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Application of adjusted subpixel method (ASM) in HRCT measurements of the bronchi in bronchial asthma patients and healthy individuals
Abstrakt
Background: Recently, we described a model system which included corrections of high-resolution computedtomography (HRCT) bronchial measurements based on the adjusted subpixel method (ASM).Objective: To verify the clinical application of ASM by comparing bronchial measurements obtained bymeans of the traditional eye-driven method, subpixel method alone and ASM in a group comprised ofbronchial asthma patients and healthy individuals.Methods: The study included 30 bronchial asthma patients and the control group comprised of 20 volunteerswith no symptoms of asthma. The lowest internal and external diameters of the bronchialcross-sections (ID and ED) and their derivative parameters were determined in HRCT scans using: (1)traditional eye-driven method, (2) subpixel technique, and (3) ASM.Results: In the case of the eye-driven method, lower ID values along with lower bronchial lumen area andits percentage ratio to total bronchial area were basic parameters that differed between asthma patientsand healthy controls. In the case of the subpixel method and ASM, both groups were not significantlydifferent in terms of ID. Significant differences were observed in values of ED and total bronchial area withboth parameters being significantly higher in asthma patients. Compared to ASM, the eye-driven method overstated the values of ID and ED by about 30% and 10% respectively, while understating bronchial wall thickness by about 18%.Conclusions: Results obtained in this study suggest that the traditional eye-driven method of HRCTbasedmeasurement of bronchial tree components probably overstates the degree of bronchial patencyin asthma patients.
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Informacje szczegółowe
- Kategoria:
- Publikacja w czasopiśmie
- Typ:
- artykuł w czasopiśmie wyróżnionym w JCR
- Opublikowano w:
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EUROPEAN JOURNAL OF RADIOLOGY
nr 81,
strony 379 - 3830,
ISSN: 0720-048X - Język:
- angielski
- Rok wydania:
- 2012
- Opis bibliograficzny:
- Mincewicz G., Rumiński J., Krzykowski G.: Application of adjusted subpixel method (ASM) in HRCT measurements of the bronchi in bronchial asthma patients and healthy individuals// EUROPEAN JOURNAL OF RADIOLOGY. -Vol. 81, nr. iss. 2 (2012), s.379-3830
- DOI:
- Cyfrowy identyfikator dokumentu elektronicznego (otwiera się w nowej karcie) 10.1016/j.ejrad.2010.12.033
- Weryfikacja:
- Politechnika Gdańska
wyświetlono 102 razy
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