displaying 1000 best results Help
Search results for: METABOLIC DETOXIFICATION
-
On fatigue safety of metallic elements under static and dynamic loads.
PublicationGłównym celem monografii było wyznaczenie współczynników bezpieczeństwa i kryteriów projektowych z uwzględnieniem wpływu obciążeń statycznych oraz naprężeń średnich i resztowych na wytrzymałość zmęczeniową przy obciążeniach okresowych i/lub stochastycznych. Uzyskano to za pomocą wyznaczonych naprężeń równoważnych i równania Soderberga. Otrzymano kryteria w postaci zamkniętej i zgodnej z wzorem Milesa na trwałość zmęczeniową oraz...
-
The allergic and irritating reactions to metallic implants with trauma - orthopaedic patients
PublicationThe article presents the analysis of clinical operation complications after the treatment of long bones by mean of ostheosynthesis with the use of metal implants and endoprothesoplastic of hip joints.
-
Formation of Porous Structure of the Metallic Materials Used on Bone Implants
PublicationResearch on improvement of structure and fabrication methods of the bone implants are carried out for many years. Research are aimed to shape the structures, that will have a Young's modulus value similar to the value of the human bones Young's modulus. Depending on theporosity, Young's moduli can even be tailored to match the modulus of bone closer than solid metals can, thus reducing the problems associated with stress shielding...
-
Ductile fracture prediction in thin metallic plates subjected to explosions
PublicationPraca dotyczy modelowania zniszczenia ciągłego. Zaprezentowano wyniki eksperymentów przeprowadzonych na płytach metalowych poddanych eksplozjom oraz wyniki jednoosiowych prób laboratoryjnych. Opisano przyjęty model prawa konstytutywnego oraz kryteriów zniszczenia. Przedstawiono identyfikację parametrów materiałowych dla przyjętego modelu. Zaprezentowano model numeryczny oraz wyniki symulacji które następnie porównano z wynikami...
-
Comparison of experimental and numerical results on metallic plates subjected to explosions
PublicationA comparative study of dynamic response including damage and rupture processes of thin metallic plates subjected to shockwave impulses - explosions is presented. The results of the finite element numerical analysis are related to experiments. Due to high strain rate during explosions the elasto-viscoplastic Chaboches constitutive law including damage effects has been applied. For the assumed model proper material parameters identification...
-
Hybrid quantum-classical approach for atomistic simulation of metallic systems
PublicationThe learn-on-the-fly (LOTF) method [G. Csanyi et al., Phys. Rev. Lett. 93, 175503 (2004)] serves to seamlessly embed quantum-mechanical computations within a molecular-dynamics framework by continual local retuning of the potential's parameters so that it reproduces the quantum-mechanical forces. In its current formulation, it is suitable for systems where the interaction is short-ranged, such as covalently bonded semiconductors....
-
Bandwidth Dependence of the Propagation Channel in Circular Metallic BAN Environments
PublicationIn this paper, the bandwidth dependence of the propagation channel for Body Area Networks (BANs) in circular metallic environments is addressed and models are proposed to evaluate the appropriate short-term fading margins that should be considered as a function of the system bandwidth. The deployment of BANs in metallic indoor environments, such as ships, factories, warehouses and other similar environments, involves additional...
-
Disturbances of magnetic field in surrounding of mobile, metalic plate
PublicationThe uniform magnetic field of the Earth in the surrounding of a mobile, metalic object undergoes deformation by eddy currents. The influence of the moving conducting object on total magnetic field of the Earth depends on the object's shape, position and speed of the changes relative to the magnetic field's vector of the Earth as well as the electric conductivity and the relative magnetic permeability of the material. The disturbances...
-
The II phase metabolism of endogenous and exogenous compounds, including antitumor chemotherapeutics
PublicationThe II phase metabolism, it is a set of metabolism and excretion pathways of endogenous as well as exogenous compounds including xenobiotics. UDP-glucuronyltransferases (UGTs; EC 2.4.1.17) are the most crucial representatives of II phase enzymes, which are responsible for the transformation of bilirubine and bile acids, steroids and thyroid hormones and lipids. Exogenous compounds, including drugs, carcinogens, environmental pollutants...
-
The Impact of Different Drying Methods on the Metabolomic and Lipidomic Profiles of Arthrospira platensis
PublicationDrying is an inseparable part of industrial microalgae production. In this work, the impacts of eight different drying methods on the metabolome and lipidome of Arthrospira platensis were investigated. The studied drying methods were freeze drying (FD), sun drying (SD), air drying at 40 and 75 °C (AD′ and AD″), infrared drying at 40 and 75 °C (IRD′ and IRD″), and vacuum drying at 40 and 75 °C (VD′ and VD″). Results gathered by...
