Filters
total: 3500
filtered: 1365
-
Catalog
- Publications 1365 available results
- Journals 186 available results
- Publishing Houses 4 available results
- People 485 available results
- Inventions 1 available results
- Projects 24 available results
- Research Teams 1 available results
- e-Learning Courses 167 available results
- Events 197 available results
- Open Research Data 1070 available results
Chosen catalog filters
displaying 1000 best results Help
Search results for: KANCERZ UCZELNI
-
Comparison of RP-HPLC columns used for determination of nucleoside metabolic patterns in urine of cancer patients
Publication -
A novel green one-step synthesis of gold nanoparticles using crocin and their anti-cancer activities
Publication -
Altered Expression of ESR1, ESR2, PELP1 and c-SRC Genes Is Associated with Ovarian Cancer Manifestation
Publication -
Serum levels of IL-6, IL-8 and CRP as prognostic factors in epithelial ovarian cancer
Publication -
Combinatory Treatment with miR-7-5p and Drug-Loaded Cubosomes Effectively Impairs Cancer Cells
Publication -
Global wealth disparities drive adherence to COVID-safe pathways in head and neck cancer surgery
Publication -
Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study
Publication -
Tuning of the Anti-Breast Cancer Activity of Betulinic Acid via Its Conversion to Ionic Liquids
Publication -
The analysis of human leukocyte antigen‐G level in patients with endometrial cancer by Western blot technique
Publication -
Preoperative nutritional support in cancer patients with no clinical signs of malnutrition—prospective randomized controlled trial
Publication -
Accuracy of Pretreatment Ultrasonography Assessment of Intra-Abdominal Spread in Epithelial Ovarian Cancer: A Prospective Study
PublicationThe aim of this study was to test the accuracy of ultrasonography performed by gynecological oncologists for the preoperative assessment of epithelial ovarian cancer (EOC) spread in the pelvis and abdominal cavity. A prospective, observational cohort study was performed at a single tertiary cancer care unit. Patients with suspected EOC were recruited and underwent comprehensive transvaginal and abdominal ultrasonography performed...
-
Natural Products Counteracting Cardiotoxicity during Cancer Chemotherapy: The Special Case of Doxorubicin, a Comprehensive Review
PublicationCardiotoxicity is a frequent undesirable phenomenon observed during oncological treatment that limits the therapeutic dose of antitumor drugs and thus may decrease the effec-‐‑ tiveness of cancer eradication. Almost all antitumor drugs exhibit toxic properties towards cardiac muscle. One of the underlying causes of cardiotoxicity is stimulation of oxidative...
-
pH-Responsive Drug Delivery Nanoplatforms as Smart Carriers of Unsymmetrical Bisacridines for Targeted Cancer Therapy
PublicationSelective therapy and controlled drug release at an intracellular level remain key challenges for effective cancer treatment. Here, we employed folic acid (FA) as a self-navigating molecule in nanoconjugates containing quantum dots (QDs) and β-cyclodextrin (β-CD) for the delivery of antitumor unsymmetrical bisacridine compound (C-2028) to lung and prostate cancers as well as normal cells. The bisacridine derivative can form the...
-
Anticancer Imidazoacridinone C-1311 is Effective in Androgen-Dependent and Androgen-Independent Prostate Cancer Cells
PublicationAndrogen receptor (AR) plays a crutial role in prostate cancer (PCa) development and metastasis. Here, we reported potent anti-PCa activity of a small molecule imidazoacridinone C-1311. In AR-positive PCa cells, C-1311 was found to inhibit the transcriptional activity of AR uncovering a novel mechanism that may be relevant for its anticancer effect. Mechanistically, C-1311 decreased AR binding to prostate-specific antigen (PSA)...
-
Role of size scale of ZnO nanoparticles and microparticles on toxicity toward bacteria and osteoblast cancer cells
PublicationThe specific role of size scale, surface capping, and aspect ratio of zinc oxide (ZnO) particles on toxicity toward prokaryotic and eukaryotic cells was investigated. ZnO nano and microparticles of controlled size and mor- phology were synthesized by wet chemical methods. Cytotoxicity toward mammalian cells was studied using a human osteoblast cancer cell line and antibacterial activity using Gram-negative bacteria (Escherichia...
