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Wyniki wyszukiwania dla: gene disruption
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Gene set enrichment for reproducible science: comparison of CERNO and eight other algorithms
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Adaptive filtering of microarray gene expression data based on Gaussian mixture decomposition
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Proteins Structure Models in the Evaluation of Novel Variant (C.472_477del) in the MOCS2 Gene
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Optimised expression cassettes of hpt marker gene for biolistic transformation of Miscanthus sacchariflorus
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Genome-Wide DNA Methylation and Gene Expression in Patients with Indolent Systemic Mastocytosis
PublikacjaMastocytosis is a clinically heterogenous, usually acquired disease of the mast cells with a survival time that depends on the time of onset. It ranges from skin-limited to systemic disease, including indolent and more aggressive variants. The presence of the oncogenic KIT p. D816V gene somatic mutation is a crucial element in the pathogenesis. However, further epigenetic regulation may also affect the expression of genes that...
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The Relationship Between Gene Polymorphisms and Dipping Profile in Patients With Coronary Heart Disease
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Relationship between polymorphism in the CRH gene and the traits of body conformation of Salers cows
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The role of FNDC5 gene expression in irisin level changes accompanying thyroid pathologies
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Research Trends of Vitamin D Metabolism Gene Polymorphisms Based on a Bibliometric Investigation
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Association of ENAM gene single nucleotide polymorphisms with dental caries in Polish children
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The role of TGF superfamily gene expression in the regulation of folliculogenesis and oogenesis in mammals: a review
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Homocitrate synthase gene as a new molecular target in diagnostics of Candida spp. infections
PublikacjaNew potential molecular target which will be investigated during this research (homocitrate synthase gen) is the innovative target other than ribosomal DNA. This gene encodes enzyme present only in fungi and some Archaea what significantly increases specificity. It also reduces risk of contamination or influence of other factors (reaction with other DNA present in sample derived from bacteria or host cells) what excludes false...
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Justification of quasi-stationary approximation in models of gene expression of a self-regulating protein
PublikacjaWe analyse a model of Hes1 gene transcription and protein synthesis with a negative feedback loop. The effect of multiple binding sites in the Hes1 promoter as well as the dimer formation process are taken into account. We consider three, possibly different, time scales connected with: (i) the process of binding to/dissolving from a binding site, (ii) formation and dissociation of dimers, (iii) production and degradation of Hes1...
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TRNA-Leu (UUR) gene haplotypes observed in canine mammary gland tumours and its deleterious effect assessment according to the comparative analysis with TRNL1 human gene
Dane BadawczeThe aetiology and pathogenesis of many canine tumours are likely to be similar to cancers found in humans. This study aimed to present a plausible link between changes in tRNA-Leu (UUR) gene and the carcinogenesis process in dogs with mammary gland tumours. The whole mitochondrial DNA (mtDNA) isolated from blood and tumour tissues of 13 dogs with malig-nant...
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Cahiers du Genre
Czasopisma -
DEVELOPMENT GENES AND EVOLUTION
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GENES & GENETIC SYSTEMS
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Genre Sexualite & Societe
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GENES BRAIN AND BEHAVIOR
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How to eliminate the formation of chlorogenic acids artefacts during plants analysis? Sea sand disruption method (SSDM) in the HPLC analysis of chlorogenic acids and their native derivatives in plants
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Evaluation of the Possibility of Using Hydroponic Cultivations for the Removal of Pharmaceuticals and Endocrine Disrupting Compounds in Municipal Sewage Treatment Plants
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Natural/bio-based sorbents as greener extractive materials for endocrine disrupting compounds in samples of different matrix composition
PublikacjaEndocrine-disrupting compounds (EDCs) are a group of chemicals that interfere with the endocrine system, leading to adverse effects on human health and the environment. Increasing concerns over the EDCs presence in various environmental compartments has driven the search for greener extraction materials. Recently, the use of polymers of natural origin (biopolymers) has been demonstrated to be an effective and promising research...
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Development of a liquid chromatography–tandem mass spectrometryprocedure for determination of endocrine disrupting compounds infish from Mediterranean rivers
PublikacjaA new, sensitive and rapid method based on QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe)approach followed by ultra high performance liquid chromatography coupled with tandem mass spec-trometry (UHPLC–MS/MS) was developed for the determination of nineteen endocrine disruptors (EDCs)and related compounds belonging to different classes in various fish species. Matrix effect on the analyti-cal performance was evaluated,...
