Filters
total: 2616
-
Catalog
- Publications 1629 available results
- Journals 416 available results
- Conferences 1 available results
- People 27 available results
- Projects 1 available results
- Laboratories 1 available results
- Research Teams 1 available results
- e-Learning Courses 13 available results
- Events 1 available results
- Open Research Data 526 available results
displaying 1000 best results Help
Search results for: metabolic surgery
-
Novel insights into conjugation of antitumor-active unsymmetrical bisacridine C-2028 with glutathione: characteristics of non-enzymatic and glutathione S-transferase-mediated reactions
PublicationUnsymmetrical bisacridines (UAs) are a novel potent class of antitumor-active therapeutics. A significant route of phase II drug metabolism is conjugation with glutathione (GSH), which can be non-enzymatic and/or catalyzed by GSH-dependent enzymes. The aim of this work was to investigate the GSH-mediated metabolic pathway of a representative UA, C 2028. GSH supplemented incubations of C-2028 with rat, but not with human, liver...
-
Synthesis, molecular structure, and metabolic stability of new series of N' -(2-alkylthio-4-chloro-5-methylbenzenesulfonyl)-1-(5-phenyl-1 H -pyrazol-1-yl)amidine as potential anti-cancer agents
PublicationA series of new N'-(2-alkylthio-4-chloro-5-methylbenzenesulfonyl)-1-(5-phenyl-1H-pyrazol-1-yl)amidine derivatives have been synthesized and evaluated in vitro by MTT assays for their antiproliferative activity against cell lines of colon cancer HCT-116, cervical cancer HeLa and breast cancer MCF-7. The studied compounds display selective activity mainly against HCT-116 and HeLa cells. Thus, five compounds show selective cytotoxic...
-
The Journal of Orthopaedics Trauma Surgery and Related Research
Journals -
Current Opinion in Otolaryngology & Head and Neck Surgery
Journals -
Chinese Journal of Bases and Clinics in General Surgery
Journals -
Oral and Maxillofacial Surgery Clinics of North America
Journals -
International Journal of Computer Assisted Radiology and Surgery
Journals -
Journal of Vascular Surgery-Venous and Lymphatic Disorders
Journals -
Facial Plastic Surgery Clinics of North America
Journals -
Indian Journal of Otolaryngology and Head & Neck Surgery
Journals -
GMS Interdisciplinary Plastic and Reconstructive Surgery DGPW
Journals -
Innovations-Technology and Techniques in Cardiothoracic and Vascular Surgery
Journals -
Journal of Vascular Surgery Cases and Innovative Techniques
Journals -
Journal of Hand Surgery-Asian-Pacific Volume
Journals -
JOURNAL OF HAND SURGERY-BRITISH AND EUROPEAN VOLUME
Journals -
Journal of Oral and Maxillofacial Surgery Medicine and Pathology
Journals -
World Journal for Pediatric and Congenital Heart Surgery
Journals -
Journal of the Egyptian Society of Cardio-Thoracic Surgery
Journals -
Operative Techniques in Otolaryngology - Head and Neck Surgery
Journals -
Korean Journal of Otorhinolaryngology-Head and Neck Surgery
Journals -
World Journal of Otorhinolaryngology - Head and Neck Surgery
Journals -
International Journal of Abdominal Wall and Hernia Surgery
Journals -
Journal of Feline Medicine and Surgery Open Reports
Journals -
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
Journals -
JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME
Journals -
Replicating DNA by cell factories: roles of central carbon metabolism and transcription in the control of DNA replication in microbes, and implications for understanding this process in human cells
Publication -
Dietary chicory root and chicory inulin trigger changes in energetic metabolism, stress prevention and cytoskeletal proteins in the liver of growing pigs – a proteomic study
Publication -
Amino acids metabolism and degradation is regulated during porcine oviductal epithelial cells (OECs) primary culture in vitro – a signaling pathways activation approach
Publication -
Flavin monooxygenases, FMO1 and FMO3, not cytochrome p450 isoenzymes, contribute to metabolism of anti-tumour triazoloacridinone, C-1305, in liver microsomes and HepG2 cells.
PublicationCelem pracy było określenie roli wybranych enzymów frakcji mikrosomalnej komórek wątroby w metabolizmie pochodnej triazoloakrydonu, związku C-1305. Wykazano, że badana pochodna ulega transformacji wobec frakcji enzymów izolowanych z hepatocytów szczurzych i ludzkich oraz jest metabolizowana przez komórki linii HepG2. Badania wykazały ponadto, że enzymami odpowiedzialnymi za obserwowane przemiany były monooksygenazy flawinowe, FMO1...
-
Multivariate Statistical Approach for Nephrines in Womenwith Obesity
PublicationCatecholamines are physiological regulators of carbohydrate and lipid metabolism during stress, but their chronic influence on metabolic changes in obese patients is still not clarified. The present study aimed to establish the associations between the catecholamine metabolites and metabolic syndrome (MS) components in obese women as well as to reveal the possible hidden subgroups of patients through hierarchical cluster analysis...
