Wyniki wyszukiwania dla: DRUG ABUSE

• Disposition of Drugs of Abuse and Their Metabolites in Wastewater as a Method of the Estimation of Drug Consumption

  Publikacja

  • E. Daghir
  • M. J.

  - Current Drug Metabolism - Rok 2010

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• Integration of protein tethering in a rapid and label-free SERS screening platform for drugs of abuse

  Publikacja

  • S. Siddhanta
  • M. Wróbel
  • I. Barman

  - CHEMICAL COMMUNICATIONS - Rok 2016

  Surface enhanced Raman spectroscopy (SERS) has emerged as a promising technique for the rapid and ultrasensitive detection of molecular species such as drugs of abuse in biofluids. Yet, it remains a significant challenge to create a viable screening tool for multiple drug classes, owing to the lack of affinity of certain species for the SERS substrate and to the matrix interference in complex media. Here we report a protein tethering...

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• Current drug abuse reviews

  Czasopisma

  ISSN: 1874-4737

• AMERICAN JOURNAL OF DRUG AND ALCOHOL ABUSE

  Czasopisma

  ISSN: 0095-2990 , eISSN: 1097-9891

• Prenatal exposure to substance of abuse: A worldwide problem

  Publikacja

  • S. Narkowicz
  • J. Płotka-Wasylka
  • Ż. Polkowska
  • M. Biziuk
  • J. Namieśnik

  - ENVIRONMENT INTERNATIONAL - Rok 2013

  Substance abuse during pregnancy is an important public health issue affecting the mother and the growing infant. Preterm labor, miscarriage, abruption and postpartum hemorrhage are obstetric complications which have been associated with women who are dependent on abused substances. Moreover, women are also at an increased risk of medical problems such as poor nutrition, anemia, urinary tract infections as well as sexually transmitted...

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• Methods for Elucidation of DNA-Anticancer Drug Interactions and Their Applications in the Development of New Drugs

  Publikacja

  • M. Misiak
  • F. Mantegazza
  • G. Beretta

  - CURRENT PHARMACEUTICAL DESIGN - Rok 2016

  DNA damaging agents including anthracyclines, camptothecins and platinum drugs are among most frequently used drugs in the chemotherapeutic routine. Due to their relatively low selectivity for cancer cells, administration is associated with adverse side effects, whereas the inherent genotoxicity of these drugs is associated with risk of developing secondary cancers. Development of new drugs, which could be spared of these drawbacks...

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• Partner Abuse

  Czasopisma

  ISSN: 1946-6560 , eISSN: 1946-6579

• Substance Abuse

  Czasopisma

  ISSN: 0889-7077 , eISSN: 1547-0164

• Combining markers of nephrotoxicity and hepatotoxicity for improved monitoring and detection of chronic alcohol abuse

  Publikacja

  • E. Taracha
  • B. Habrat
  • S. Chrapusta
  • M. Lehner
  • A. Wisłowska
  • B. Woronowicz
  • M. Bogulas
  • J. Charewicz
  • C. Markuszewski
  • A. Płaźnik

  - CLINICAL CHEMISTRY AND LABORATORY MEDICINE - Rok 2006

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• Glutathione-mediated conjugation of anticancer drugs: an overview of reaction mechanisms and biological significance for drug detoxification and bioactivation.

  Publikacja

  • A. Potęga

  - MOLECULES - Rok 2022

  The effectiveness of many anticancer drugs depends on the creation of specific metabolites that may alter their therapeutic or toxic properties. One significant route of biotransformation is a conjugation of electrophilic compounds with reduced glutathione, which can be non-enzymatic and/or catalyzed by glutathione-dependent enzymes. Glutathione usually combines with anticancer drugs and/or their metabolites to form more polar...

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