Natalia Łozińska - Publications - Bridge of Knowledge

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Year 2024
  • Bile conjugation and its effect on in vitro lipolysis of emulsions
    Publication

    - FOOD RESEARCH INTERNATIONAL - Year 2024

    Bile Salts (BS) are responsible for stimulating lipid digestion in our organism. Gut microbiota are responsible for the deconjugation process of primary conjugated to secondary unconjugated BS. We use two structurally distinct BS and characterize the rate of lipolysis as a compound parameter. A static in-vitro digestion model as well as meta-analysis of literature data has been performed to determine the most influential factors...

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Year 2021
  • Importance of Bile Composition for Diagnosis of Biliary Obstructions
    Publication

    - MOLECULES - Year 2021

    Determination of the cause of a biliary obstruction is often inconclusive from serum analysis alone without further clinical tests. To this end, serum markers as well as the composition of bile of 74 patients with biliary obstructions were determined to improve the diagnoses. The samples were collected from the patients during an endoscopic retrograde cholangiopancreatography (ERCP). The concentration of eight bile salts, specifically...

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  • Importance of Conjugation of the Bile Salt on the Mechanism of Lipolysis
    Publication

    We aim to advance the discussion on the significance of the conjugation of bile salts (BS) in our organism. We hypothesize that conjugation influences the rate of lipolysis. Since the rate of lipolysis is a compound parameter, we compare the effect of conjugation on four surface parameters, which contribute to the rate. Since deconjugation is due to gut microbiota, we hypothesize that microbiota may affect the rate of lipolysis....

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Year 2020
Year 2019

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