A dysfunction of cells lining the inner walls of blood vessels, i.e. the endothelium, is the primary cause of many lifestyle
related diseases. According to the WHO, those diseases accounted for 60% of all deaths worldwide in 2005. Tailor-made
diagnostic tools for early and reliable identification of endothelial dysfunction are urgently needed both in fundamental
research and clinical routine, respectively.
The Marie Skłodowska-Curie action LOGIC LAB objects to develop and characterize innovative molecular logic gates that
can be applied as advanced diagnostic tools for parallel analyte sensing in live mammalian cells. Thereby, providing a
unique method to discover endothelial dysfunction and the onset of diseases much easier and earlier than so far.
LOGIC LAB creates a multi-faceted and multi-sectoral research environment for the next generation of scientists in order to
establish a novel type of molecular logic sensors that reliably operate in biological media – a crucial requirement for their
application i.e. as rapid and easy-to-handle tools for intracellular diagnostics.
With excellent cross-disciplinary scientific and complementary training provided in the network, we aim to educate highlyskilled
young scientists in the fields of chemistry, physics and biology, who will significantly strengthen the international research community in the domain of molecular logic sensing. Thus, in the long term, LOGIC LAB aims to finally bridge the
gap between lab bench and biological or medical practice. It is this gap, that so far prevents a wide-ranging use of existing
molecular logic gates e.g. for the diagnosis of lifestyle-associated diseases.
Informacje szczegółowe
- Akronim projektu:
- LOGIC LAB
- Program finansujący:
- HORYZONT 2020
- Instytucja:
- Komisja Europejska
- Porozumienie:
- z dnia 2018-08-23
- Okres realizacji:
- 2018-11-01 - 2023-10-31
- Kierownik zespołu badawczego:
- dr hab. Julien Guthmuller
- Członkowie zespołu:
-
- kierownik dr hab. Julien Guthmuller
- Realizowany w:
- Katedra Fizyki Teoretycznej i Informatyki Kwantowej
- Instytucje zewnętrzne
biorące udział w projekcie: -
- SLOVAK ACADEMY OF SCIENCES (Słowacja)
- UNIVERSITEIT LEIDEN (Holandia)
- DUBLIN CITY UNIVERSITY (Irlandia)
- FRIEDRICH-SCHILLER-UNIVERSITAT JENA (Niemcy)
- UNIWERSYTET JAGIELLONSKI (Polska)
- LEIBNIZ-INSTITUT FUER PHOTONISCHE TECHNOLOGIEN E.V. (Niemcy)
- SciClus GmbH & Co. KG (Niemcy)
- MIMETAS BV (Holandia)
- Wartość projektu:
- 3 538 684.00 EUR
- Typ zgłoszenia:
- Międzynarodowy Program Badawczy
- Pochodzenie:
- Projekt zagraniczny/międzynarodowy
- Weryfikacja:
- Politechnika Gdańska
wyświetlono 128 razy