-
Microbiological Survey in Two Arctic Fjords: Total Bacterial Number and Biomass Comparison of Hornsund and Kongsfjorden
Publication -
Changes in Hydrographic Conditions Associated with 2005–2007 Storm Surges in the Odra Mouth — a Numerical Study
Publication -
Perspectives of Hospital Pharmacists Towards Biosimilar Medicines: A Survey of Polish Pharmacy Practice in General Hospitals
Publication -
Occurrence and variability of River Habitat Survey features across Europe and the consequences for data collection and evaluation
Publication -
Usage of Over-the-Counter and Herbal Products in Common Cold in Poland: Findings from Consumer Survey
Publication -
Microbiological Survey in Two Arctic Fjords: Total Bacterial Number and Biomass Comparison of Hornsund and Kongsfjorden
PublicationTwo microbiological parameters: total bacterial number (TBN) and biomass (BBM) were studied in two Arctic fjords: Hornsund and Kongsfjorden. Samples were collected from three sampling points in each fjord, from various water depth layers: from the surface to 75 m depth. Total bacterial number and biomass were examined using the DAPI staining and direct count method. The greater amount of bacteria, as well as highest bacterial biomass...
-
Microbiological Survey in Two Arctic Fjords: Total Bacterial Number and Biomass Comparison of Hornsund and Kongsfjorden
PublicationTwo microbiological parameters: total bacterial number (TBN) and biomass (BBM) were studied in two Arctic fjords: Hornsund and Kongsfjorden. Samples were collected from three sampling points in each fjord, from various water depth layers: from the surface to 75 m depth. Total bacterial number and biomass were examined using the DAPI staining and direct count method. The greater amount of bacteria, as well as highest bacterial biomass...
-
HYDROGRAPHIC SURVEY PLANNING FOR THE DETERMINATION OF TERRITORIAL SEA BASELINE ON THE EXAMPLE OF SELECTED POLISH SEA AREAS
Publication -
Current trends in consumption of multimedia content using online streaming platforms: A user-centric survey
PublicationIn its early days, consumption of multimedia content was only possible at a stationary terminal device. The music player was located at home, and had to have a physical drive. Over the last decade, there has been an enormous increase in the number of online streaming platforms. These services enable users to consume rich multimedia content on various devices. Thanks to the widespread and availability of portable devices, any person...
-
Daylight Appraisal Classes For Achitecture Students A Survey Combined With A Practical Assessment For Educational Training Recommendations
PublicationThe main objectives of this article are: (i) to present the relations between architecture students' subjective assessment of daylight in classrooms and the objective evaluation of daylit conditions using daylight simulations tools, (ii) to formulate guidelines and recommendations on daylight appraisal methods and tools which may be useful in architectural training. The methodology used includes an evaluation of the results of...
-
Data from the Survey on Entrepreneurs’ Opinions on Factors Determining the Employment of the Gdańsk University of Technology Graduates
PublicationThe dataset includes data from a survey on factors determining the employment of the Gdańsk University of Technology (Gdańsk Tech) graduates’ in the opinion of entrepreneurs. The survey was conducted in 2017. The research sample included 102 respondents representing various firms from the Pomeranian Voivodeship, Poland. The study concerned i.a. factors determining the decision to hire a candidate, methods of recruiting employees,...
-
Determinants of COVID-19 Impact on the Private Sector: A Multi-Country Analysis Based on Survey Data
PublicationOur paper aims to investigate the impact of COVID‐19 on private sector companies in terms of sales, production, finance and employment. We check whether the country and industry in which companies operate, government financial support and loan access matter to the behaviour and performances of companies during the pandemic. We use a microdata set from a worldwide survey of more than 15,729 companies conducted between April and...
-
A Web-GIS tool for diagnosing spatial orientation of young adults: design and evaluation of Geo-Survey
PublicationSpatial orientation is the effectiveness with which one is able to assess the mutual location of objects relative to a point of reference or a system of coordinates. Traditionally, this ability has been evaluated through field navigation tests, which do not take into account the prevailing influence of free online maps and virtual walks on a person’s interpretation of space. In this context, this study presents a Web-GIS tool designed...
-
Size-controlled synthesis of gold nanoparticles by a novel atmospheric pressure glow discharge system with a metallic pin electrode and a flowing liquid electrode
Publication -
Existence and uniqueness of monotone and bounded solutions for a finite-difference discretization a` la Mickens of the generalized Burgers–Huxley equation.
PublicationDeparting from a generalized Burgers–Huxley partial differential equation, we provide a Mickens-type, nonlinear, finite-difference discretization of this model. The continuous system is a nonlinear regime for which the existence of travelling-wave solutions has been established previously in the literature. We prove that the method proposed also preserves many of the relevant characteristics of these solutions, such as the positivity,...
-
Modulation of CYP3A4 activity and induction of apoptosis, necrosis and senescence by the antitumor imidazoacridinone C-1311 in human hepatoma cells
PublicationThere is increasing evidence that the expression level of drug metabolic enzymes affects the final cellular response following drug treatment. Moreover, anti-tumour agents may modulate enzymatic activity and/or cellular expression of metabolic enzymes in tumour cells. We investigated the influence of CYP3A4 overexpression on the cellular response induced by the anti-tumour agent C-1311 in hepatoma cells. C-1311-mediated CYP3A4...
-
Sergey Leble prof. dr hab.
People -
THORACIC AND CARDIOVASCULAR SURGEON
Journals -
Resting sympathetic outflow does not predict the morning blood pressure surge in hypertension
Publication -
OPERATION OF TWO-SHAFT GAS TURBINE IN THE RANGE OF OPEN ANTI-SURGE VALVE
PublicationThis paper presents experimental tests of full-scale two-shaft gas turbine in the range of open anti-surge valve (ASV). The tests were carried out in a laboratory gas- turbine test stand belonging to Department of Automation and Power Engineering , Faculty of Ocean Engineering and Ship Technology , Gdańsk University of Technology. The tests covered the start-up and low load operation of the turbine set in the range of open...