcia obowiązkowe dla doktorantów II roku Prowadzący: Tomasz Berezowski Liczba godzin: 30 Forma zajęć: wykład/projekt/seminarium {mlang} {mlang en} Discipline: AEiE, ITiT Obligatory course for 2nd-year PhD students Academic teacher: Tomasz Berezowski Total hours of training: 30 teaching hours Course type: Lecture/project/seminar {mlang}
-
Building Mechanics I ERASMUS (PG_00049121) 2019/2020 - 2nd sem. of bachelor studies
e-Learning Courses -
Methods of Experiment Design, W/S, Energetyka, sem. 1, letni, 2023/24
e-Learning Courses -
6. Elements of Asian history, culture, society and economy zima 2023/2024
e-Learning Courses -
[AEEiTK, ITiT] Scientific methods of computer data analysis and presentation 2024/2025
e-Learning Courses{mlang pl} Dyscyplina: AEiE, ITiT Zajęcia obowiązkowe dla doktorantów II roku Prowadzący: Tomasz Berezowski Liczba godzin: 30 Forma zajęć: wykład/projekt/seminarium {mlang} {mlang en} Discipline: AEiE, ITiT Obligatory course for 2nd-year PhD students Academic teacher: Tomasz Berezowski Total hours of training: 30 teaching hours Course type: Lecture/project/seminar {mlang}