-
imPlatelet classifier: image‐converted RNA biomarker profiles enable blood‐based cancer diagnostics
PublicationLiquid biopsies offer a minimally invasive sample collection, outperforming traditional biopsies employed for cancer evaluation. The widely used material is blood, which is the source of tumor-educated platelets. Here, we developed the imPlatelet classifier, which converts RNA-sequenced platelet data into images in which each pixel corresponds to the expression level of a certain gene. Biological knowledge from the Kyoto Encyclopedia...
-
Cytokine IL6, but not IL-1β, TNF-α and NF-κB is increased in paediatric cancer patients
PublicationCytokines are responsible for maintaining homeostasis as cell growth, differentiation, migration and apoptosis mediators. They play a pivotal role in immune responses to inflammatory reactions. In oncological diseases, the cross-talk between cells of the immunological system and cells of the tumour microenvironment is led by cytokines. Also, the overproduction of cytokines may change the tumour microenvironment and stimulate tumour...
-
Low prevalence of CDKN2A/ARF mutations among early-onset cancers of breast, pancreas and malignant melanoma in Poland
Publication -
Recent advances in 3D bioprinted tumor models for personalized medicine
PublicationCancerous tumors are among the most fatal diseases worldwide, claiming nearly 10 million lives in 2020. Due to their complex and dynamic nature, modeling tumors accurately is a challenging task. Current models suffer from inadequate translation between in vitro and in vivo results, primarily due to the isotropic nature of tumors and their microenvironment's relationship. To address these limitations, hydrogel-based 3D bioprinting...
-
Pomiar efektywności publicznych szkół wyższych za pomocą metod DEA, SFA oraz StoNED
PublicationW artykule oszacowano — za pomocą metod DEA, SFA i StoNED — efektywność działalności dydaktycznej i naukowej 58 publicznych szkół wyższych w 2014 r. (analiza porównawcza wyników). Wyniki działalności dydaktycznej mierzono przeliczeniową liczbą absolwentów, a działalności naukowej — liczbą nadanych stopni naukowych; w obu przypadkach za nakłady przyjęto liczbę pracowników naukowo-dydaktycznych, pozostałych pracowników niebędących...
-
Uniwersytet przyszłości organizacją fraktalną?
PublicationAutor proponuje wdrożenie idei organizacji fraktalnej do realiów uniwersytetu, w celu ograniczenia znaczenia barier kulturowych i organizacyjnych i przekształcenia uczelni w kierunku elastycznej organizacji. Takie cechy organizacji fraktalnej jak samoorganizacja, samopodobieństwo, witalność, dynamika i nawigowanie odniesiono do realiów współczenej uczelni wskazując ich znaczenie dla wsparcia rozwoju uczelni w społeczeństwie wiedzy....
-
Podejście adaptacyjne do problemu unikania kolizji na morzu
PublicationW referacie przedstawiono koncepcję podejścia adaptacyjnego do problemu unikania kolizji na morzu. Omawiany problem został zidentyfikowany jako należący do klasy problemów uczenia się ze wzmocnieniem. Zamieszczono opis podstawowych technik uczenia się ze wzmocnieniem, ich ograniczeń w omawianym zastosowaniu i sposobu w jaki można zapewnić efektywne uczenie się mimo wspomnianych ograniczeń. Zaprezentowana metoda została zilustrowana...
-
Technologie prośrodowiskowe dla budynków miejskich
PublicationWspółczesne duże miasta na całym świecie charakteryzują się dużą i wciąż rosnącą intensywnością zabudowy. Jest to tendencja utrwalona, którą pogłębia idea „miasta zwartego” jako rozwiązania dla problemu nadmiernego rozrastania terytorialnego i rozpraszania się struktury terenów miejskich. Jednocześnie realną potrzebą współczesnych miast jest poprawa jakości ich środowiska (eliminacja zanieczyszczeń, minimalizacja zjawiska miejskiej...
-
Rewitalizujaca rola sztuki w miejskiej przestrzni publicznej
PublicationWspółcześnie sztuka stała się narzędziem rewitalizującym miejskie przestrzenie publiczne. Obserwacja przemian jakie dokonują się w miastach dzięki jej obecności powoduje, że dostrzegany jest w niej nie tylko element estetyzujący, ale także naprawczy. Następuje wykorzystywanie działań twórczych do pobudzania aktywności lokalnych społeczności. Zauważalne włączanie mieszkańców do działań partycypacyjnych z udziałem sztuki powoduje,...
