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Wyniki wyszukiwania dla: HUMAN TUMOR XENOGRAFTS
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Reactive oxygen species (ROS) production in human peripheral blood neutrophils exposedin vitroto static magnetic field
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Expression Profile of Genes Regulating Steroid Biosynthesis and Metabolism in Human Ovarian Granulosa Cells—A Primary Culture Approach
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The motif EXEXXXL in the cytosolic tail of the secretory human proprotein convertase PC7 regulates its trafficking and cleavage activity
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Comparison the heat load as the results of tests on human subject in a hot environment with the results obtained from numerical simulation
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Development of the first internally-quenched fluorescent substrates of human cathepsin C: The application in the enzyme detection in biological samples
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New Selective Peptidyl Di(chlorophenyl) Phosphonate Esters for Visualizing and Blocking Neutrophil Proteinase 3 in Human Diseases
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The importance of evaluating metal exposure and predicting human health risks in urban–periurban environments influenced by emerging industry
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Modulatory Effects of Curcumin and Tyrphostins (AG494 and AG1478) on Growth Regulation and Viability of LN229 Human Brain Cancer Cells
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Synthesis of isomeric, oxathiolone fuded chalcones and comparison of their activity toward various microorganisms and human cancer cell lines
PublikacjaIzomeryczne oksationolowe sprzężone chalkony otrzymano w wyniku kondensacji odpowiedniego acetylobenzo[1,3]oksatiolo-2-onu z aldehydem benzoesowym w środowisku kwaśnym. Określono aktywność cytotoksyczną otrzymanych związków wobec komórek linii HeLa, przeciwbakteryjną wobec Micrococcus luteus, Staphylococcus aureus, Salmonella typhimurium, Escherichia coli i Proteus vulgaris, przeciwgrzybową wobec Candida albicans i tuberkulostatyczną...
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Acid-catalysed synthesis of oxathiolone fused chalkones. Comparison of their activity toward various microrganisms and human cancer lines
PublikacjaOtrzymano podstawione pochodne oksationolowych sprzężonych chalkonów w wyniku kondensacji 4-acetylo-5-metoksy-2-0ksobenz[1,3]oksatiolu z aldehydem benzoesowym w środowisku kwaśnym. Badano właściwości biologiczne otrzymanych związków. Trzy z otrzymanych pochodnych wykazały umiarkowaną aktywność wobec komórek HeLa, dwa były aktywne wobec Micrococcus luteus i Staphylococcus aureus, a jeden wobec Mycobacterium tuberculosis.
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The cellular response of human hepatoma cells with different expression of CYP3A4 isoenzyme to treatment with triazoloacridinone derivative C-1305
PublikacjaCelem badań było określenie w jaki sposób ekspresja enzymów odpowiedzialnych za metabolizm pochodnej triazoloakrydonu C-1305 wpływa na odpowiedź komórek ludzkiego raka wątroby HepG2 i Hep3A4. W komórkach HepG2 triazoloakrydon C-1305 indukuje proces starzenia, podczas gdy w przypadku linii Hep3A4, komórki ulegają apoptozie oraz nekrozie.
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Imidazoacridinone antitumor agent, c-1311, as a selective mechanism-based inactivator of human recombinant cytochrome P450 1A2
PublikacjaPrzedmiotem badań była przeciwnowotworowa pochodna imidazoakrydonu, C-1311, która pod nazwą Symadex R, znajduje się aktualnie w II fazie badań klinicznych. Wcześniejsze wyniki pozwoliły stwierdzić, że związek ten jest selektywnym inhibitorem niektórych enzymów cytochromowych. Podjęto zatem próbę wyjaśnienia mechanizmu inhibicji izoenzymów cytochromu P450 przez C-1311. Wykazano, że utrata aktywności katalitycznej obu izoenzymów...
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Acute hypoxia diminishes the relationship between blood pressure and subarachnoid space width oscillations at the human cardiac frequency
PublikacjaAcute hypoxia exerts strong effects on the cardiovascular system. Heart-generated pulsatile cerebrospinal fluid motion is recognised as a key factor ensuring brain homeostasis. We aimed to assess changes in heart-generated coupling between blood pressure and subarachnoid space width oscillations during hypoxic exposure.
