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Search results for: PROSTATE GLAND
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Determination of amino acids in urine of patients with prostate cancer and benign prostate growth
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Fluoride and Pineal Gland
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Lipidomics as a Diagnostic Tool for Prostate Cancer
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Effects of an immunosuppressive treatment on the rat prostate
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Common variants of xeroderma pigmentosum genes and prostate cancer risk
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An inherited NBN mutation is associated with poor prognosis prostate cancer
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The presence of prostate cancer at biopsy is predicted by a number of genetic variants
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Clinical Relevance of Circulating Tumor Cells in Prostate Cancer Management
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Metastasis of the testicular germ cell tumors to the parotid gland
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A common nonsense mutation of the BLM gene and prostate cancer risk and survival
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Prognostic factors in postoperative radiotherapy for prostate cancer – tertiary center experience
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RAGE as a Novel Biomarker for Prostate Cancer: A Systematic Review and Meta-Analysis
PublicationThe receptor for advanced glycation end-products (RAGE) has been implicated in driving prostate cancer (PCa) growth, aggression, and metastasis through the fueling of chronic inflammation in the tumor microenvironment. This systematic review and meta-analysis summarizes and analyzes the current clinical and preclinical data to provide insight into the relationships among RAGE levels and PCa, cancer grade, and molecular effects....
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Do we need a new classification of parotid gland surgery?
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A personalised approach to prostate cancer screening based on genotyping of risk founder alleles
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Prepubic Minilaparotomy as the Surgical Approach in Treatment of Prostate Disorders in Dogs. A Cadaver Study
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Land of New Towns
PublicationReflexions on new towns throught the history.
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Preclinical [18F]tetrafluoroborate-PET/CT imaging of pituitary gland hyperplasia
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Robust HPLC–MS/MS method for levofloxacin and ciprofloxacin determination in human prostate tissue
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New approach in determination of urinary diagnostic markers for prostate cancer by MALDI-TOF/MS
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Drug-Eluting Biopsy Needle as a Novel Strategy for Antimicrobial Prophylaxis in Transrectal Prostate Biopsy
PublicationOBJECTIVES: To preclinically evaluate drug-eluting biopsy needles (patent pending WO2016118026) as a new potential way of antimicrobial prophylaxis for transrectal prostate biopsy. METHODS: Twenty steel biopsy needles have been coated with polyvinyl alcohol, ciprofloxacin, and amikacin. Modified biopsy needles have been randomly divided into 3 groups (1:2:1 ratio). Needles from group I were immersed for 30 minutes in dedicated...
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Monitoring Trends of Land Use and Land Cover Changes in Rajang River Basin
PublicationIn this study, the spatiotemporal changes in land use and land cover (LULC) were evaluated from 1992 to 2015 for the Rajang River Basin (RRB) located in the Sarawak State of Malaysia. The changes in water bodies cropped lands, and forests were assessed based on the available remotely sensed satellite data. Supervised classification with the Maximum-Likelihood-Algorithm technique was adopted for monitoring the LULC changes using...
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Grand Challenges on the Theory of Modeling and Simulation
PublicationModeling & Simulation (M&S) is used in many different fields and has made many significant contributions. As a field in its own right, there have been many advances in methodologies and technologies. In 2002 a workshop was held in Dagstuhl, Germany, to reflect on the grand challenges facing M&S. Ten years on, a series of M& S Grand Challenge activities are marking a decade of progress and are providing an opportunity to reflect...
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Problem of soil science based classification of land in the context of updating land and building records
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Regarding the “Tumour spillage of the pleomorphic adenoma of the parotid gland: A proposal for intraoperative measures”
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Regarding the concurrent presence of secretory carcinoma and Warthin’s tumor in the ipsilateral parotid gland
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New Perspectives for the Use of Potentilla alba Rhizomes to Treat Thyroid Gland Impairments
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Survivin expression in invasive pituitary gland adenomas with a diameter exceeding 20 mm
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The variant allele of the rs188140481 polymorphism confers a moderate increase in the risk of prostate cancer in Polish men
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Sulforaphane, a cruciferous vegetable-derived isothiocyanate, inhibits protein synthesis in human prostate cancer cells
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GC-MS-based untargeted metabolomics of plasma and urine to evaluate metabolic changes in prostate cancer
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The Prognostic Value of PI-RADS Score in CyberKnife Ultra-Hypofractionated Radiotherapy for Localized Prostate Cancer
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Anticancer Imidazoacridinone C-1311 is Effective in Androgen-Dependent and Androgen-Independent Prostate Cancer Cells
PublicationAndrogen receptor (AR) plays a crutial role in prostate cancer (PCa) development and metastasis. Here, we reported potent anti-PCa activity of a small molecule imidazoacridinone C-1311. In AR-positive PCa cells, C-1311 was found to inhibit the transcriptional activity of AR uncovering a novel mechanism that may be relevant for its anticancer effect. Mechanistically, C-1311 decreased AR binding to prostate-specific antigen (PSA)...
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Magnetic signatures of land vehicles
PublicationThe results of numerical simulations of the magnetic field surrounding of land vehicles' models have been presented in this paper. Vehicle containing of ferromagnetic elements distorts the Earth's magnetic field. This distortion can be measured by magnetometers. It is possible to detect and identify an object on the basis of its magnetic signature.