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Prognostic Value of TOP2A Gene Amplification and Chromosome 17 Polysomy in Early Breast Cancer
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Molecular typing of Staphylococcus aureus based on PCR-RFLP of coa gene and RAPD analysis
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Sensitivity, Specificity and Prioritization of Gene Set Analysis When Applying Different Ranking Metrics
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Association between uridin diphosphate glucuronosylotranserase 1A1 (UGT1A1) gene polymorphism and neonatal hyperbilirubinemia
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Liver steatosis correlates with iron overload but not with HFE gene mutations in chronic hepatitis C
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Associations of ESR1 and ESR2 gene polymorphisms with metabolic syndrome and its components in postmenopausal women
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New, fast and cheap prediction tests for BRCA1 gene mutations identification in clinical samples.
PublikacjaDespite significant progress in cancer therapy, cancer is still the second cause of mortality in the world. The necessity to make quick therapeutic decisions forces the development of procedures allowing to obtain a reliable result in a quick and unambiguous manner. Currently, detecting predictive mutations, including BRCA1, is the basis for effectively treating advanced breast cancer. Here, we present new insight on gene mutation...
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Cellular and Gene Expression Response to the Combination of Genistein and Kaempferol in the Treatment of Mucopolysaccharidosis Type I
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TGF-β gene polimorphisms as risk factors for asthma control among clinic patients
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TGF-β gene polimorphisms as risk factors for asthma control among clinic patients.
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TGF-β gene polimorphisms as risk factors for asthma control among clinic patients.
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Graphene-encapsulated iron nanoparticles as a non-viral vector for gene delivery into melanoma cells
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Metabolic Gene Expression in the Muscle and Blood Parameters of Broiler Chickens Stimulated In Ovo with Synbiotics
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Morphogenesis-related gene-expression profile in porcine oocytes before and after in vitro maturation
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The effects of p53 gene inactivation on mutant proteome expression in a human melanoma cell model
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Gene Therapy Approaches to Prevent Corneal Graft Rejection: Where Do We Stand?
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Genetic and structural characterization of the growth hormone gene and protein from tench, Tinca tinca
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The carbon source-dependent pattern of antimicrobial activity and gene expression in Pseudomonas donghuensis P482
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Expression of Deinococcus geothermalis Trehalose Synthase Gene in Escherichia coli and Its Enzymatic Properties
PublikacjaA novel trehalose synthase gene from Deinococcus geothermalis (DSMZ 11300) containing 1,692 bp reading-frame encoding 564 amino acids was amplified using PCR. The gene was ligated into pET30Ek/LIC vector and expressed after isopropyl alfa-D-thiogalactopyranoside induction in Escherichia coli BL21(DE3)pLysS. The recombinant trehalose synthase (DgeoTreS) containing a His6 tag at the C-terminus was purified by metal affinity chromatography...
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Evolving gene regulatory networks controlling foraging strategies of prey and predators in an artificial ecosystem
PublikacjaCo-evolution of predators and prey is an example of an evolutionary arms race, leading in nature to selective pressures in positive feedback. We introduce here an artificial life ecosystem in which such positive feedback can emerge. This ecosystem consists of a 2-dimensional liquid environment and animats controlled by evolving artificial gene regulatory networks encoded in linear genomes. The genes in the genome encode chemical...
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Ceragenin CSA-13 as free molecules and attached to magnetic nanoparticle surfaces induce caspase-dependent apoptosis in human breast cancer cells via disruption of cell oxidative balance
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Daily diet containing canned products significantly increases serum concentrations of endocrine disruptor bisphenol A in young women
PublikacjaNowadays, exposure to environmental factors is considered to be one of the possible causes of several lifestyle diseases, such as obesity, type 2 diabetes, cardiovascular disease, and cancer. Particularly noteworthy are endocrine‑disrupting chemicals (EDCs), which affect the metabolism of hormones and interact with their receptors, thus exerting adverse health effects. One of the most ubiquitous EDC in daily life is bisphenol A...
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The Relationship between Gene Activity and Nitrous Oxide Production during Nitrification in Activated Sludge Systems
PublikacjaNitrite is an important factor which inhibits the first stage of the nitrification, the effect is stronger with the decrease of the DO concentrations. NO2- presence at concentration above 15 mg N – NO2 in the aeration tanks stimulates N2O production regardless of the DO concentration. The significant nirS gene induction, observed especially during the experiments with the nitrite addition indicates that N2O production is basically...
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HIF1A, EPAS1, and VEGFA: angiogenesis and hypoxia-related gene expression in endometrium and endometrial epithelial tumors
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p53 Gene status in relation to ex vivo chemosensitivity of non-small cell lung cancer
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A new potential mode of cardiorenal protection of KLOTHO gene variability in type 1 diabetic adolescents
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Antioxidative enzymes and expression of rbcL gene as tools to monitor heavy metal-related stress in plants
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