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Wpływ zmiany parametrów geometrycznych na wydajność i efektywność protezy zastawki aortalnej Human Aortic Bioprosthesis
PublikacjaW pracy wykazano na podstawie rezultatów badań in vitro, że konstrukcja wykonana z nanocelulozy bakteryjnej, posiada wszelkie cechy protezy zastawki aortalnej możliwe do wykazania na drodze ww. badań oraz że określone cechy geometrii protezy wpływają na jej efektywność i funkcjonalność. W szczególności, w pracy przedstawiono wyniki badań in vitro trzech modeli konstrukcji protezy zastawki aortalnej, oznaczonych M2, M4’ i M4. Badania...
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Bezpieczeństwo człowieka na statku w świetle obowiązujących przepisów = Human safety on vessels in accordance with actual regulations
PublikacjaStatek jest przykładem miejsca, w którym ochrona człowieka narzuca szczególne wymagania. Wiąże się ona z relacjami przestrzennymi między rozwiązaniami technicznymi statku, gdzie stosowanie nowych rozwiązań wspomaganych elektroniką powoduje, że statki stają się coraz szybsze, bezpieczniejsze, zdolne do transportu różnego rodzaju ładunków na coraz większe odległości a stopniem odporności człowieka i możliwościami dostosowania się...
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Application of SSB-like protein from Thermus aquaticus in multiplex PCR of human Y-STR markers identification
PublikacjaW tej publikacji prezentujemy zastosowanie białka SSB-podobnego Thermus aquaticus (TaqSSB) w reakcji multiplex PCR w celu identyfikacji markerów ludzkiego Y-STR. Wykorzystanie termostabilnego białka TaqSSB chroni lub redukuje tworzenie przez startery struktur dimerycznych, które powodują hamowanie hybrydyzacji starterów do badanego DNA i redukują ilość starterów dostępnych w reakcji PCR.
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A novel nucleotide found in human erythrocytes, 4-pyridone-3-carboxamide-1-beta-D-ribonucleoside triphosphate
PublikacjaZidentyfikowano nowy, nieznany nukleotyd, występujący w erytrocytach osób chorych na przewlekłą niewydolność nerek, w stężeniu porównywalnym do zawartości ATP. Nukleotyd ten wyizolowano chromatograficznie, a jego strukturę określono jako trójfosforan 4-piridono-3-karboksyamido-1-b-D-rybonukleozydu, na podstawie danych spektralnych UV, MS, IR i NMR.
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Mixed germ cell tumor - Male, 36 - Tissue image [6270730022331891]
Dane BadawczeThis is the histopathological image of TESTIS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Mixed germ cell tumor - Male, 36 - Tissue image [6270730022335921]
Dane BadawczeThis is the histopathological image of TESTIS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Mixed germ cell tumor - Male, 36 - Tissue image [6270730022339671]
Dane BadawczeThis is the histopathological image of TESTIS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Mixed germ cell tumor - Male, 36 - Tissue image [6270730022338081]
Dane BadawczeThis is the histopathological image of TESTIS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Mixed germ cell tumor - Male, 36 - Tissue image [6270730022338731]
Dane BadawczeThis is the histopathological image of TESTIS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Mixed germ cell tumor - Male, 36 - Tissue image [6270730022333921]
Dane BadawczeThis is the histopathological image of TESTIS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Serous borderline tumor, NOS - Female, 26 - Tissue image [9270729565543431]
Dane BadawczeThis is the histopathological image of OVARY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Tenosynovial giant cell tumor, localised - Male, 9 - Tissue image [6300730028268441]
Dane BadawczeThis is the histopathological image of OTHER AND ILL-DEFINED SITES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Tenosynovial giant cell tumor, localised - Male, 9 - Tissue image [6300730028269641]
Dane BadawczeThis is the histopathological image of OTHER AND ILL-DEFINED SITES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Tenosynovial giant cell tumor, localised - Male, 9 - Tissue image [6300730028263151]
Dane BadawczeThis is the histopathological image of OTHER AND ILL-DEFINED SITES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Mixed germ cell tumor - Male, 25 - Tissue image [6180730013782811]
Dane BadawczeThis is the histopathological image of TESTIS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Mixed germ cell tumor - Male, 25 - Tissue image [6180730013782951]