-
Renal Regulation of Calcium-Phosphate Metabolism in Single- and Twin Pregnant Goats
Publication -
Lactose and β-Glucosides Metabolism and Its Regulation in Lactococcus lactis: A Review
Publication -
Evaluation of bioconcentration and metabolism of diclofenac in mussels Mytilus trossulus - laboratory study
Publication -
Urinary metabolomic signature of muscle-invasive bladder cancer: A multiplatform approach
Publication -
Central carbon metabolism influences fidelity of DNA replication in Escherichia coli
Publication -
Vitamin D Metabolism Gene Polymorphisms and Their Associated Disorders: A Literature Review
Publication -
Activities of genes controlling sphingolipid metabolism in human fibroblasts treated with flavonoids
Publication -
Modulation of expression of genes involved in glycosaminoglycan metabolism and lysosome biogenesis by flavonoids
Publication -
Ascorbate and glutathione metabolism in embryo axes and cotyledons of germinating lupine seeds
Publication -
Completing Autophagy: Formation and Degradation of the Autophagic Body and Metabolite Salvage in Plants
Publication -
HORMONE AND METABOLIC RESEARCH
Journals -
DIABETES OBESITY & METABOLISM
Journals -
Journal of Endocrinology and Metabolism
Journals -
Nutritional Therapy & Metabolism
Journals -
Journal of Nutrition and Metabolism
Journals -
Archives of Endocrinology Metabolism
Journals -
Cardiovascular Endocrinology & Metabolism
Journals -
Diabetes & Metabolism Journal
Journals -
Drug Metabolism and Pharmacokinetics
Journals -
DIABETES NUTRITION & METABOLISM
Journals -
Journal of Diabetes & Metabolism
Journals -
Drug Metabolism Letters
Journals -
Human Nutrition and Metabolism
Journals -
MOLECULAR GENETICS AND METABOLISM
Journals -
METABOLISM-CLINICAL AND EXPERIMENTAL
Journals -
Obesity and Metabolism-Milan
Journals -
Endocrinology, Diabetes and Metabolism
Journals -
Journal of Bone Metabolism
Journals -
Metabolic Profiling of Jasminum grandiflorum L. Flowers and Protective Role against Cisplatin-Induced Nephrotoxicity: Network Pharmacology and In Vivo Validation
Publication -
NADPH-Cytochrome P-450 reductase in strongly involved in activating metabolic transformatios of 9-amino-1-nitroacridine antitumor agents
PublicationCelem pracy było wyjaśnienie roli reduktazy cytochromu P-450 jaką odgrywa ten enzym w przemianach metabolicznych dwóch związków przeciwnowotworowych z grupy pochodnych 1-nitroakrydyny. Zastosowano metodę HPLC do rozdziału metabolitów, a badania struktur przeprowadzono stosując metodę ESI-MS. Wykazano, że badana reduktaza jest zaangażowana bardziej w metabolizm aktywacyjny 1-nitroakrydyn niż metabolizm detoksykacyjny.
-
Hypericum alpestre extract exhibits in vitro and in vivo anticancer properties by regulating the cellular antioxidant system and metabolic pathway of L‐arginine
PublicationConventional treatment methods are not effective enough to fight the rapid increase in cancer cases. The interest is increasing in the investigation of herbal sources for the development of new anticancer therapeutics. This study aims to investigate the antitumor capacity of Hypericum alpestre (H. alpestre) extract in vitro and in vivo, either alone or in combination with the inhibitors of the L‐arginine/polyamine/nitric oxide...
-
Phase I and phase II metabolism simulation of antitumor-active 2-hydroxyacridinone with electrochemistry coupled on-line with mass spectrometry.
PublicationHere, we report the metabolic profile and the results of associated metabolic studies of 2-hydroxyacridinone (2-OH-AC), the reference compound for antitumor-active imidazo- and triazoloacridinones. Electrochemistry coupled with mass spectrometry was applied to simulate the general oxidative metabolism of 2-OH-AC for the first time. The reactivity of 2-OH-AC products to biomolecules was also examined. The usefulness of the electrochemistry...
-
Laser Surface Alloying of Aluminium Alloys with Cu/Fe Metallic Powders
Publication -
An Experimental Study on the Effect of Temperature on Acoustic Emission Characteristics in Metallic Structures
Publication -
Surface roughness of ceramic parts after lapping by abrasive-metallic tools
PublicationPrzedstawiono konstrukcję narzędzi ścierno-metalowych do obróbki na docierarce jednotarczowej. Wykonano badania docierania elementów z ceramiki tlenowej. Analizowano podstawowe parametry chropowatości powierzchni elementów z Al2O3 po obróbce narzędziami na bazie węglika boru.
-
Low-Profile Interdigitated UHF RFID Tag Antenna for Metallic Objects
PublicationThis article presents a novel miniature interdigitated ultra-high frequency (UHF) radio frequency identification (RFID) tag antenna that can be placed on metallic objects. The tag structure comprises two horizontal strip lines, each loaded with seven identical open stubs, and an integrated circuit (IC) chip connected directly to the feed lines in the middle of the structure. The perfect match to the IC chip’s impedance is realized...
-
X-Ray diffraction of the metallic nanostructures
Open Research DataMetallic nanostructures (gold and silver) were manufactured as a thermal annealing of gold or silver thin film. Gold films with thickness of 2.8 nm were deposited on a silicon substrates using a table-top dc magnetron sputtering coater (EM SCD 500, Leica), equipped with quartz microbalance for in-situ thickness measurements. Films were deposited from...
-
Cytochromes P-450: specyfic enzymes involved in metabolism of endogenous substances and xenobiotics
PublicationCytochromy P-450 to grupa enzymów hemoproteinowych występujących w prawie wszystkich organizmach żywych. Substratami tych enzymów są zarówno substancje endogenne jak i ksenobiotyki, włączając w to leki, dodatki do żywności oraz zanieczyszczenia środowiska. W pracy omówiono rolę polimorfizmu oraz indukcji P-450 w metabolizmie leków przeciwnowotworowych.
-
ClaR—a novel key regulator of cellobiose and lactose metabolism in Lactococcus lactis IL1403
Publication -
New supervised alignment method as a preprocessing tool for chromatographic data in metabolomic studies
Publication