Wyniki wyszukiwania dla: THERMAL DESCRIPTORS

• Solubility of dapsone in deep eutectic solvents: Experimental analysis, molecular insights and machine learning predictions

  Publikacja

  • T. Jeliński
  • M. Przybyłek
  • R. Różalski
  • P. Cysewski

  - Polimery w Medycynie - Rok 2024

  Background. Dapsone (DAP) is an anti-inflammatory and antimicrobial active pharmaceutical ingredient used to treat, e.g., AIDS-related diseases. However, low solubility is a feature hampering its efficient use. Objectives. First, deep eutectic solvents...

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• Intermolecular Interactions of Edaravone in Aqueous Solutions of Ethaline and Glyceline Inferred from Experiments and Quantum Chemistry Computations

  Publikacja

  • P. Cysewski
  • T. Jeliński
  • M. Przybyłek

  - MOLECULES - Rok 2023

  Edaravone, acting as a cerebral protective agent, is administered to treat acute brain infarction. Its poor solubility is addressed here by means of optimizing the composition of the aqueous choline chloride (ChCl)-based eutectic solvents prepared with ethylene glycol (EG) or glycerol (GL) in the three different designed solvents compositions. The slurry method was used for spectroscopic solubility determination in temperatures...

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