dr hab. Daniel Gackowski
Zatrudnienie
- 2019 - present Professor w Department of Clinical Biochemistry
- 2003 - 2019 Associate professor w Department of Clinical Biochemistry, Collegium Medicum in Bydgoszcz
- 1998 - 1999 technician w Department of Clinical Biochemistry
Obszary badawcze
- Brak danych
Publikacje
Filtry
wszystkich: 70
Katalog Publikacji
Rok 2021
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Quantification of DNA Modifications Using Two-Dimensional Ultraperformance Liquid Chromatography Tandem Mass Spectrometry (2D-UPLC-MS/MS)
Publikacja -
Preparation of Internal Standards for 2D-UPLC-MS/MS Quantification of Noncanonical DNA Bases
Publikacja -
Mass Spectrometry-Based Analysis of DNA Modifications: Potential Applications in Basic Research and Clinic
Publikacja -
Analysis of 5-Hydroxymethyluracil Levels Using Flow Cytometry
Publikacja
Rok 2020
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Targeted DNA oxidation by LSD1–SMAD2/3 primes TGF-β1/ EMT genes for activation or repression
Publikacja -
N6-methyladenosine regulates the stability of RNA:DNA hybrids in human cells
Publikacja -
Context dependent effects of ascorbic acid treatment in TET2 mutant myeloid neoplasia
Publikacja -
5-formylcytosine and 5-hydroxymethyluracil as surrogate markers of TET2 and SF3B1 mutations in myelodysplastic syndrome, respectively
Publikacja
Rok 2019
Rok 2018
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Systemowa równowaga antyoksyacyjna u pacjentów bez klinicznej manifestacji miażdżycy
Publikacja -
Oxidation Products of 5-Methylcytosine are Decreased in Senescent Cells and Tissues of Progeroid Mice
Publikacja -
Modulation of TET2 Activity By Ascorbic Acid and Factors Affecting Lysine Acetylation
Publikacja -
In vivo evidence of ascorbate involvement in the generation of epigenetic DNA modifications in leukocytes from patients with colorectal carcinoma, benign adenoma and inflammatory bowel disease
Publikacja -
ERCC1-deficient cells and mice are hypersensitive to lipid peroxidation
Publikacja -
Endogenously generated DNA nucleobase modifications source, and significance as possible biomarkers of malignant transformation risk, and role in anticancer therapy
Publikacja -
Correction: Profiles of a broad spectrum of epigenetic DNA modifications in normal and malignant human cell lines: Proliferation rate is not the major factor responsible for the 5-hydroxymethyl-2′-deoxycytidine level in cultured cancerous cell lines
Publikacja -
Characteristic profiles of DNA epigenetic modifications in colon cancer and its predisposing conditions—benign adenomas and inflammatory bowel disease
Publikacja
Rok 2017
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Systemic oxidoreductive balance and vascular function in individuals without clinical manifestation of atherosclerosis
Publikacja -
Profiles of a broad spectrum of epigenetic DNA modifications in normal and malignant human cell lines: Proliferation rate is not the major factor responsible for the 5-hydroxymethyl-2′-deoxycytidine level in cultured cancerous cell lines
Publikacja
Rok 2016
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Vitamin C enhances substantially formation of 5-hydroxymethyluracil in cellular DNA
Publikacja -
Urinary Measurement of Epigenetic DNA Modifications: A Non-Invasive Assessment of the Whole-Body Epigenetic Status in Healthy Subjects and Colorectal Cancer Patients
Publikacja -
Nucleotide excision repair of oxidised genomic DNA is not a source of urinary 8-oxo-7,8-dihydro-2′-deoxyguanosine
Publikacja -
Enigmatic 5-hydroxymethyluracil: Oxidatively modified base, epigenetic mark or both?
Publikacja -
Accurate, Direct, and High-Throughput Analyses of a Broad Spectrum of Endogenously Generated DNA Base Modifications with Isotope-Dilution Two-Dimensional Ultraperformance Liquid Chromatography with Tandem Mass Spectrometry: Possible Clinical Implication
Publikacja
Rok 2015
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Urinary 5-hydroxymethyluracil and 8-oxo-7,8-dihydroguanine as potential biomarkers in patients with colorectal cancer
Publikacja -
Tissue-Specific Differences in DNA Modifications (5-Hydroxymethylcytosine, 5-Formylcytosine, 5-Carboxylcytosine and 5-Hydroxymethyluracil) and Their Interrelationships
Publikacja
Rok 2014
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Viral infection-oxidative stress/DNA damage-aberrant DNA methylation: separate or interrelated events responsible for genetic instability and childhood ALL development?
Publikacja -
Epigenetic modifications and NF-κB pathway activity in Cu,Zn-SOD-deficient mice
Publikacja -
Comparison of the Absolute Level of Epigenetic Marks 5-Methylcytosine, 5-Hydroxymethylcytosine, and 5-Hydroxymethyluracil Between Human Leukocytes and Sperm1
Publikacja -
Are 8-oxoguanine (8-oxoGua) and 5-hydroxymethyluracil (5-hmUra) oxidatively damaged DNA bases or transcription (epigenetic) marks?