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Circulating Tumor Cells as a Marker of Disseminated Disease in Patients with Newly Diagnosed High-Risk Prostate Cancer
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PSMA-D4 Radioligand for Targeted Therapy of Prostate Cancer: Synthesis, Characteristics and Preliminary Assessment of Biological Properties
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The molecular function of kallikrein‐related peptidase 14 demonstrates a key modulatory role in advanced prostate cancer
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Preclinical toxicological examination of a putative prostate cancer-specific 4-methyl-1-nitroacridine derivative in rodents
PublicationW pracy przedstawiono wyniki przedklinicznych badań toksykologicznych zwiazków C-1748 i C-857 na szczurach Copenhagen i myszach BALB/c, po podaniu dootrzewnowym lub dożylnym. U myszy dawki letalne (LD50) dla C-1748 wynosiły odpowiednio 9 i 13,4 mg/kg w porównaniu z 2,2 i 3 mg/kg dla C-857. U szczurów po podaniu dootrzewnowym lub dożylnym dla C-1748 dawki LD50 wynosiły odpowiednio 4 i 1,3 mg/kg. Nie stwierdzono zmian w liczbie komórek...
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Exploring the Antitumor Efficacy of N-Heterocyclic Nitrilotriacetate Oxidovanadium(IV) Salts on Prostate and Breast Cancer Cells
PublicationThe crystal structures of two newly synthesized nitrilotriacetate oxidovanadium(IV) salts, namely [QH][VO(nta)(H2O)](H2O)2 (I) and [(acr)H][VO(nta)(H2O)](H2O)2 (II), were determined. Additionally, the cytotoxic effects of four N-heterocyclic nitrilotriacetate oxidovanadium(IV) salts— 1,10-phenanthrolinium, [(phen)H][VO(nta)(H2O)](H2O)0.5 (III), 2,2′-bipyridinium [(bpy)H][VO(nta)(H2O)](H2O) (IV), and two newly synthesized compounds...
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Partial-Body Irradiation in Patients with Prostate Cancer Treated with IMRT Has Little Effect on the Composition of Serum Proteome
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Electrochemistry from first-principles in the grand canonical ensemble
PublicationProgress in electrochemical technologies, such as automotive batteries, supercapacitors, and fuel cells, depends greatly on developing improved charged interfaces between electrodes and electrolytes. The rational development of such interfaces can benefit from the atomistic understanding of the materials involved by first-principles quantum mechanical simulations with Density Functional Theory (DFT). However, such simulations are...
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State Interventionism in Agricultural Land Turnover in Poland
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OC-0265: Whole body response to radiation in head and neck and prostate cancer patient; the serum proteome comparative analysis
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Pre-clinical evaluation of 1-nitroacridine derived chemotherapeutic agent that has preferential cytotoxic activity towards prostate cancer
PublicationPraca zawiera wyniki badań przedklinicznych pochodnej 1-nitroakrydyny C-1748 wobec komórek ludzkiego raka prostaty CaP in vitro, jak i przeszczepialnego na zwierzęta. W oparciu o fosforylację histonu H2AX jako markera podwójnych cięć DNA wykazano, że C-1748 jest bardziej aktywny w komórkach CaP niż HL60. Zidentyfikowano poza tym receptor androgenny (AR) jako cel molekularny badanego związku. W doświadczeniach na zwierzętach stwierdzono...
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Urine metabolic fingerprinting using LC–MS and GC–MS reveals metabolite changes in prostate cancer: A pilot study
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Foliate-Targeting Quantum Dots-β-Cyclodextrin Nanocarrier for Efficient Delivery of Unsymmetrical Bisacridines to Lung and Prostate Cancer Cells
PublicationTargeted drug delivery by nanocarriers molecules can increase the efficiency of cancer treatment. One of the targeting ligands is folic acid (FA), which has a high affinity for the folic acid receptors, which are overexpressed in many cancers. Herein, we describe the preparation of the nanoconjugates containing quantum dots (QDs) and β-cyclodextrin (β-CD) with foliate-targeting properties for the delivery of anticancer compound...
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Nicotinamide phosphoribosyltransferase expression in thyroid glands of patients with Graves' disease
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Tripped at the Finishing Line: The Åland Islands Internet Voting Project
PublicationThe Åland Islands spent years preparing an internet voting system, to be implemented for the first time in October 2019 for Parliamentary Elections. Despite this, the project was canceled the evening before the expected release date. In this paper, we explore the causes of this failure using a two-pronged approach including Information System failure perspectives and the approach to e-voting Mirabilis, focusing on organizational...
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BRCA1 Loss Preexisting in Small Subpopulations of Prostate Cancer Is Associated with Advanced Disease and Metastatic Spread to Lymph Nodes and Peripheral Blood
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Ultra-high performance liquid chromatographic determination of levofloxacin in human plasma and prostate tissue with use of experimental design optimization procedures
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The potential role of fatty acids in prostate cancer determined by GC–MS analysis of formalin-fixed paraffin-embedded tissue samples
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