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The use of HPLC-Q-TOF-MS for comprehensive screening of drugs and psychoactive substances in hair samples and several “legal highs” products
Abstract
Non-targeted screening of drugs present in herbal products, known as “legal high” drugs and in hair as a biological matrix commonly used in toxicological investigations was accomplished with the use of high pressure liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (HPLC-Q-TOF-MS). In total, 25 and 14 therapeutical drugs and psychoactive substances/metabolites were detected in investigated hair samples and herbal products, respectively. We demonstrate that the HPLC-Q-TOF methodology seems to be a powerful tool in the qualitative analysis applied in identification of these designer drugs, thus enabling a laboratory to stay-up-to-date with the drugs that are being sold as legal high products on black market.
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- DOI:
- Digital Object Identifier (open in new tab) 10.1007/s00706-016-1773-z
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- Category:
- Articles
- Type:
- artykuł w czasopiśmie wyróżnionym w JCR
- Published in:
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MONATSHEFTE FUR CHEMIE
no. 147,
edition 8,
pages 1407 - 1414,
ISSN: 0026-9247 - Language:
- English
- Publication year:
- 2016
- Bibliographic description:
- Aszyk J., Kot-Wasik A.: The use of HPLC-Q-TOF-MS for comprehensive screening of drugs and psychoactive substances in hair samples and several “legal highs” products// MONATSHEFTE FUR CHEMIE. -Vol. 147, iss. 8 (2016), s.1407-1414
- DOI:
- Digital Object Identifier (open in new tab) 10.1007/s00706-016-1773-z
- Verified by:
- Gdańsk University of Technology
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