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Search results for: ROZPOZNAWANIE DNA MORSKIEGO
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Global DNA methylation level in females with idiopathic scoliosis
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Oxidative stress in humans: validation of biomarkers of DNA damage
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Decisional DNA Based Conceptual Framework for Smart Manufacturing
PublicationThis paper presents the conceptual framework for systematic knowledge representation, storage and reuse of manufacturing information in a production scenario. This knowledge structure is designed for three levels in a manufacturing set up viz. first at the engineering objects level, second at process and finally at factory level. Virtual engineering object (VEO) deals with knowledge at the individual object/component/machine level...
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5-Bromo-2′-deoxycytidine—a potential DNA photosensitizer
PublicationA double-stranded oligonucleotide, 80 base pairs in length, was multiply labeled with 5-bromo-2′-deoxycytidine (BrdC) using polymerase chain reaction (PCR). The modified oligonucleotide was irradiated with 300 nm photons and its damage was assayed by employing DHPLC, LC-MS and denaturing polyacrylamide gel electrophoresis (PAGE). Two types of damage were demonstrated, namely, single strand breaks (SSBs) and intrastrand cross-links...
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Replicating DNA by cell factories: roles of central carbon metabolism and transcription in the control of DNA replication in microbes, and implications for understanding this process in human cells
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Viral infection-oxidative stress/DNA damage-aberrant DNA methylation: separate or interrelated events responsible for genetic instability and childhood ALL development?
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From DNA damage to G2 arrest: the many roles of topoisomerase II. W: Prog-ress in Cell Cycle Research. Ed. Meijer L., Jezequel A., Roberge M. London: Plenum Publ. Comp. Ltd**2003 vol. 5 chapt. 30 s. 295-300 Od uszkodzeń DNA do bloku w G2: wiele ról dla topoizomerazy II.
PublicationInhibitory DNA topoizomerazy II sa jednymi z najbardziej szeroko stosowanymi lekami przeciwnowotworowymi. Związki te indukuja pekniecia nici DNA i bloku progresji cyklu komorkowego w fazie G2. Jednak topoizomeraza II jest nie tylko celem molekularnym dla lekow przeciwnowtworowych ale enzym ten pelniwazna role w odpowiedzi komorkowej na dzialanie wielu lekow uszkadzajacych DNA. Topoizomeraza tworzy kompleksy molekularne z bialkami...
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Characterization of single-stranded DNA-binding proteins from the psychrophilic bacteria Desulfotalea psychrophila, Flavobacterium psychrophilum, Psychrobacter arcticus, Psychrobacter cryohalolentis, Psychromonas ingrahamii, Psychroflexus torquis, and Photobacterium profundum
PublicationBackground: Single-stranded DNA-binding proteins (SSBs) play essential roles in DNA replication, recombination and repair in Bacteria, Archaea and Eukarya. In recent years, there has been an increasing interest in SSBs, since they find numerous applications in diverse molecular biology and analytical methods. Results: We report the characterization of single-stranded DNA-binding proteins from the psychrophilic bacteria Desulfotalea...
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Exploring novel Cd(ii) complexes with 5-methyl-4-imidazolecarboxaldehyde: synthesis, structure, computational insights, and affinity to DNA through switchSense methodology
PublicationA series of four Cd(II) complexes with 5-methyl-4-imidazolecarboxaldehyde (L) with different inorganic anions within or outside the coordination sphere of general formula: [CdCl2 L2 ] (1), [CdBr2 L 2] (2), [CdI2L 2] (3), and [CdL4 ](PF6 )2 ·3H2 O (4) was synthesized through one-step and two-step reactions, respectively. All complexes were obtained as colorless crystals without the need for recrystallization and exhibited solubi- lity...
