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wszystkich: 133
wybranych: 115
Wyniki wyszukiwania dla: BIOMARKERS, CARDIOVASCULAR DISEASE, HYPERTENSION, MITOCHONDRIAL DNA, SEX, TMAO
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Mitochondrial DNA copy number and trimethylamine levels in the blood: New insights on cardiovascular disease biomarkers
PublikacjaAmong cardiovascular disease (CVD) biomarkers, the mitochondrial DNA copy number (mtDNAcn) is a promising candidate. A growing attention has been also dedicated to trimethylamine-N-oxide (TMAO), an oxidative derivative of the gut metabolite trimethylamine (TMA). With the aim to identify biomarkers predictive of CVD, we investigated TMA, TMAO, and mtDNAcn in a population of 389 coronary artery disease...
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Gender-Related Differences in Trimethylamine and Oxidative Blood Biomarkers in Cardiovascular Disease Patients
PublikacjaGender differences in the burden of cardiovascular disease (CVD) have been observed worldwide. In this study, plasmatic levels of trimethylamine (TMA) and blood oxidative biomarkers have been evaluated in 358 men (89 controls and 269 CVD patients) and 189 women (64 control and 125 CVD patients). The fluorescence technique was applied to determine erythrocyte membrane fluidity using 1,6-diphenyl-1,3,5-hexatriene (DPH) and Laurdan,...
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Trimethylamine N-oxide and the reverse cholesterol transport in cardiovascular disease: a cross-sectional study
PublikacjaThe early atherosclerotic lesions develop by the accumulation of arterial foam cells derived mainly from cholesterol-loaded macrophages. Therefore, cholesterol and cholesteryl ester transfer protein (CETP) have been considered as causative in atherosclerosis. Moreover, recent studies indicate the role of trimethylamine N-oxide (TMAO) in development of cardiovascular disease (CVD). The current study aimed to investigate the association...
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Pet Ownership and the Risk of Arterial Hypertension and Cardiovascular Disease
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Mitochondrial DNA levels in Huntington disease leukocytes and dermal fibroblasts
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Naturally occurring mitochondrial DNA heteroplasmy in the MRL mouse
PublikacjaThe MRL/MpJ mouse is an inbred laboratory strain of Mus musculus, known to exhibit enhanced autoimmunity, increased wound healing, and increased regeneration properties. We report the full-length mitochondrial DNA (mtDNA) sequence of the MRL mouse (Accession # EU450583), and characterize the discovery of two naturally occurring heteroplasmic sites. The first is a T3900C substitution in the TpsiCloop of the tRNA methionine gene...
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2-Methoxyestradiol and Hydrogen Peroxide as Promising Biomarkers in Parkinson’s Disease
PublikacjaEstrogens function in numerous physiological processes including controlling brain cell growth and differentiation. 2-Meth- oxestradiol (2-ME2), a 17β-estradiol (E2) metabolite, is known for its anticancer effects as observed both in vivo and in vitro. 2-ME2 affects all actively dividing cells, including neurons. The study aimed to determine whether 2-ME2 is a potentially cancer-protective or rather neurodegenerative agent in a...
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Hypertension and cardiovascular disease in women: Progress towards better understanding of gender‐specific differences?
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Depression and anxiety in cardiovascular disease
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An appropriate SCORE to assess cardiovascular risk in hypertension?
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Arterial stiffness, central hemodynamics, and cardiovascular risk in hypertension
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Impact of abdominal obesity on the frequency of hypertension and cardiovascular disease in Poland – Results from the IDEA study (International Day for the Evaluation of Abdominal Obesity)
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Are advanced glycation end-products specific biomarkers for Alzheimer's disease?
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Managing comorbid cardiovascular disease and sleep apnea with pharmacotherapy
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EDITORIALHypertension and cardiovascular disease: Is arterial stiffness the heart of the matter?