-
Role of miR-15b/16–2 cluster network in endometrial cancer: An in silico pathway and prognostic analysis
PublicationEndometrial cancer (EC) is the second most common cancer in women. A large number of human cancers exhibit dysregulation of microRNA expression including EC. MiR-15b/16–2 is one of the best-known miRNA clusters that is expressed in many types of cancer tissues. Herein, we analyzed the expression of individual miR-15b/16–2 cluster members, its paralogues, and their target network analysis, as well as their prognostic significance...
-
Intraoperative, Radio-Guided Sentinel Lymph Node Mapping in 110 Nonsmall Cell Lung Cancer Patients
Publication -
Blue-dye intraoperative sentinel lymph node mapping in early non-small cell lung cancer
Publication -
Prognostic relevance of demographics and surgical practice for patients with gastric cancer in two centers: in Poland versus Germany
Publication -
Clinical and Biological Significance of ESR1 Gene Alteration and Estrogen Receptors Isoforms Expression in Breast Cancer Patients
Publication -
Molecular profiles of thyroid cancer subtypes: Classification based on features of tissue revealed by mass spectrometry imaging
Publication -
Ionizing radiation affects the composition of the proteome of extracellular vesicles released by head-and-neck cancer cells in vitro
Publication -
Therapy-Related Changes in the Serum Proteome Patterns of Early Stage Breast Cancer Patients with Different Outcomes
Publication -
Potential clinical application of serum proteome mass spectrometry analyses in breast cancer patients diagnosis and management
Publication -
Analysis of Let-7 Family miRNA in Plasma as Potential Predictive Biomarkers of Diagnosis for Papillary Thyroid Cancer
Publication -
Preclinical toxicological examination of a putative prostate cancer-specific 4-methyl-1-nitroacridine derivative in rodents
PublicationW pracy przedstawiono wyniki przedklinicznych badań toksykologicznych zwiazków C-1748 i C-857 na szczurach Copenhagen i myszach BALB/c, po podaniu dootrzewnowym lub dożylnym. U myszy dawki letalne (LD50) dla C-1748 wynosiły odpowiednio 9 i 13,4 mg/kg w porównaniu z 2,2 i 3 mg/kg dla C-857. U szczurów po podaniu dootrzewnowym lub dożylnym dla C-1748 dawki LD50 wynosiły odpowiednio 4 i 1,3 mg/kg. Nie stwierdzono zmian w liczbie komórek...
-
Mass spectrometry-based serum proteome pattern analysis in molecular diagnostics of early stage breast cancer
Publication -
Polyamidoamine Dendrimers Decorated Multifunctional Polydopamine Nanoparticles for Targeted Chemo- and Photothermal Therapy of Liver Cancer Model
Publication -
Insights into the Effects of Cancer Associated Mutations at the UPF2 and ATP-Binding Sites of NMD Master Regulator: UPF1
Publication -
Spectrum of Epithelial-Mesenchymal Transition Phenotypes in Circulating Tumour Cells from Early Breast Cancer Patients
Publication -
DNA strand breaks induced by nuclear hijacking of neuronal NOS as an anti-cancer effect of 2-methoxyestradiol
Publication -
The Role of Matrix Gla Protein (MGP) Expression in Paclitaxel and Topotecan Resistant Ovarian Cancer Cell Lines
Publication -
Folic acid-conjugated mesoporous silica particles as nanocarriers of natural prodrugs for cancer targeting and antioxidant action
Publication -
Circulating Tumor Cells as a Marker of Disseminated Disease in Patients with Newly Diagnosed High-Risk Prostate Cancer
Publication -
Targeted Nano-Drug Delivery of Colchicine against Colon Cancer Cells by Means of Mesoporous Silica Nanoparticles
Publication -
New and Old Genes Associated with Primary and Established Responses to Paclitaxel Treatment in Ovarian Cancer Cell Lines
Publication -
The expression of Platelet-derived Growth factor receptors (PDGFRs) and their correlation with overall survival of patients with ovarian cancer
Publication -
Analysis of MDR genes expression and cross-resistance in eight drug resistant ovarian cancer cell lines
Publication -
Electrochemical generation of microbubbles by carbon nanotube interdigital electrodes to increase the permeability and material uptakes of cancer cells
Publication -
Interactions of Nitroaromatic Compounds with the Mammalian Selenoprotein Thioredoxin Reductase and the Relation to Induction of Apoptosis in Human Cancer Cells
Publication -
PUB073 Lung Cancer Screening with LDCT – Results of a Small Cohort Continual Monitoring (Pilot Silesian Study)
Publication