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Search results for: dna sequence recognition
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Ancient mitochondrial DNA and the genetic history of Eurasian beaver (Castor fiber) in Europe
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B26 Differential mitochondrial DNA levels in HD patients depending on the cell type
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Wpływ dodatku kwasu deoksyrybonukleinowego (DNA) na właściwości mechaniczne żeli żelatynowych
PublicationKwasy nukleinowe cieszą się coraz większym zainteresowaniem pod względem zastosowania ich w przemyśle farmaceutycznym, kosmetycznym oraz żywnościowym. Określono wpływ dodatku długo- i krótkołańcuchowych kwasów nukleinowych na właściwości mechaniczne żeli żelatynowych. Badania wykazały występowanie specyficznych interakcji pomiędzy żelatyną a kwasami nukleinowymi oraz pozwoliły na ocenę wpływu tych oddziaływań na twardość, kohezyjność,...
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C-1311 (Symadex), a potential anti-cancer drug, intercalates into DNA between A and G moieties. NMR-derived and MD-refined stereostructure of the d(GAGGCCTC) 2 :C-1311 complex
PublicationImidazoacridinone C-1311 (Symadex®) is an antitumor agent which has been recommended for Phase II clinical trials a few years ago. Previously, it was shown experimentally that during the initial stage of its action C-1311 forms stable intercalation complexes with DNA duplexes. Herein, a NMR-derived stereostructure of d(GAGGCCTC)2:C-1311 complex was reported. The ligand was found locating itself between A and G moieties, forming...
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CERVIX UTERI, Exocervix - Female, 46 - Cell image [4140730008823071]
Open Research DataThis is the histopathological image of CERVIX UTERI cell sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Moshi Shibie yu Rengong Zhineng/Pattern Recognition and Artificial Intelligence
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DNA-reactive anticancer imidazoacridinone C-1311 is a new inhibitor of hypoxia-inducible factor 1 alpha, vascular endothelial growth factor and tumor angiogenesis
PublicationHypoxia-inducible factor 1 (HIF-1) plays a critical role for tumor adaptation to hypoxia and promotes angiogenesis. Antitumor imidazoacridinone C-1311 is a DNA reactive topoisomerase II and FLT3 receptor tyrosine kinase inhibitor selected for phase II clinical trials for breast cancer. Here, we demonstrate the new mechanism of C-1311 action involving HIF-1a, vascular endothelial growth factor (VEGF) and angiogenesis as additional...
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Site-selective cation–π interaction as a way of selective recognition of the caesium cation using sumanene-functionalized ferrocenes
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A new phosphonium calix[4]arene for selective anion recognition: synthesis and studies in solution and in ion selective electrodes
PublicationZaprezentowana została synteza i charakteryzacja tetra (trifenylofosfoniowego) p-tert-butylkaliks[4]arenu 2. Oddziaływania z anionami były badane z użyciem (1)H oraz (31)P NMR i spektrofotometrii absorpcyjnej UV. Badania wykazały oddziaływania z anionami: CLO4-, I-, oraz SCN-. Selektywność jonoforu 2 badano również w membranowych elektrodach jonoselektywnych (ISE) PCV/o-NPOE. Elektroda zawierająca związek 2 generuje odpowiedź potencjometryczną...
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Oscillating water-oil-water liquid membrane systems for molecular recognition of substances belonging to diferent taste classes
PublicationBadano oscylacje róznicy potencjału elektrochemicznego miedzy fazami wodnymi. Jedna faza wodna zawiera kationowy lub anionowy surfaktant podczas gdy w drugiej fazie wodnej znajduje sie substancja odpowiedzialna za smak. Dwie fazy wodne sa rozdzielone faza olejową. Oscylacje były analizowane poprzez konstrukcje portretów fazowych uzywając metody opoznienia czasowego. Kształt portretów fazowych jest rozny dla oscylatorów z kationowym...
