Search results for: Neurology
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JOURNAL OF CHILD NEUROLOGY
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Nature Reviews Neurology
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Open Neurology Journal
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Annals of Child Neurology
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Current Journal of Neurology
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BMJ Neurology Open
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Seminars in Pediatric Neurology
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JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
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Current Neurology and Neuroscience Reports
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Developmental Medicine and Child Neurology
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Current Treatment Options in Neurology
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Annals of Clinical and Translational Neurology
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Iranian Journal of Child Neurology
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CONTINUUM Lifelong Learning in Neurology
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Annals of Indian Academy of Neurology
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JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY
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JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
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Nature Clinical Practice Neurology
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NEUROLOGY PSYCHIATRY AND BRAIN RESEARCH
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Annals of Clinical and Experimental Neurology
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Advances in Psychiatry and Neurology
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Polish Journal of Neurology and Neurosurgery
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Egyptian Journal of Neurology Psychiatry and Neurosurgery
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Chinese Journal of Contemporary Neurology and Neurosurgery
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Swiss Archives of Neurology, Psychiatry and Psychotherapy
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Pharmacotherapy in Psychiatry and Neurology
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EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY
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LANCET NEUROLOGY
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Romanian Journal of Neurology/ Revista Romana de Neurologie
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CURRENT OPINION IN NEUROLOGY
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DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
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Pathological brain network activity: memory impairment in epilepsy
PublicationOur thinking, memory and cognition in general, relies upon precisely timed interactions among neurons forming brain networks that support cognitive processes. The surgical evaluation of drug-resistant epilepsy using intracranial electrodes provides a unique opportunity to record directly from human brain and to investigate the coordinated activity of cognitive networks. In this issue of Neurology®, Kleen and colleagues1 implicate...
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Gamma oscillations precede interictal epileptiform spikes in the seizure onset zone
PublicationOBJECTIVE: To investigate the generation, spectral characteristics, and potential clinical significance of brain activity preceding interictal epileptiform spike discharges (IEDs) recorded with intracranial EEG. METHODS: Seventeen adult patients with drug-resistant temporal lobe epilepsy were implanted with intracranial electrodes as part of their evaluation for epilepsy surgery. IEDs detected on clinical macro- and research microelectrodes...
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Newborn screening and gene therapy in SMA: Challenges related to vaccinations
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Respiratory Syndrome Coronavirus Infections: Possible Mechanisms of Neurological Implications—A Systematic Review
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Respiratory Syndrome Coronavirus Infections: Possible Mechanisms of Neurological Implications—A Systematic Review
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The Impact of Common Epidemiological Factors on Gray and White Matter Volumes in Magnetic Resonance Imaging–Is Prevention of Brain Degeneration Possible?
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10Kin1day: A Bottom-Up Neuroimaging Initiative
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Incident dementia and blood pressure lowering in the Hypertension in the Very Elderly Trial cognitive function assessment (HYVET-COG): a double-blind, placebo controlled trial
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Human Computer Interface for Tracking Eye Movements Improves Assessment and Diagnosis of Patients With Acquired Brain Injuries
PublicationOne of the first clinical signs differentiating the minimally conscious state from the vegetative state is the presence of smooth pursuit eye movements occurring in direct response to moving salient stimuli. Glasgow Coma Scale (GCS) is one of the most commonly used diagnostic tools for acute phase assessment of the level of consciousness, together with a neurological examination. These classic measures are limited to qualitative...
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Circulating miRNA profiles and the risk of hemorrhagic transformation after thrombolytic treatment of acute ischemic stroke: a pilot study
PublicationBackground: Hemorrhagic transformation (HT) in acute ischemic stroke is likely to occur in patients treated with intravenous thrombolysis (IVT) and may lead to neurological deterioration and symptomatic intracranial hemorrhage (sICH). Despite the complex inclusion and exclusion criteria for IVT and some useful tools to stratify HT risk, sICH still occurs in approximately 6% of patients because some of the risk factors for this...
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Direct electrical brain stimulation of human memory: lessons learnt and future perspectives
PublicationModulation of cognitive functions supporting human declarative memory is one of the grand challenges of neuroscience, and of vast importance for a variety of neuropsychiatric, neurodegenerative and neurodevelopmental diseases. Despite a recent surge of successful attempts at improving performance in a range of memory tasks, the optimal approaches and parameters for memory enhancement have yet to be determined. On a more fundamental...
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High frequency oscillations are associated with cognitive processing in human recognition memory
PublicationHigh frequency oscillations are associated with normal brain function, but also increasingly recognized as potential biomarkers of the epileptogenic brain. Their role in human cognition has been predominantly studied in classical gamma frequencies (30-100 Hz), which reflect neuronal network coordination involved in attention, learning and memory. Invasive brain recordings in animals and humans demonstrate that physiological oscillations...
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Human memory enhancement through electrical stimulation in the temporal cortex
PublicationDirect electrical stimulation of the human brain can elicit sensory and motor perceptions as well as recall of memories. Stimulating higher order association areas of the lateral temporal cortex in particular was reported to activate visual and auditory memory representations of past experiences (Penfield and Perot, 1963). We hypothesized that this effect could be used to modulate memory processing. Recent attempts at memory enhancement...
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Network oscillations modulate interictal epileptiform spike rate during human memory
PublicationEleven patients being evaluated with intracranial electroencephalography for medically resistant temporal lobe epilepsy participated in a visual recognition memory task. Interictal epileptiform spikes were manually marked and their rate of occurrence compared between baseline and three 2 s periods spanning a 6 s viewing period. During successful, but not unsuccessful, encoding of the images there was a significant reduction in...
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Interictal high-frequency oscillations in focal human epilepsy
PublicationPURPOSE OF REVIEW: Localization of focal epileptic brain is critical for successful epilepsy surgery and focal brain stimulation. Despite significant progress, roughly half of all patients undergoing focal surgical resection, and most patients receiving focal electrical stimulation, are not seizure free. There is intense interest in high-frequency oscillations (HFOs) recorded with intracranial electroencephalography as potential...
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Dissecting gamma frequency activities during human memory processing
PublicationGamma frequency activity (30-150 Hz) is induced in cognitive tasks and is thought to reflect underlying neural processes. Gamma frequency activity can be recorded directly from the human brain using intracranial electrodes implanted in patients undergoing treatment for drug-resistant epilepsy. Previous studies have independently explored narrowband oscillations in the local field potential and broadband power increases. It is not...
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High frequency oscillations in human memory and cognition: a neurophysiological substrate of engrams?
PublicationDespite advances in understanding the cellular and molecular processes underlying memory and cognition, and recent successful modulation of cognitive performance in brain disorders, the neurophysiological mechanisms remain underexplored. High frequency oscillations beyond the classic electroencephalogram spectrum have emerged as a potential neural correlate of fundamental cognitive processes. High frequency oscillations are detected...
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B35 The Significance The Level Of Mitochondrial Dna In Huntington's Disease
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B26 Differential mitochondrial DNA levels in HD patients depending on the cell type
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