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Search results for: THERAPEUTIC GARDEN
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Therapeutic biomaterials - application in neurology and cardiology
PublicationBiomaterials are of interest in most medical fields. It's hard to imagine life without them. And due to the ever-increasing demand, scientists are developing new materials. Diseases of the nervous and cardiovascular systems are still a big problem, which are associated with a limited ability to regenerate brain or heart tissues. Therefore, this review discusses the advancement in biomaterial engineering for the treatment of neurological...
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Therapeutic biomaterials – application in neurology and cardiology
PublicationBiomaterials are of interest in most medical fields. It's hard to imagine life without them. And due to the ever-increasing demand, scientists are developing new materials. Diseases of the nervous and cardiovascular systems are still a big problem, which are associated with a limited ability to regenerate brain or heart tissues. Therefore, this review discusses the advancement in biomaterial engineering for the treatment of neurological...
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CDK9: Therapeutic Perspective in HCC Therapy
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Therapeutic potential of adenosine analogues and conjugates
PublicationZaprezentowano przegląd literatury chemicznej na temat analogów i koniugatów adenozyny oraz ich potencjalne zastosowanie terapeutyczne. Zwrócono także uwagę na ich oddziaływanie z receptorami adenozyny.
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Zapotin, a Polymethoxyflavone, with Potential Therapeutic Attributes
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Therapeutic Potential of Multifunctional Tacrine Analogues
PublicationTacrine is a potent inhibitor of cholinesterases (acetylcholinesterase and butyrylcholinesterase) that shows limiting clinical application by liver toxicity. In spite of this, analogues of tacrine are considered as a model inhibitor of cholinesterases in the therapy of Alzheimer’s disease. The interest in these compounds is mainly related to a high variety of their structure and biological properties. In the present review, we...
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Phosphoroorganic Metal Complexes in Therapeutics
PublicationThe present mini-review highlights recent developments on antitumor activity of metal-based therapeutics which have been a subject of researches for the last few decades. In 1965, Rosenberg found that during an electrolysis on platinum electrodes a complex of Pt is generated which inhibited to a great extent a binary fission in Escherichia coli bacteria. This discovery started a new chapter in medicinal chemistry and the interesting...
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Therapeutic Potential of Multifunctional Derivatives of Cholinesterase Inhibitors
PublicationThe aim of this work is review of tacrine analogues from the last three years, which were not included in the latest review work, donepezil and galantamine hybrids from 2015 and rivastigmine derivatives from 2014. In this account we summarize the efforts toward the development and characterization of non-toxic inhibitors of cholinesterases based on mentioned drugs with various interesting additional properties such as antioxidant,...
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Urban design and therapeutic landscapes. Evolving theme.
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mTOR Signaling and Potential Therapeutic Targeting in Meningioma
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Antioxidants as a Potential Preventive and Therapeutic Strategy for Cadmium
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Photoinactivation of ESKAPE pathogens: overview of novel therapeutic strategy
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Therapeutic targeting of cathepsin C: from pathophysiology to treatment
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In vitro evaluation of novel lipopeptides with potential therapeutic application
PublicationThe synthesis of derivatives of Gly-His-Lys was elaborated followed by their antimicrobial activity investigation.
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Therapeutic Potential of Carnosine and Its Derivatives in the Treatment of Human Diseases
PublicationDespite significant progress in the pathogenesis, diagnosis, treatment, and prevention of cancer and neurodegenerative diseases, their occurrence and mortality are still high around theworld. The resistance of cancer cells to the drugs remains a significant problem in oncology today,while in the case of neuro-degenerative diseases, therapies reversing the process are still yet to be found. Furthermore, it is important to seek new...
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Delving into the Therapeutic Potential of Carica papaya Leaf against Thrombocytopenia
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Ginger (<i>Zingiber officinale</i>) – a spice with therapeutic properties
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Conjugate of Enkephalin and Temporin Peptides as a Novel Therapeutic Agent for Sepsis
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Neuroinflammation in Dementia—Therapeutic Directions in a COVID-19 Pandemic Setting
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Hypertension and coronary artery disease: Mechanistic insights and therapeutic challenges
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The effectiveness of therapeutic massage in neck pain – prospective, preliminary studies
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CRL4CRBN E3 Ligase Complex as a Therapeutic Target in Multiple Myeloma
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Quality monitoring of therapeutic processes in small treatment center for children
PublicationW artykule przedstawiono specyfikę oraz opis zasad nadzorowania procesów terapeutycznych w ramach systemu zarzadzania jakością w małej placówce służby zdrowia.
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Renal nerve ablation: Emerging role in therapeutics
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The Extracellular Bacterial HtrA Proteins as Potential Therapeutic Targets and Vaccine Candidates
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Revealing the epigenetic effect of temozolomide on glioblastoma cell lines in therapeutic conditions
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Poland: Quality Monitoring of Therapeutic Processes in a Small Treatment Center for Children
PublicationThis article presents the case of the first ISO 9001:2000-certified small healthcare organization (the Center for Therapy and Rehabilitation) providing therapeutic and rehabilitation services for disabled children in Northern Poland. Elements of the process-oriented healthcare quality system implementation, initial benefits, and the organization's quality system structure and process descriptions are described. Particular attention...
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New vitamin D analogs as potential therapeutics in melanoma
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SENSORY GARDENS INCLUSIVELY DESIGNED FOR VISUALLY IMPAIRED USERS.