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Plasma Lipid Composition and Risk of Developing Cardiovascular Disease
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cGMP level in idiopathic Parkinson’s disease patients with and without cardiovascular disease – A pilot study
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Identification of Mitochondrial DNA (NUMTs) in the Nuclear Genome of Daphnia magna
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Oxidative stress in humans: validation of biomarkers of DNA damage
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Impaired baroreflex sensitivity as a potential marker of cardiovascular risk in hypertension
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Cardiovascular Function in Obstructive Sleep Apnea Patients with Controlled Hypertension
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Proteomic and lipidomic biomarkers in the diagnosis and progression of inflammatory bowel disease – a review
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The polypill: an emerging treatment alternative for secondary prevention of cardiovascular disease
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Mitochondrial DNA of Anisakis simplex S.S. as a Potential Tool for Differentiating Populations
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Molecular differences in mitochondrial DNA genomes of dogs with malignant mammary tumours
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Analysis of differences in the stability of proteins encoded in mitochondrial DNA of model organisms
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Association of Oral Status and Early Primary Hypertension Biomarkers among Children and Adolescents
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Women’s health, cardiovascular risk and hypertension: the perspective still needs to improve
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Comparative Analysis of CpG Sites and Islands Distributed in Mitochondrial DNA of Model Organisms
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Altered levels of circulating nuclear and mitochondrial DNA in patients with Papillary Thyroid Cancer
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Ancient mitochondrial DNA and the genetic history of Eurasian beaver (Castor fiber) in Europe
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Hypertension and coronary artery disease: Mechanistic insights and therapeutic challenges
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European Society of Hypertension Working Group on Obesity: obesity drugs and cardiovascular outcomes
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SCORE model underestimates cardiovascular risk in hypertensive patients: Results of the Polish Hypertension Registry
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A response to “Cardiovascular disease and obstructive sleep apnea: an underappreciated role for increased platelet activity?”
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Oxidatively Damaged DNA/Oxidative Stress in Children with Celiac Disease
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Relationship between selected DNA polymorphisms and coronary artery disease complications
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Oxidative DNA damage in cancer patients: a cause or a consequence of the disease development?
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Add-On Therapy with a Nighttime Dose of Doxazosin in Patients with Uncontrolled Hypertension: Effects on Autonomic Modulation of the Cardiovascular System
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Combination therapy in the management of hypertension — current problem in Poland. Expert consensus statement of the Polish Society of Hypertension and Polish Cardiac Society Working Group on Cardiovascular Pharmacotherapy
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Single-pill combinations (SPCs) and treatment of arterial hypertension in Poland. Expert consensus statement of the Polish Society of Hypertension and Polish Cardiac Society Working Group on Cardiovascular Pharmacotherapy
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Increased time varying heart rate and cardiovascular risk in hypertension – Benefit of selective I(f)channel inhibitor?
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Genetic risk factors influence nighttime blood pressure and related cardiovascular complications in patients with coronary heart disease
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Vitamin D Receptor Gene Polymorphism and Vitamin D Status in Population of Patients with Cardiovascular Disease—A Preliminary Study
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New 2017 American Heart Association and American College of Cardiology guideline for hypertension in the adults: major paradigm shifts, but will they help to fight against the hypertension disease burden?
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Oxidative stress and oxidative DNA damage is characteristic for mixed Alzheimer disease/vascular dementia
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Repeated bouts of exhaustive exercise increase circulating cell free nuclear and mitochondrial DNA without development of tolerance in healthy men
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Endogenously generated DNA nucleobase modifications source, and significance as possible biomarkers of malignant transformation risk, and role in anticancer therapy
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The Health Outcomes Prevention and Evaluation 4 (HOPE 4) project: A successful community-based intervention to lower cardiovascular risk in people with hypertension
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Does abdominal obesity have a similar impact on cardiovascular disease and diabetes? A study of 91 246 ambulant patients in 27 European Countries
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