Filtry
wszystkich: 3407
wybranych: 1282
-
Katalog
Filtry wybranego katalogu
wyświetlamy 1000 najlepszych wyników Pomoc
Wyniki wyszukiwania dla: personalized cancer medicine
-
Sulforaphane inhibits growth of phenotypically different breast cancer cells
Publikacja -
Nuclear quantum effects in a HIV/cancer inhibitor: The case of ellipticine
Publikacja -
Pemphigus foliaceus in a patient with skin cancer with metastases to lymph nodes
Publikacja -
VEGF – targeted therapy for the treatment of cervical cancer – literature review
Publikacja -
Analysis of 5-Methylcytosine in DNA of Breast and Colon Cancer Tissues
Publikacja -
Biological Effects of Cold Atmospheric Pressure Plasma on Skin Cancer
Publikacja -
The p53-mediated cytotoxicity of photodynamic therapy of cancer: Recent advances
Publikacja -
Clinical Relevance of Circulating Tumor Cells in Prostate Cancer Management
Publikacja -
C-reactive Protein as a Diagnostic and Prognostic Factor of Endometrial Cancer
Publikacja -
The effects of RNA editing in cancer tissue at different stages in carcinogenesis
Publikacja -
Bladder cancer detection using a peptide substrate of the 20S proteasome
Publikacja -
Extracellular miRNAs as Biomarkers of Head and Neck Cancer Progression and Metastasis
Publikacja -
C-reactive protein as a diagnostic and prognostic factor of endometrial cancer
Publikacja -
Notch signalling pathway as an oncogenic factor involved in cancer development
Publikacja -
The role of Snail1 transcription factor in colorectal cancer progression and metastasis
Publikacja -
The ICTBioMed NCIP Hub: Cancer research in a science gateway consortium
Publikacja -
Metabolic profiling of pteridines for determination of potential biomarkers in cancer diseases
Publikacja -
Comparison of Pteridine Normalization Methods in Urine for Detection of Bladder Cancer
Publikacja -
The Role of miRNA-7 in the Biology of Cancer and Modulation of Drug Resistance
Publikacja -
Synthesis, molecular structure, and metabolic stability of new series of N' -(2-alkylthio-4-chloro-5-methylbenzenesulfonyl)-1-(5-phenyl-1 H -pyrazol-1-yl)amidine as potential anti-cancer agents
PublikacjaA series of new N'-(2-alkylthio-4-chloro-5-methylbenzenesulfonyl)-1-(5-phenyl-1H-pyrazol-1-yl)amidine derivatives have been synthesized and evaluated in vitro by MTT assays for their antiproliferative activity against cell lines of colon cancer HCT-116, cervical cancer HeLa and breast cancer MCF-7. The studied compounds display selective activity mainly against HCT-116 and HeLa cells. Thus, five compounds show selective cytotoxic...
-
Enhanced Activity of P4503A4 and UGT1A10 Induced by Acridinone Derivatives C-1305 and C-1311 in MCF-7 and HCT116 Cancer Cells: Consequences for the Drugs’ Cytotoxicity, Metabolism and Cellular Response
PublikacjaActivity modulation of drug metabolism enzymes can change the biotransformation of chemotherapeutics and cellular responses induced by them. As a result, drug-drug interactions can be modified. Acridinone derivatives, represented here by C-1305 and C-1311, are potent anticancer drugs. Previous studies in non-cellular systems showed that they are mechanism-based inhibitors of cytochrome P4503A4 and undergo glucuronidation via UDP-glucuronosyltranspherase...
-
Stage I non-small-cell lung cancer: long-term results of lobectomy versus sublobar resection from the Polish National Lung Cancer Registry†
Publikacja -
Extracellular matrix metalloproteinase inducer (EMMPRIN) expression correlates positively with active angiogenesis and negatively with basic fibroblast growth factor expression in epithelial ovarian cancer
Publikacja -
Physiological Biomarkers Assessed by Low‐Tech Exercise Tests Predict Complications and Overall Survival in Patients Undergoing Pneumonectomy Due to Lung Cancer
PublikacjaDue to its debilitating character pneumonectomy this is last‐resort procedure. Preoperative results of the 6‐min walking test (6MWT) help to identify high risk of postoperative complications and increased mortality in patients undergoing lobectomy for lung cancer. The aim of the study was to validate the value of 500 m in 6MWT as an indicator, which differentiates risk of complications in patients undergoing pneumonectomy. 125...
