Anticarcinogenic and antioxidant activities of leaves and flowers hydroalcoholic extracts of Nerium oleander L.: PCA analysis and phytochemical content by FTIR spectroscopy - Publikacja - MOST Wiedzy

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Anticarcinogenic and antioxidant activities of leaves and flowers hydroalcoholic extracts of Nerium oleander L.: PCA analysis and phytochemical content by FTIR spectroscopy

Abstrakt

Aims: The aim of this work is the evaluation the anticarcinogenic effect on HT29 cancer cells lines and antioxidant effect of three extracts from different morphological parts (leaves (LE), pink flowers (PFE) and white flowers (WFE)) of Nerium oleander lin. Methods: This research provides the anticarcinogenic activity of extracts from N. oleander white flowers. Principal Component Analysis (PCA) was applied to estimate the relationship between antioxidant and anticarcinogenic activities, and to further understand the similarities and differences between the extracts. Results: All of the extracts exhibited different antioxidant (ABTS, DPPH and FC) and anticarcinogenic activities. FTIR analysis designed the existence of various functional groups in extracts confirming the presence of alcohol, alkanes, amino, aromatic compound and primary alcohol. The PCA results show that the WFE extract exhibits a greater antioxidant activity with a potent potential for inhibiting the cell growth of colorectal cancer HT29 than the two other extracts (LE and PFE). Conclusions: Nerium oleander may therefore be an excellent source of natural antioxidant and anticancer agents, as well as a possible pharmaceutical supplement.

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Accepted albo Published Version
DOI:
Cyfrowy identyfikator dokumentu elektronicznego (otwiera się w nowej karcie) 10.51745/najfnr.7.15.1-8
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Creative Commons: CC-BY otwiera się w nowej karcie

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Informacje szczegółowe

Kategoria:
Publikacja w czasopiśmie
Typ:
artykuły w czasopismach
Opublikowano w:
The North African Journal of Food and Nutrition Research nr 7, strony 1 - 8,
ISSN: 2588-1582
Język:
angielski
Rok wydania:
2023
Opis bibliograficzny:
Ayouaz S., Koss-Mikołajczyk I., Adjeroud-Abdellatif N., Bartoszek-Pączkowska A., Arab R., Mouhoubi K., Aji Muhammad D. R., Nur D. L., Madani K.: Anticarcinogenic and antioxidant activities of leaves and flowers hydroalcoholic extracts of Nerium oleander L.: PCA analysis and phytochemical content by FTIR spectroscopy// 19th Century music -,iss. 15 (2023), s.1-8
DOI:
Cyfrowy identyfikator dokumentu elektronicznego (otwiera się w nowej karcie) 10.51745/najfnr.7.15.1-8
Źródła finansowania:
  • Publikacja bezkosztowa
Weryfikacja:
Politechnika Gdańska

wyświetlono 116 razy

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