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Catalytic Mechanism of Non-Target DNA Cleavage in CRISPR-Cas9 Revealed by Ab Initio Molecular Dynamics
PublicationCRISPR-Cas9 is a cutting-edge genome editing technology, which uses the endonuclease Cas9 to introduce mutations at desired sites of the genome. This revolutionary tool is promising to treat a myriad of human genetic diseases. Nevertheless, the molecular basis of DNA cleavage, which is a fundamental step for genome editing, has not been established. Here, quantum–classical molecular dynamics (MD) and free energy methods are used...
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Łukasz Markiewicz mgr inż.
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Selected aspects of heat recovery simulation in houseboat installations
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Sésame, ouvre-toi: internationalisme phraséologique à contenu universel
PublicationPhraseological units, characterised by their opaque meaning, are the subject of multiple theoretical works. The following article adds to this discussion by providing another interesting example. It analyses the case of the Arabic phraseological unit ‘open sesame’ from the “Ali Baba and the Forty Thievesˮ folk tale, permeating into French, Italian, Polish, Turkish and Japanese – languages distant both linguistically and culturally....
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Plasma cell myeloma - Male, 73 - Tissue image [11290630017282921]
Open Research DataThis is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Waldenstrom macroglobulinemia - Female, 50 - Tissue image [11290630017299501]
Open Research DataThis is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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The impact of mega sports events on the stock markets
PublicationWpływ wielkoformatowych imprez sportowych na gospodarkę może być rozpatrywany na różnych płaszczyznach. Najczęściej przywołuje się zmiany w zakresie PKB kraju lub regionu goszczącego, zmiany na rynku pracy, rozbudowę bądź modernizację infrastruktury oraz tendencje w zakresie przepływu turystycznego. Kanały oddziaływania tak dużych wydarzeń są jednak dużo szersze i obejmują ponadto: życie publiczne, polityczne i kulturalne, informację,...
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[EiF] [ZiJ] Writing scientific papers for Management and Economics Fields of Science
e-Learning Courses{mlang pl} Dyscyplina: soft skills Zajęcia obowiązkowe dla doktorantów I i II roku z dyscyplin EiF oraz ZiJ, Prowadzący: dr hab inż. Aleksandra Parteka, prof. PG Liczba godzin: 5 Forma zajęć: {mlang} {mlang en} Discipline: soft skills Obligatory course for 1st and 2nd-year PhD students of EiF and ZiJ disciplines Academic teacher: dr hab. inż. Aleksandra Parteka, prof. PG Total hours of training: 5 teaching hours Course...
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DATA MINING (Field of study: Economic analytics 1st semester) -2022
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Kryptologia [Matematyka 2023/24]
e-Learning CoursesKryptologia, st. II, sem. 3, Matematyka
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Kryptografia [2022/23]
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Analiza Matematyczna 1 MAT 1001/1 (2021/22)
e-Learning CoursesAnaliza Matematyczna 1 semestr 1 kod MAT 1001/1 rok 21/22
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Bazy Danych sem. 4 (2022/23)
e-Learning CoursesKurs wspomagający prowadzenie zajęć z Baz Danych. 2022/23
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Kryptologia [2022/23]
e-Learning CoursesKryptologia, st. II, sem. 3, Matematyka
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Algorytmy i Struktury Danych [2022/23]
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Wstęp do teorii miary - 22/23 ćw.
e-Learning CoursesWstęp do teorii miary, rok akad. 2022/23, ćwiczenia Matematyka sem. 3
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Wstęp do teorii miary - 23/24 ćw.
e-Learning CoursesWstęp do teorii miary, rok akad. 2023/24, ćwiczenia Matematyka sem. 3
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Algebra liniowa 2023/2024
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Wstęp do teorii miary
e-Learning CoursesWstęp do teorii miary 3 semestr Matematyki Stosowanej
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Kryptografia [2023/24]
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Neurohypophyseal Receptors-Ligands: Where We Are After the Landmark Rhodopsin Structure Determination
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Theoretical Study of Polymerization Mechanism of p-Xylylene Based Polymers
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Theoretical study of polymerization mechanism of p-xylylene based polymers
PublicationObliczenia kwantowe mechanizmu polimeryzacji parylenów, opartych o cząsteczki p-ksylilenów. Praca zawiera wyniki szczegółowych obliczeń wszystkich etapów polimeryzacji, wnioski dotyczące znalezionych stanów kwantowych i energetyki poszczególnych etapów procesu.
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Yerba Mate—A Long but Current History
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Establishing the allosteric mechanism in CRISPR‐Cas9
PublicationAllostery is a fundamental property of proteins, which regulates biochemical information transfer between spatially distant sites. Here, we report on the critical role of molecular dynamics (MD) simulations in discovering the mechanism of allosteric communication within CRISPR‐Cas9, a leading genome editing machinery with enormous promises for medicine and biotechnology. MD revealed how allostery intervenes during at least three...
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Joanna Gizela Rokicka dr inż.
