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Abstrakt
Hydrogels are three-dimensional polymer networks with hydrophilic properties. The modifiable properties of hydrogels and the structure resembling living tissue allow their versatile application. Therefore, increasing attention is focused on the use of hydrogels as bioinks for three-dimensional (3D) printing in tissue engineering. Bioprinting involves the fabrication of complex structures from several types of materials, cells, and bioactive compounds. Stem cells (SC), such as mesenchymal stromal cells (MSCs) are frequently employed in 3D constructs. SCs have desirable biological properties such as the ability to differentiate into various types of tissue and high proliferative capacity. Encapsulating SCs in 3D hydrogel constructs enhances their reparative abilities and improves the likelihood of reaching target tissues. In addition, created constructs can simulate the tissue environment and mimic biological signals. Importantly, the immunogenicity of scaffolds is minimized through the use of patient-specific cells and the biocompatibility and biodegradability of the employed biopolymers. Regenerative medicine is taking advantage of the aforementioned capabilities in regenerating various tissues muscle, bones, nerves, heart, skin, and cartilage.
Cytowania
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Autorzy (6)
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Milena Deptuła
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Małgorzata Zawrzykraj mgr
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Justyna Sawicka
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Michał Pikuła dr hab. med.
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Pełna treść
- Wersja publikacji
- Accepted albo Published Version
- DOI:
- Cyfrowy identyfikator dokumentu elektronicznego (otwiera się w nowej karcie) 10.1016/j.biopha.2023.115416
- Licencja
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Informacje szczegółowe
- Kategoria:
- Publikacja w czasopiśmie
- Typ:
- artykuły w czasopismach
- Opublikowano w:
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BIOMEDICINE & PHARMACOTHERAPY
nr 167,
ISSN: 0753-3322 - Język:
- angielski
- Rok wydania:
- 2023
- Opis bibliograficzny:
- Deptuła M., Zawrzykraj M., Sawicka J., Banach-Kopeć A., Tylingo R., Pikuła M.: Application of 3D- printed hydrogels in wound healing and regenerative medicine// BIOMEDICINE & PHARMACOTHERAPY -Vol. 167, (2023), s.115416-
- DOI:
- Cyfrowy identyfikator dokumentu elektronicznego (otwiera się w nowej karcie) 10.1016/j.biopha.2023.115416
- Źródła finansowania:
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- the National Science Centre [grant number 2020/04/X/ST5/01490], the Ministry of Science and Higher Education [Innovation Incubator 4.0, grant number 12/2020/II4.0], National Centre for Research and Development (grant number TECHMATSTRATEG2/410747/11/2019)
- Weryfikacja:
- Politechnika Gdańska
wyświetlono 113 razy
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