-
The Influence of Antitumor Unsymmetrical Bisacridines on 3D Cancer Spheroids Growth and Viability
PublikacjaThe culture of 3D spheroids is a promising tool in drug development and testing. Recently, we synthesized a new group of compounds, unsymmetrical bisacridines (UAs), which exhibit high cytotoxicity against various human cell lines and antitumor potency against several xenografts. Here, we describe the ability of four UAs—C-2028, C-2041, C-2045, and C-2053—to influence the growth of HCT116 and H460 spheres and the viability of HCT116...
-
Cadmium, arsenic, selenium and iron– Implications for tumor progression in breast cancer
Publikacja -
Metachronous adenocarcinoma in a gastric tube after radical surgery for oesophageal cancer
Publikacja -
A common nonsense mutation of the BLM gene and prostate cancer risk and survival
Publikacja -
Breast Cancer Heterogeneity Investigation: Multiple k-Means Clustering Approach
Publikacja -
Molecular Profiling for Predictors of Radiosensitivity in Patients with Breast or Head-and-Neck Cancer
Publikacja -
Erratum to: Sulforaphane inhibits growth of phenotypically different breast cancer cells
Publikacja -
Clinical Implications of mTOR Expression in Papillary Thyroid Cancer—A Systematic Review
Publikacja -
Inhibitory mikrotubul w terapii przeciwnowotworowej = Inhibitors of microtubule in cancer therapy
PublikacjaW artykule opisano inhibitory mikrotubul, różnorodne związki chemiczne, znajdujące się w zaawansowanych przedklinicznych i wstępnych badaniach klinicznych. Pośród nich na uwagę zasługują półsyntetyczne analogi taksolu, substancje pochodzenia naturalnego, takie jak: epotilony, kombretastatyny, kolchinoidy, dolastatyny oraz syntetyczne związki o niskim ciężarze czasteczkowym: heterokombretastatyny, sulfonamidy, fenostatyny, pochodne...
-
Radiation-Induced Changes in Serum Lipidome of Head and Neck Cancer Patients
Publikacja -
Mixture model of NMR - its application to diagnosis and treatment of brain cancer
Publikacja -
Oxidative DNA damage in cancer patients: a cause or a consequence of the disease development?
Publikacja -
K-ras gene mutation as an early prognostic marker of colon cancer
Publikacja -
The significance of lumican expression in ovarian cancer drug-resistant cell lines
Publikacja -
Diagnostic potential for a serum miRNA neural network for detection of ovarian cancer
Publikacja -
Prognostic factors in postoperative radiotherapy for prostate cancer – tertiary center experience
Publikacja -
Inhibition of protein glycosylation reverses the MDR phenotype of cancer cell lines
Publikacja -
Pharmacokinetics and pharmacodynamics of propofol in cancer patients undergoing major lung surgery
Publikacja -
Influence of Transurethral Resection of Bladder Cancer on Sexual Function, Anxiety, and Depression
Publikacja -
New data on antihypertensive drugs and risk of cancer: should we worry?
Publikacja -
Urinary metabolomic signature of muscle-invasive bladder cancer: A multiplatform approach
Publikacja -
The Influence of The Light-Activated Titania P25 on Human Breast Cancer Cells
Publikacja -
Radiotherapy-related changes in serum proteome patterns of head and neck cancer patients; the effect of low and medium doses of radiation delivered to large volumes of normal tissue
Publikacja -
Improved cytotoxicity and preserved level of cell death induced in colon cancer cells by doxorubicin after its conjugation with iron-oxide magnetic nanoparticles
PublikacjaA promising strategy for overcoming the problem of limited efficacy in antitumor drug delivery and in drug release is the use of a nanoparticle-conjugated drug. Doxorubicin (Dox) anticancer chemotherapeutics has been widely studied in this respect, because of severe cardiotoxic side effects. Here, we investigated the cytotoxic effects, the uptake process, the changes in cell cycle progression and the cell death processes in the...
-
Differential Response of MDA-MB-231 and MCF-7 Breast Cancer Cells to In Vitro Inhibition with CTLA-4 and PD-1 through Cancer-Immune Cells Modified Interactions
Publikacja -
Altered circadian genes expression in breast cancer tissue according to the clinical characteristics
Publikacja