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Reduction of spectral interferences in atmospheric pressure glow discharge optical emission spectrometry
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Bioaccessibility of Ca, Cu, Fe, Mg, Mn and Zn from commercial bee honeys
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On the coupling of hydride generation with atmospheric pressure glow discharge in contact with the flowing liquid cathode for the determination of arsenic, antimony and selenium with optical emission spectrometry
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Flowing Liquid Anode Atmospheric Pressure Glow Discharge as an Excitation Source for Optical Emission Spectrometry with the Improved Detectability of Ag, Cd, Hg, Pb, Tl, and Zn
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Direct elemental analysis of honeys by atmospheric pressure glow discharge generated in contact with a flowing liquid cathode
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Development and optimization of simplified method of fast sequential HR-CS-FAAS analysis of apple juices on the content of Ca, Fe, K, Mg, Mn and Na with the aid of response surface methodology
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HR-CS FAAS based method for direct determination of total concentrations of Ca, Fe, Mg and Mn in functional apple beverages and evaluation of contributions of the bioaccessible fraction of these elements by in vitro gastrointestinal digestion and chemical fractionation
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S’attaquer à la suprématie du masculin sur le féminin : le français inclusif dans les publications des universités françaises dans les réseaux sociaux
PublicationThis paper aims to examine the use of inclusive French in the Internet publications of Paris universities on their social media. Three higher education institutions were selected: Paris Dauphine-PSL University, Gustave Eiffel University, and Sorbonne Paris North University. The publications were obtained from Facebook, Instagram, and LinkedIn. Firstly, the groups of people to whom the use of inclusive French referred...
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Emisja kwitów depozytowych jako źródło finansowania przedsiębiorstw z krajów BRIC
PublicationDostęp do źródeł kapitału jest jednym z najważniejszych czynników rozwoju przedsiębiorstw, niezależnie od poziomu rozwoju krajów, w których działają. Jednym ze sposobów finansowania działalności gospodarczej jest emisja akcji na rynku pierwotnym lub wtórnym Odgrywające coraz ważniejszą rolę w światowym systemie gospodarczym kraje BRIC (Brazylia, Rosja, Indie, Chiny) cechuje różnorodność struktur finansowania przedsiębiorstw, z...
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Damian Gierad
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Synthesis Attempt and Structural Studies of Novel A2CeWO6 Double Perovskites (A2+ = Ba, Ca) in and outside of Ambient Conditions
PublicationSynthesis Attempt and Structural Studies of Novel A 2 CeWO 6 Double Perovskites (A 2+ = Ba, Ca) in and outside of Ambient Conditions Damian Wlodarczyk,* Mikolaj Amilusik, Katarzyna M. Kosyl, Maciej Chrunik, Krystyna Lawniczak-Jablonska, Michal Strankowski, Marcin Zajac, Volodymyr Tsiumra, Aneta Grochot, Anna Reszka, Andrzej Suchocki, Tomasz Giela, Przemyslaw Iwanowski, Michal Bockowski, and Hanka Przybylinska Cite This: ACS Omega...
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Myelofibrosis as a result of myeloproliferative disease - Male, 67 - Tissue image [11290630017286401]
Open Research DataThis is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Green method of conversion of geraniol to value-added products in the presence of selected minerals
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Conversion of Geraniol into Useful Value-Added Products in the Presence of Catalysts of Natural Origin: Diatomite and Alum
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Minute and diverse in fossil sticky stuff: Tanytarsini (Diptera: Chironomidae) from early Eocene Indian Cambay amber
PublicationWe here present a pioneering systematic review of fossil dipterans of the tribe Tanytarsini (family Chironomidae) discovered in Indian amber from Cambay. The specimens examined belong to five species: Gujaratomyia miripes, Stempellina stebneri sp. nov., Stempellinella pollex sp. nov., Tanytarsus forfex sp. nov. and Tanytarsus ramus sp. nov., which are described. All species belong to the oldest known Tanytarsini and come from the...
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Experimental investigation into surface texture effect on journal bearings performance
PublicationThe aim of this study was to analyse the performance of journal bearings with specially created dimples on the sliding surface and operating under various conditions. The texture was created on the bearing surface that co-acted with the smooth journal; moreover, the variation of the textured surface of the journal mating with the smooth bearing was tested, and the results were compared to those obtained with the standard smooth...
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Direct Current Atmospheric Pressure Microdischarge Generated between a Miniature Flow Helium Microjet and a Flowing Liquid Cathode
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The improvement of the analytical performance of direct current atmospheric pressure glow discharge generated in contact with the small-sized liquid cathode after the addition of non-ionic surfactants to electrolyte solutions
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Assessment of the Impact of Loss-of-Retention Fees on Green Infrastructure Investments
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Dynamics analysis of footbridge mode shapes the s8 expressway on the basis of the results of in situ tests
PublicationNon-destructive diagnostics for structure may use dynamic measurements realized during vibrations of a facility induced by dynamic environmental impact, enforced by the use of inductors or impulse impact. Dynamic tests and the analysis were undertaken for a footbridge situated over the expressway S8. The studies in situ allowed for dynamic characteristics to be determined: frequency, shape modes and damping for respective frequency...
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Hydraulika inżynierska 2021/2022
e-Learning CoursesKurs do przedmiotu HYDRAULIKA Kierunek: Budownictwo (WILiŚ), I stopnia - inżynierskie, niestacjonarne dr hab. inż. Michał Szydłowski, prof. uczelni rok akademicki 2021/2022 (semestr letni)
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Nawigacja lotnicza i meteorologia 2022/2023
e-Learning Courseskursu wspomagający do przedmiotu: Nawigacja lotnicza i meteorologia kierunek: Geodezja i Kartografia specjalność: Fotogrametria Niskiego Pułapu semestr: V
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Meteorologia i klimatologia - IŚ, inż., stacjonarne, sem.II 2021/2022
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Nawigacja lotnicza i meteorologia 2023/2024
e-Learning Courseskursu wspomagający do przedmiotu: Nawigacja lotnicza i meteorologia kierunek: Geodezja i Kartografia specjalność: Fotogrametria Niskiego Pułapu semestr: V