Publikacja -
8-Oxo-7,8-dihydroguanine and uric acid as efficient predictors of survival in colon cancer patients
Publikacja
Rok 2013
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Human and Methodological Sources of Variability in the Measurement of Urinary 8-Oxo-7,8-dihydro-2′-deoxyguanosine
Publikacja -
Does morphology of carotid plaque depend on patient's oxidative stress?
Publikacja -
Comparison of Oxidative Stress/DNA Damage in Semen and Blood of Fertile and Infertile Men
Publikacja
Rok 2012
Rok 2011
Rok 2010
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Toward consensus in the analysis of urinary 8‐oxo‐7,8‐dihydro‐2′‐deoxyguanosine as a noninvasive biomarker of oxidative stress
Publikacja -
Oxidatively Damaged DNA/Oxidative Stress in Children with Celiac Disease
Publikacja -
Oxidative stress and 8-oxoguanine repair are enhanced in colon adenoma and carcinoma patients
Publikacja -
Aberrant repair of etheno–DNA adducts in leukocytes and colon tissue of colon cancer patients
Publikacja
Rok 2009
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Selenium Supplementation Reduced Oxidative DNA Damage in Adnexectomized BRCA1 Mutations Carriers
Publikacja -
Interlaboratory comparison of methodologies for the measurement of urinary 8-oxo-7,8-dihydro-2′-deoxyguanosine
Publikacja -
Elevated level of 8‐oxo‐7,8‐dihydro‐2′‐deoxyguanosine in leukocytes of BRCA1 mutation carriers compared to healthy controls
Publikacja
Rok 2008
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The relationship between 8-oxo-7,8-dihydro-2′-deoxyguanosine level and extent of cytosine methylation in leukocytes DNA of healthy subjects and in patients with colon adenomas and carcinomas
Publikacja -
Small field radiotherapy of head and neck cancer patients is responsible for oxidatively damaged DNA/oxidative stress on the level of a whole organism
Publikacja -
Oxidative stress and oxidative DNA damage is characteristic for mixed Alzheimer disease/vascular dementia
Publikacja -
Dynamics of Oxidative Damage at Early Stages of Estrogen-dependant Carcinogenesis
Publikacja
Rok 2007
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Urinary excretion rates of 8-oxoGua and 8-oxodG and antioxidant vitamins level as a measure of oxidative status in healthy, full-term newborns
Publikacja -
Higher Leukocyte 8-Oxo-7,8-Dihydro-2'-Deoxyguanosine and Lower Plasma Ascorbate in Aging Humans?
Publikacja -
Effects of basal level of antioxidants on oxidative DNA damage in humans
Publikacja
Rok 2006
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Urinary Measurement of 8-OxodG, 8-OxoGua, and 5HMUra: A Noninvasive Assessment of Oxidative Damage to DNA
Publikacja -
Severe oxidatively damaged DNA after cisplatin treatment of cancer patients
Publikacja -
Helicobacter pylori infection is associated with oxidatively damaged DNA in human leukocytes and decreased level of urinary 8-oxo-7,8-dihydroguanine
Publikacja -
Evidence for attenuated cellular 8-oxo-7,8-dihydro-2′-deoxyguanosine removal in cancer patients
Publikacja
Rok 2005
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Substantial decrease of urinary 8-oxo-7,8-dihydroguanine, a product of the base excision repair pathway, in DNA glycosylase defective mice
Publikacja -
Oxidative DNA damage and antioxidant vitamin level: Comparison among lung cancer patients, healthy smokers and nonsmokers
Publikacja -
Establishing the background level of base oxidation in human lymphocyte DNA: results of an interlaboratory validation study
Publikacja -
DNA repair is responsible for the presence of oxidatively damaged DNA lesions in urine
Publikacja -
Contribution of hMTH1 to the Maintenance of 8-Oxoguanine Levels in Lung DNA of Non-Small-Cell Lung Cancer Patients
Publikacja
Rok 2004
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Diet is Not Responsible for the Presence of Several Oxidatively Damaged DNA Lesions in Mouse Urine
Publikacja
Rok 2003
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Oxidative DNA damage in cancer patients: a cause or a consequence of the disease development?
Publikacja -
High Concentrations of Excised Oxidative DNA Lesions in Human Cerebrospinal Fluid
Publikacja
Rok 2002
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The level of 8-oxo-7,8-dihydro-2′-deoxyguanosine is positively correlated with the size of the labile iron pool in human lymphocytes
Publikacja -
Supplementation with antioxidant vitamins prevents oxidative modification of DNA in lymphocytes of HIV-infected patients
Publikacja -
Persistent oxidative stress in colorectal carcinoma patients
Publikacja -
Oxidative stress in humans: validation of biomarkers of DNA damage
Publikacja -
Oxidative DNA damage: assessment of the role in carcinogenesis, atherosclerosis, and acquired immunodeficiency syndrome1 1This article is part of a series of reviews on “Oxidative DNA Damage and Repair.” The full list of papers may be found on the homepage of the journal.
Publikacja
Rok 2001
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Further evidence that oxidative stress may be a risk factor responsible for the development of atherosclerosis
Publikacja -
8-Oxo-7,8-dihydroguanine and 8-oxo-7,8-dihydro-2′-deoxyguanosine levels in human urine do not depend on diet
Publikacja
Rok 2000
wyświetlono 425 razy