Dane BadawczeThis is the histopathological image of TESTIS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Mixed germ cell tumor - Male, 25 - Tissue image [6180730013781991]
Dane BadawczeThis is the histopathological image of TESTIS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Mixed germ cell tumor - Male, 25 - Tissue image [6180730013786071]
Dane BadawczeThis is the histopathological image of TESTIS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Mixed germ cell tumor - Male, 25 - Tissue image [7040247104932271]
Dane BadawczeThis is the histopathological image of TESTIS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Mixed germ cell tumor - Male, 25 - Tissue image [6180730013785481]
Dane BadawczeThis is the histopathological image of TESTIS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Tenosynovial giant cell tumor, localised - Female, 33 - Tissue image [618073001378491]
Dane BadawczeThis is the histopathological image of OTHER AND ILL-DEFINED SITES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Tenosynovial giant cell tumor, localised - Male, 47 - Tissue image [6180730013783671]
Dane BadawczeThis is the histopathological image of OTHER AND ILL-DEFINED SITES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Tenosynovial giant cell tumor, localised - Male, 47 - Tissue image [6180730013787791]
Dane BadawczeThis is the histopathological image of OTHER AND ILL-DEFINED SITES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Tenosynovial giant cell tumor, localised - Male, 47 - Tissue image [6180730013782101]
Dane BadawczeThis is the histopathological image of OTHER AND ILL-DEFINED SITES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Tenosynovial giant cell tumor, localised - Male, 47 - Tissue image [6180730013782731]
Dane BadawczeThis is the histopathological image of OTHER AND ILL-DEFINED SITES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Tenosynovial giant cell tumor, localised - Female, 33 - Tissue image [6180730013781011]
Dane BadawczeThis is the histopathological image of OTHER AND ILL-DEFINED SITES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Tenosynovial giant cell tumor, localised - Male, 47 - Tissue image [6180730013785501]
Dane BadawczeThis is the histopathological image of OTHER AND ILL-DEFINED SITES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Tenosynovial giant cell tumor, localised - Female, 33 - Tissue image [6180730013785201]
Dane BadawczeThis is the histopathological image of OTHER AND ILL-DEFINED SITES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Tenosynovial giant cell tumor, localised - Male, 47 - Tissue image [6180730013783801]
Dane BadawczeThis is the histopathological image of OTHER AND ILL-DEFINED SITES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Tenosynovial giant cell tumor, localised - Female, 33 - Tissue image [6180730013787311]
Dane BadawczeThis is the histopathological image of OTHER AND ILL-DEFINED SITES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Tenosynovial giant cell tumor, localised - Female, 33 - Tissue image [7040247104939001]
Dane BadawczeThis is the histopathological image of OTHER AND ILL-DEFINED SITES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Tenosynovial giant cell tumor, diffuse - Male, 37 - Tissue image [6190730017347221]
Dane BadawczeThis is the histopathological image of CONNECTIVE, SUBCUTANEOUS AND OTHER SOFT TISSUES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Tenosynovial giant cell tumor, diffuse - Male, 37 - Tissue image [6190730017345651]
Dane BadawczeThis is the histopathological image of CONNECTIVE, SUBCUTANEOUS AND OTHER SOFT TISSUES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Tenosynovial giant cell tumor, diffuse - Male, 37 - Tissue image [6190730017347871]
Dane BadawczeThis is the histopathological image of CONNECTIVE, SUBCUTANEOUS AND OTHER SOFT TISSUES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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A new MIC1-MAG1 recombinant chimeric antigen can be used instead of the Toxoplasma lysate antigen in the serodiagnosis of human toxoplasmosis
PublikacjaW niniejszej publikacji po raz pierwszy przedstawiono otrzymanie i oszacowanie przydatności diagnostycznej nowego chimerycznego antygenu MIC1-MAG1 Toxoplasma gondii do rozpoznawania toksoplazmozy u ludzi. Antygen chimeryczny MIC1-MAG1 został otrzymany jako białko fuzyjne zawierające dwie domeny oligohistydynowe na N- i C-końcu z użyciem systemu ekspresyjnego Escherichia coli. Po oczyszczeniu z wykorzystaniem metody chromatografii...