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Search results for: IN VITRO METABOLIZM
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Correction: Corrigendum: Modulation of expression of genes involved in glycosaminoglycan metabolism and lysosome biogenesis by flavonoids
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The role of cytochrome P450 reductase (CPR) in metabolism of potent nitroacridine antitumor, C-1748
PublicationCelem pracy było poznanie molekularnego mechanizmu działania pochodnych 9-amino-1-nitroakrydyny. Zbadano przemiany enzymatyczne tych związków w różnych układach enzymatycznych: I. Szczurza frakcja mikrosomalna z reduktazą cytochromu P450. II. Rekombinantowe izoenzymy cytochromu P450 z wysokim i niskim poziomem reduktazy cytochromu P450. III. Frakcje mikrosomalne dzikiego typu oraz pozbawione genu kodującego reduktazę cytochromu...
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Skin microbiota metabolism of natural products from comfrey root (Symphytum officinale L.)
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DRUG METABOLISM AND DISPOSITION
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DRUG METABOLISM REVIEWS
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Carbon assimilation profiles of mucoralean fungi show their metabolic versatility
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Significance of selected inflammatory factors in metabolic disorders in association with psoriasis
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Electronic Cigarette Use and Metabolic Syndrome Development: A Critical Review
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Flavonoid biosynthetic pathways in plants: Versatile targets for metabolic engineering
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The usefulness of fluorescence in detecting ischemia during bariatric and metabolic surgery
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A numerical scale to assess the outcomes of metabolic/bariatric surgery (NOMS)
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Metabolic profiling of pteridines for determination of potential biomarkers in cancer diseases
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The metabolic syndrome in hypertension: European society of hypertension position statement
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Bisphenol A analogues and metabolic syndrome in women with polycystic ovary syndrome
PublicationBisphenols (BPs) have become a chemical group of special interest due to their ability to interfere with the endocrine system and their ubiquitous presence in the environment. As some of them possess mild estrogenic and anti-androgenic effects, they might be associated with the diagnosis of polycystic ovary syndrome (PCOS). Acting on multiple tissues, BPs exposure may lead to metabolic derangements characteristic for metabolic...
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IFI16 Impacts Metabolic Reprogramming during Human Cytomegalovirus Infection
PublicationCellular lipid metabolism plays a pivotal role in human cytomegalovirus (HCMV) infection, as increased lipogenesis in HCMV-infected cells favors the envelopment of newly synthesized viral particles. As all cells are equipped with restriction factors (RFs) able to exert a protective effect against invading pathogens, we asked whether a similar defense mechanism would also be in place to preserve the metabolic compartment from HCMV...
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Preparation and in vitro characterisation of bioactive mesoporous silica microparticles for drug delivery applications
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Synthesis and in vitro characterization of freeze-dried doxorubicin-loaded silica/PEG composite
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Anticancer properties of low molecular weight oat beta-glucan – An in vitro study
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Edible Flowers Extracts as a Source of Bioactive Compounds with Antioxidant Properties—In Vitro Studies
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Parallel in vitro and in silico investigations into anti-inflammatory effects of non-prenylated stilbenoids
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In vivo and in vitro study of a novel nanohydroxyapatite sonocoated scaffolds for enhanced bone regeneration
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The effect of electromagnetic field on reactive oxygen species production in human neutrophilsin vitro
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In vitro enzyme inhibitory properties, antioxidant activities, and phytochemical profile of Potentilla thuringiaca
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In vitro anticariogenic effects of aerial parts of Drymocallis rupestris and its phytochemical profile
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In vitro anticariogenic effects of aerial parts of Potentilla recta and its phytochemical profile
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Polyphenol-Enriched Composite Bone Regeneration Materials: A Systematic Review of In Vitro Studies
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Cinnamon powder: an in vitro and in vivo evaluation of antifungal and plant growth promoting activity
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Transcriptional activity of epigenetic remodeling genes declines in keratinocytes after in vitro expansion
PublicationPURPOSE: In vitro expansion is an invaluable method to obtain keratinocytes in amounts necessary for effective transplantation therapies. In vitro cell culturing provokes questions concerning potential epigenetic alterations occurring in expanded cells in the context of usefulness for transplantation and safety. The purpose of this study was to investigate as to whether keratinocyte expansion is associated with changes in the activity...
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Specificity of Infant Digestive Conditions: Some Clues for Developing Relevant In Vitro Models
PublicationDigestion of nutrients is an essential function of the newborn infant gut to allow growth and development and understanding infant digestive function is essential to optimize nutrition and oral drug delivery. Ethical considerations prohibit invasive in vivo trials and as a consequence in vitro assays are often conducted. However, the choice of in vitro model parameters are not supported by an exhaustive analysis of the literature...
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Butyrylcholinesterase signal sequence self-aggregates and enhances amyloid fibril formation in vitro
PublicationAlzheimer’s disease (AD) pathogenesis has been attributed to extracellular aggregates of amyloid β (Aβ) plaques and neurofibrillary tangles in the human brain. It has been reported that butyrylcholinesterase (BChE) also accumulates in the brain Aβ plaques in AD. We have previously found that the BChE substitution in 5′UTR caused an in-frame N-terminal extension of 41 amino acids of the BChE signal peptide. The resultant variant...
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PTD4 Peptide Increases Neural Viability in an In Vitro Model of Acute Ischemic Stroke
PublicationIschemic stroke is a disturbance in cerebral blood flow caused by brain tissue ischemia and hypoxia. We optimized a multifactorial in vitro model of acute ischemic stroke using rat primary neural cultures. This model was exploited to investigate the pro-viable activity of cell-penetrating peptides: arginine-rich Tat(49–57)-NH2 (R49KKRRQRRR57-amide) and its less basic analogue, PTD4 (Y47ARAAARQARA57-amide). Our model included glucose...
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DIABETES-METABOLISM RESEARCH AND REVIEWS
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International Journal of Endocrinology and Metabolism
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Journal of Drug Metabolism & Toxicology
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Expert Review of Endocrinology & Metabolism
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Mediterranean Journal of Nutrition and Metabolism
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Indian Journal of Endocrinology and Metabolism
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Therapeutic Advances in Endocrinology and Metabolism
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Iranian Journal of Endocrinology and Metabolism
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Annals of Pediatric Endocrinology and Metabolism
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Journal of Nutrition and Intermediary Metabolism
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Turkish Journal of Endocrinology and Metabolism
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Drug Metabolism and Personalized Therapy
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JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
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Chinese Journal of Endocrinology and Metabolism
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JOURNAL OF BONE AND MINERAL METABOLISM
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JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
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International Journal of Diabetes and Metabolism
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Completing Autophagy: Formation and Degradation of the Autophagic Body and Metabolite Salvage in Plants
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Metabolism of 1α-hydroxyvitamin D3 by cytochrome P450scc to biologically active 1α,20-dihydroxyvitamin D3
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