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Analysis of 5-Methylcytosine in DNA of Breast and Colon Cancer Tissues
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Global DNA demethylation as an epigenetic marker of human brain metastases
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Oxidative DNA Damage in Blood of CVD Patients Taking Detralex
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Gaussian Mixture Decomposition of Time-Course DNA Microarray Data
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Ancient DNA sequence quality is independent of fish bone weight
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Identification of Mitochondrial DNA (NUMTs) in the Nuclear Genome of Daphnia magna
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Spectroscopy and Dynamics of Cryptolepine in the Nanocavity of Cucurbit[7]uril and DNA
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Oxidatively Damaged DNA/Oxidative Stress in Children with Celiac Disease
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Effects of basal level of antioxidants on oxidative DNA damage in humans
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Syntheses and DNA binding of new cationic porphyrin–tetrapeptide conjugates
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Mitochondrial DNA levels in Huntington disease leukocytes and dermal fibroblasts
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Towards a software platform for experience administration: Decisional DNA Manager
PublicationW pracy przedstawiono koncepcje dochodzenia do konstrukcji platformy wspomagajacej procesy zarzadzania dosswiadczeniem decyzyjnym.
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Optimising DNA binding to carbon nanotubes by non-covalent methods
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Evaluating experimental molecular physics studies of radiation damage in DNA*
PublicationThe field of Atomic and Molecular Physics (AMP) is a mature field exploring the spectroscopy, excitation, ionisation of atoms and molecules in all three phases. Understanding of the spectroscopy and collisional dynamics of AMP has been fundamental to the development and application of quantum mechanics and is applied across a broad range of disparate disciplines including atmospheric sciences, astrochemistry, combustion and environmental...
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Evolutionary algorithm and decisional DNA for multiple travelling salesman problem
PublicationIn the real world, it is common to face optimization problems that have two or more objectives that must be optimized at the same time, that are typically explained in different units, and are in conflict with one another. This paper presents a hybrid structure that combines set of experience knowledge structures (SOEKS) and evolutionary algorithms, NSGA-II (Non-dominated Sorting Genetic Algorithm II), to solve multiple optimization...
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Intercalation of imidazoacridinones to DNA and its relevance to cytotoxicand antitumor activity
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Modelling charge transfer processes in C2+ -tetrahydrofuran collision for ion-induced radiation damage in DNA building blocks
PublicationInvestigations of collision-induced processes involving carbon ions and molecules of biological interest in particular DNA building blocks, are crucial to model the effect of radiation on cells in order to improve medical treatments for cancer therapy. Using carbon ions appears to be one of the most efficient ways to increase biological effectiveness to damage cancerous cells by irradiating deep-seated tumors. Therefore, interest...
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Effects of metallic silver island films on resonance energy transfer between N,N´-(dipropyl)-tetramethylindocarbocyanine (Cy3)- and N,N´-(dipro- pyl)-tetramethylindodicarbocyanine ( Cy5 )-labeled DNA.
PublicationZbadano nową metodę zwiększania odległości rezonansowego przekazywania energii poprzez umieszczanie znakowanych donorami i akceptorami oligomerów DNA pomiędzy dwoma płytkami pokrytymi nanocząsteczkami metalicznego srebra.
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Recognition of hazardous acoustic events employing parallel processing on a supercomputing cluster . Rozpoznawanie niebezpiecznych zdarzeń dźwiękowych z wykorzystaniem równoległego przetwarzania na klastrze superkomputerowym
PublicationA method for automatic recognition of hazardous acoustic events operating on a super computing cluster is introduced. The methods employed for detecting and classifying the acoustic events are outlined. The evaluation of the recognition engine is provided: both on the training set and using real-life signals. The algorithms yield sufficient performance in practical conditions to be employed in security surveillance systems. The...