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Sample processing for DNA chip array-based analysis of enterohemorrhagic Escherichia coli (EHEC)
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A novel dual mode capacitor biosensor for real-time, label-free DNA detection
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Detection of bacteriophage infection and prophage induction in bacterial cultures by means of electric DNA chips
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Damage to Model DNA Fragments from Very Low-Energy (<1 eV) Electrons
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Cellular Turnover: A Potential Metabolic Rate–Driven Mechanism to Mitigate Accumulation of DNA Damage
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Influence of Selected Factors on the Survival Assessment and Detection of Giardia intestinalis DNA in Axenic Culture
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DNA variants in Helicobacter pylori infected patients with chronic gastritis, dysplasia and gastric cancer
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DNA Variants in Helicobacter Pylori Infected Patients with Chronic Gastritis, Dysplasia and Gastric Cancer
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Tracking Clonal Evolution of Multiple Myeloma Using Targeted Next-Generation DNA Sequencing
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Mass Spectrometry-Based Analysis of DNA Modifications: Potential Applications in Basic Research and Clinic
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Endogenous oxidative DNA base modifications analysed with repair enzymes and GC/MS technique
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Preparation of Internal Standards for 2D-UPLC-MS/MS Quantification of Noncanonical DNA Bases
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Supplementation with antioxidant vitamins prevents oxidative modification of DNA in lymphocytes of HIV-infected patients
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Melatonin as a major skin protectant: from free radical scavenging to DNA damage repair
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Aberrant repair of etheno–DNA adducts in leukocytes and colon tissue of colon cancer patients
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Oxidative stress and oxidative DNA damage is characteristic for mixed Alzheimer disease/vascular dementia
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Preliminary studies on DNA retardation by MutS applied to the detection of point mutations in clinical samples
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Population dynamics of Baltic herring since the Viking Age revealed by ancient DNA and genomics
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One tube mutation detection using sensitive fluorescent dyeing of MutS protected DNA
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Bio-inspired Decisional DNA in Machinas and other Man-made Systems: The Way Forward
PublicationArtificial bio-inspired intelligent techniques and systems supporting smart, knowledge-based solutions of real world problems which are currently researched very extensively by research teams around the world, have enormous potential to enhance automation of decision making and problem solving for a number of diverse areas including design, manufacturing, Information Technology (IT), social communities of practice, and economics...
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Andrzej Czyżewski prof. dr hab. inż.
PeopleProf. zw. dr hab. inż. Andrzej Czyżewski jest absolwentem Wydziału Elektroniki PG (studia magisterskie ukończył w 1982 r.). Pracę doktorską na temat związany z dźwiękiem cyfrowym obronił z wyróżnieniem na Wydziale Elektroniki PG w roku 1987. W 1992 r. przedstawił rozprawę habilitacyjną pt.: „Cyfrowe operacje na sygnałach fonicznych”. Jego kolokwium habilitacyjne zostało przyjęte jednomyślnie w czerwcu 1992 r. w Akademii Górniczo-Hutniczej...
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Oxidative DNA damage: assessment of the role in carcinogenesis, atherosclerosis, and acquired immunodeficiency syndrome1 1This article is part of a series of reviews on “Oxidative DNA Damage and Repair.” The full list of papers may be found on the homepage of the journal.
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Seafloor relief reconstruction from side scan sonar data
PublicationSide scan sonar is one of the most widely used imaging systems in the underwater environment. It is relatively cheap and easy to deploy, in comparison with more powerful sensors. Although side scan sonar does not provide seafloor bathymetry directly, its records are directly related to seafloor images. In the paper, the method for 3D seafloor relief reconstruction from side scan sonar data is presented. The method is based on the...
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Paweł Możejko dr hab.
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Ion recognition properties of new pyridine-2,6-dicarboxamide bearing propeller-like pendant residues: multi-spectroscopic approach
PublicationThe synthesis and ion binding properties of new amide derived from propeller-like tris(2-pyridyl)amine and 2,6-pyridinedicarboxylic acid chloride were described. Amide binds divalent metal cations: copper(II), nickel(II), zinc(II), and lead(II) in acetonitrile. In acetonitrile:water mixture (9:1 v/v) amide interacts only with copper(II) and nickel(II) cations forming complexes of 1:1 stoichiometry. It was found that the introduction...
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Critical factors for the performance of chip array-based electrical detection of DNA for analysis of pathogenic bacteria
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Effects of flavonoids on expression of genes involved in cell cycle regulation and DNA replication in human fibroblasts
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DNA methylation analysis of benign and atypical meningiomas: correlation between RUNX3 methylation and WHO grade
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The Degree of Global DNA Hypomethylation in Peripheral Blood Correlates with That in Matched Tumor Tissues in Several Neoplasia
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Prolonged Quercetin Administration Diminishes the Etoposide-Induced DNA Damage in Bone Marrow Cells of Rats
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Bulky DNA adducts in human sperm: relationship with fertility, semen quality, smoking, and environmental factors
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Biomedical, Artificial Intelligence, and DNA Computing Photonics Applications and Web Engineering, Wilga, May 2012
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ppGpp-Dependent Negative Control of DNA Replication of Shiga Toxin-Converting Bacteriophages in Escherichia coli
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Establishing the background level of base oxidation in human lymphocyte DNA: results of an interlaboratory validation study
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Urinary Measurement of 8-OxodG, 8-OxoGua, and 5HMUra: A Noninvasive Assessment of Oxidative Damage to DNA
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Mass spectrometry reveals the presence of specific set of epigenetic DNA modifications in the Norway spruce genome
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Buserelin Acetate Reduces Mortality and DNA Defragmentation of Bovine Sperm Cells Exposed to Oxidative Stress
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Influence of addition of cobalamin to the extender on the post-thaw motility, viability, and DNA integrity of bovine ejaculate
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Serial depletion of Baltic herring since the Viking Age revealed by ancient DNA and population genomics
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On the Trail of the Oldest Domestic Cat in Poland. An Insight from Morphometry, Ancient DNA and Radiocarbon Dating
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