PublicationThis paper discusses the design of sensory gardens, created especially to provide for the needs of sight impaired children and youth. These gardens should be inclusively available to general public. A sensory garden may have both therapeutic and educational effects. The research findings concerning therapeutic effects of contact with nature on children and youth are reviewed. The design problems related to providing a space for...
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Od garden city do ecocity
PublicationArtykuł omawia wybrane wątki ewolucji aspektów środowiskowych miasta w okresie od Garden City do czasów obecnych, omawiając narodziny, rozwój i ideę współczesnego miasta. Rozważania obejmują kolejno genezę i istotę miasta-ogrodu, jednostki sąsiedzkiej, modernizmu, postmodernizmu, nowego urbanizmu, oraz analizę współczesnych idei naprawy miast, zawartych w rozmaitych dokumentach, systemach certyfikacji, pozycjach literaturowych,...
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Myeloid-derived suppressor cells (MDSCs) in brain cancer: challenges and therapeutic strategies
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Therapeutic Qualities and Sustainable Approach to Heritage of the City. The Coastal Strip in Gdańsk, Poland
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Neuroprotective Effects of Cannabidiol in Hypoxic Ischemic Insult. The Therapeutic Window in Newborn Mice
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Isolation and Characterization of NP-POL Nonapeptide for Possible Therapeutic Use in Parkinson’s Disease
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Mapping Mechanostable Pulling Geometries of a Therapeutic Anticalin/CTLA-4 Protein Complex
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Purinergic implication in amyotrophic lateral sclerosis—from pathological mechanisms to therapeutic perspectives
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Novel therapeutic compound acridine–retrotuftsin action on biological forms of melanoma and neuroblastoma
PublicationPURPOSE: As a continuation of our search for anticancer agents, we have synthesized a new acridine-retrotuftsin analog HClx9-[Arg(NO2)-Pro-Lys-Thr-OCH3]-1-nitroacridine (named ART) and have evaluated its activity against melanoma and neuroblastoma lines. Both tumors develop from cells (melanocytes, neurons) of neuroectodermal origin, and both are tumors with high heterogeneity and unsatisfactory susceptibility to chemotherapies....
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Endothelial dysfunction due to eNOS uncoupling: molecular mechanisms as potential therapeutic targets
PublicationNitric oxide (NO) is one of the most important molecules released by endothelial cells, and its antiatherogenic properties support cardiovascular homeostasis. Diminished NO bioavailability is a common hallmark of endothelial dysfunction underlying the patho‑ genesis of the cardiovascular disease. Vascular NO is synthesized by endothelial nitric oxide synthase (eNOS) from the substrate L‑arginine (L‑Arg), with tetrahydrobiopterin...
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Nonsense-Mediated mRNA Decay: Pathologies and the Potential for Novel Therapeutics
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Blood pressure variability: Emerging role in risk assessment and therapeutics
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Role of Myeloid-derived suppressor cell (MDSC) in autoimmunity and its potential as a therapeutic target
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Current state of a dual behaviour of antimicrobial peptides-Therapeutic agents and promising delivery vectors
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CEACAM6 as a Novel Therapeutic Target to Boost HO-1—mediated Antioxidant Defense in COPD
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Targeting mTORs by omega-3 fatty acids: A possible novel therapeutic strategy for neurodegeneration?
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Research, theories and practical experience of therapeutic landscapes as a tool for urban open space design
PublicationThis paper reviews the research on therapeutic landscapes and discusses the design of urban parks and open green space. Firstly, the most relevant research on therapeutic landscapes is reviewed. Secondly, the practical experience of healing and therapeutic gardens is discussed. Finally, the conclusions leading to future use of therapeutic landscape concept in urban open space design are presented.
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Aptamer based tools for environmental and therapeutic monitoring: A review of developments, applications, future perspectives
PublicationNucleic acids in the form of aptamers play a growing and significant role in the targeted and rapid analysis of environmental sample composition and medical analyses. In this paper, the review of both aptamers synthesis methods as well as application of these short chain oligonucleotides (with critical comments on their strong and weak features) are given. The first ones include: systematic evolution of ligands by exponential enrichment...
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Positive results of serological tests for syphilis in pregnancy – diagnostic and therapeutic problems, report of two cases
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Angiotensin receptor - neprilysin inhibiton (ARNI) – A novel therapeutic concept for management of hypertension and heart failure
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Assessment of Therapeutic Progress After Acquired Brain Injury Employing Electroencephalography and Autoencoder Neural Networks
PublicationA method developed for parametrization of EEG signals gathered from participants with acquired brain injuries is shown. Signals were recorded during therapeutic session consisting of a series of computer assisted exercises. Data acquisition was performed in a neurorehabilitation center located in Poland. The presented method may be used for comparing the performance of subjects with acquired brain injuries (ABI) who are involved...
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Green Therapy w projektowaniu ośrodków medycznych Green Therapy in complex design of health centres
PublicationKoncepcja przestrzenna ogrodu terapeutycznego podporządkowana jest generalnej idei otwierania się projektantów na poszukiwanie nowych możliwości poprawy samopoczucia odbiorcy - poprzez zapewnienie użytkownikom poczucia bezpieczeństwa, komfortu i odprężenia, harmonii. Dotyczy to nie tylko grupy osób chorych, które dręczone są przez niepokoje i napięcia wywołane przez niepełnosprawność czy chorobę, ale także pacjentów w różnym wieku...