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CERVIX UTERI, Exocervix - Female, 46 - Cell image [4140730008823071]
Open Research DataThis is the histopathological image of CERVIX UTERI cell sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Determination of tributylotin (TBT) in marine sediment using pressurised liquid extraction-gas chromatography-isotope dilution mass spectrometry (PLE-GC-IDMS) with a hexane-tropolone mixture
PublicationOpracowano metodę oznaczania zawartości tributylocyny w próbkach osadu morskiego. Na etapie izolacji zastosowano technikę przyspieszonej ekstrakcji za pomocą roztworu tropolonu w heksanie.Na etapie oznaczeń końcowych wykorzystano technikę chromatografii gazowej, stosując metodę spektrometrii mas rozcieńczenia izotopowego. Wyznaczono parametry walidacyjne opracowanej metody: granicę wykrywalności, precyzję, poprawność i niepewność.
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Granie nie tylko na murawie! Zostań Lewandowskim pipety i termocyklera. Synergia nowoczesnych metod analitycznych opartych o wykrywanie DNA z nowymi formami nauczania (grywalizacja).
PublicationKOnkurs Innowacji Dydaktyznych PG: "Granie nie tylko na murawie! Zostań Lewandowskim pipety i termocyklera. Synergia nowoczesnych metod analitycznych opartych o wykrywanie DNA z nowymi formami nauczania (grywalizacja)."
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Detection of Helicobacter rodentium-like DNA in the liver tissue of patients with chronic liver diseases by polymerase chain reaction–denaturing gradient gel electrophoresis and DNA sequence analysis
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Molecular dynamics simulations reveal the balance of forces governing the formation of a guanine tetrad—a common structural unit of G-quadruplex DNA
PublicationG-quadruplexes (G4) are nucleic acid conformations of guanine-rich sequences, in which guanines are arranged in the square-planar G-tetrads, stacked on one another. G4 motifs form in vivo and are implicated in regulation of such processes as gene expression and chromosome maintenance. The structure and stability of various G4 topologies were determined experimentally; however, the driving forces for their formation are not fully...
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Orzeczenie techniczne dotyczące stanu zachowania oraz możliwości dalszej eksploatacji uszkodzonych korozją słupów w przyziemiu budynku Akwarium Morskiego w Gdyni
PublicationOkreślenie możliwości nośnych oraz wskazanie sposobu naprawy uszkodzonych korozją słupów żelbetowych wykonanych w latach 30. ubigłego wieku.
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Obliczenia numeryczne konstrukcji dna jachtu podczas wejścia na mieliznę
PublicationPozytywne zmiany w dostępie do żeglarstwa, które dokonały się w ostatnim dziesięcioleciu spowodowały wzrost liczby osób uprawiających ten sport. Przepisy, wg których projektowane są jachty nie stawiają żadnych wymagań wytrzymałości konstrukcji na wypadek kolizji jednostki z dnem. Z doświadczenia wiadomo, że wejście jachtu na piaszczystą mieliznę nie musi powodować uszkodzeń, jednak kolizja z podwodną skałą w szkierach szwedzkich...
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Induced circularly polarized luminescence for revealing DNA binding with fluorescent dyes
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Regulation of the switch from early to late bacteriophage λ DNA replication
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Diagnosis of Brain Tumors Through Global Specific DNA Methylation Analysis
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Molecular Diagnostics of Brain Tumours by Measuring the 5-Methylcytosine Level in Their DNA
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P04.06 Temozolomide influence on global DNA methylation in glioblastoma cell lines
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Effects of Base π-Stacking on Damage to DNA by Low-Energy Electrons
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Mitochondrial DNA of Anisakis simplex S.S. as a Potential Tool for Differentiating Populations
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Novel Method of Identifying DNA Methylation Fingerprint of Acute Myeloid Leukaemia
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Direct cloning of heavy metal resistance genes from metagenomic DNA
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Central carbon metabolism influences fidelity of DNA replication in Escherichia coli
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Molecular differences in mitochondrial DNA genomes of dogs with malignant mammary tumours
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Analysis of differences in the stability of proteins encoded in mitochondrial DNA of model organisms
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High Concentrations of Excised Oxidative DNA Lesions in Human Cerebrospinal Fluid
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Severe oxidatively damaged DNA after cisplatin treatment of cancer patients
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Oxidative DNA damage in cancer patients: a cause or a consequence of the disease development?
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