Rok 2016

• Antitumor DNA-Damaging C-1748 is a New Inhibitor of Autophagy that Triggers Apoptosis in Human Pancreatic Cancer Cell Lines

  Publikacja

  • B. Borowa-Mazgaj
  • A. Skwarska
  • E. Augustin
  • A. Radominska-Pandya
  • Z. Mazerska

  - FASEB JOURNAL - Rok 2016

  Despite the enormous progress that has been made over the past decades in diagnosis, treatment and prevention of many types of tumors, survival rates in pancreatic cancer still remain poor. Pancreatic cancer is one of the most malignant and chemoresistant tumors and the profound mechanism supporting these phenomena is the constitutively activated prosurvival autophagy. The antitumor 1-nitroacridine derivative C-1748 belongs to...

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