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Search results for: reporter gene
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Response to Letter to the Editors regarding article entitled ‘Sex-related patient-reported brain fog symptoms in nonhospitalised COVID-19 patients’
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DNA Methylation Changes Induced by Redox-Active Compounds—Choosing the Right PCR-Based Method
PublicationThe impact of catechins on the expression profile of redox-related genes in HT29 cell line has been studied recently by our group using Oxidative Stress RT2 Profiler PCR Array. Within the examined panel of 84 genes, the down-regulation of SRXN1 gene was unique among other up-regulated genes. We hypothesized that the observed down-regulation resulted from DNA methylation and have exploited this observation to choose the proper strategy...
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Identification of Leaf Rust Resistance Genes in Selected Wheat Cultivars and Development of Multiplex PCR
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Expression profiles and genomic organisation of group A protein phosphatase 2C genes inBrassica oleracea
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Effects of traumatic life events, cognitive biases and variation in dopaminergic genes on psychosis proneness
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Association between Age at Diagnosis of Graves' Disease and Variants in Genes Involved in Immune Response
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Correction: Corrigendum: Modulation of expression of genes involved in glycosaminoglycan metabolism and lysosome biogenesis by flavonoids
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Correction: Corrigendum: Modulation of expression of genes involved in glycosaminoglycan metabolism and lysosome biogenesis by flavonoids
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Simultaneous siRNA-mediated silencing of pairs of genes coding for enzymes involved in glycosaminoglycan synthesis.
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A Study on Influence of Normalization Methods on Music Genre Classification Results Employing kNN Algorithms
PublicationThis paper presents a comparison of different normalization methods applied to the set of feature vectors of music pieces. Test results show the influence of min-nlax and Zero-Mean normalization methods, employing different distance functions (Euclidean, Manhattan, Chebyshev, Minkowski) as a pre-processing for genre classification, on k-Nearest Neighbor (kNN) algorithm classification results.
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Genre-Based Music Language Modeling with Latent Hierarchical Pitman-Yor Process Allocation
PublicationIn this work we present a new Bayesian topic model: latent hierarchical Pitman-Yor process allocation (LHPYA), which uses hierarchical Pitman-Yor pr ocess priors for both word and topic distributions, and generalizes a few of the existing topic models, including the latent Dirichlet allocation (LDA), the bi- gram topic model and the hierarchical Pitman-Yor topic model. Using such priors allows for integration of -grams with a topic model,...
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Genre-Based Music Language Modeling with Latent Hierarchical Pitman-Yor Process Allocation
PublicationIn this work we present a new Bayesian topic model: latent hierarchical Pitman-Yor process allocation (LHPYA), which uses hierarchical Pitman-Yor pr ocess priors for both word and topic distributions, and generalizes a few of the existing topic models, including the latent Dirichlet allocation (LDA), the bi- gram topic model and the hierarchical Pitman-Yor topic model. Using such priors allows for integration of -grams with a topic...
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Immunological response of sheep to injections of plasmids encoding Toxoplasma gondii SAG1 and ROP1 genes
PublicationInfection with the intracellular protozoan parasite Toxo¬plasma gondii (T. gondii) causes health problems to both humans and livestock and has a large economic impact worldwide. The immune response in sheep following infection with T. gondii was evaluated using six different combinations of plasmid DNA, recombinant antigen and adjuvant. Sheep were generally vaccinated twice by intramuscular injection with plasmid DNA containing...
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"Born Poland, Gone Global". The case of successful Polish ICT company - Aiton Caldwell
PublicationThis work examines the pathway to global markets of Polish ICT company Aiton Caldwell
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A&A Case Reports
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Anticancer Imidazoacridinone C-1311 is Effective in Androgen-Dependent and Androgen-Independent Prostate Cancer Cells
PublicationAndrogen receptor (AR) plays a crutial role in prostate cancer (PCa) development and metastasis. Here, we reported potent anti-PCa activity of a small molecule imidazoacridinone C-1311. In AR-positive PCa cells, C-1311 was found to inhibit the transcriptional activity of AR uncovering a novel mechanism that may be relevant for its anticancer effect. Mechanistically, C-1311 decreased AR binding to prostate-specific antigen (PSA)...
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Molecular differences in mitochondrial DNA (mtDNA) genomes of dogs with malignant mammary tumours
Open Research DataThe aim of this study was to determine molecular defects in mitochondrial DNA with the use of large-scale genome analysis in malignant canine mammary gland tumours and indicate whether these changes were linked with the carcinogenesis process. With the use of the NGS technology, we sequenced 27 samples of mtDNA isolated from blood and tumours obtained...
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Gene Therapy and Molecular Biology
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Methyl jasmonate as a control factor of the synthase squalene gene promoter and ginsenoside production in American ginseng hairy root cultured in shake flasks and a nutrient sprinkle bioreactor
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Impact of heat shock transcription factor 1 on global gene expression profiles in cells which induce either cytoprotective or pro-apoptotic response following hyperthermia
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Cation homeostasis and transport related gene markers are differentially expressed in porcine buccal pouch mucosal cells during long-term cells primary culture in vitro
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High pressure processing, acidic and osmotic stress increased resistance to aminoglycosides and tetracyclines and the frequency of gene transfer among strains from commercial starter and protective cultures
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Gene expression, DNA damage and other stress markers in Sinapis alba L. exposed to heavy metals with special reference to sewage sludge application on contaminated sites
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Integrating Statistical and Machine‐Learning Approach for Meta‐Analysis of Bisphenol A‐Exposure Datasets Reveals Effects on Mouse Gene Expression within Pathways of Apoptosis and Cell Survival
PublicationBisphenols are important environmental pollutants that are extensively studied due to different detrimental effects, while the molecular mechanisms behind these effects are less well understood. Like other environmental pollutants, bisphenols are being tested in various experimental models, creating large expression datasets found in open access storage. The meta‐analysis of such datasets is, however, very complicated for various...
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1 kapitola: Status report on frame sawing machines for narrow-kerf sawing
PublicationW opracowaniu przedstawiono genezę pilarek ramowych oraz przecinania drewna cienkimi piłami. Omówiono ekonomiczne i ekologiczne zalety tego typu obróbki. Zaprezentowano kinematykę współczesnych pilarek dostępnych na rynkach światowych: Orbit, Mamuth oraz DSG Sonic. Szczegółowo opisano układ napędowy pilarek DTPX-30 i PRW15 z hybrydowym napędem głównym i całkowitym wyrównoważeniem dynamicznym układu.