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Wyniki wyszukiwania dla: TARGETED CANCER THERAPY
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Extracellular miRNAs as Biomarkers of Head and Neck Cancer Progression and Metastasis
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C-reactive protein as a diagnostic and prognostic factor of endometrial cancer
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Notch signalling pathway as an oncogenic factor involved in cancer development
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The role of Snail1 transcription factor in colorectal cancer progression and metastasis
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The Role of miRNA-7 in the Biology of Cancer and Modulation of Drug Resistance
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Biological Effects of Cold Atmospheric Pressure Plasma on Skin Cancer
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Clinical Relevance of Circulating Tumor Cells in Prostate Cancer Management
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Analysis of 5-Methylcytosine in DNA of Breast and Colon Cancer Tissues
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Synthesis, molecular structure, and metabolic stability of new series of N' -(2-alkylthio-4-chloro-5-methylbenzenesulfonyl)-1-(5-phenyl-1 H -pyrazol-1-yl)amidine as potential anti-cancer agents
PublikacjaA series of new N'-(2-alkylthio-4-chloro-5-methylbenzenesulfonyl)-1-(5-phenyl-1H-pyrazol-1-yl)amidine derivatives have been synthesized and evaluated in vitro by MTT assays for their antiproliferative activity against cell lines of colon cancer HCT-116, cervical cancer HeLa and breast cancer MCF-7. The studied compounds display selective activity mainly against HCT-116 and HeLa cells. Thus, five compounds show selective cytotoxic...
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Enhanced Activity of P4503A4 and UGT1A10 Induced by Acridinone Derivatives C-1305 and C-1311 in MCF-7 and HCT116 Cancer Cells: Consequences for the Drugs’ Cytotoxicity, Metabolism and Cellular Response
PublikacjaActivity modulation of drug metabolism enzymes can change the biotransformation of chemotherapeutics and cellular responses induced by them. As a result, drug-drug interactions can be modified. Acridinone derivatives, represented here by C-1305 and C-1311, are potent anticancer drugs. Previous studies in non-cellular systems showed that they are mechanism-based inhibitors of cytochrome P4503A4 and undergo glucuronidation via UDP-glucuronosyltranspherase...
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Stage I non-small-cell lung cancer: long-term results of lobectomy versus sublobar resection from the Polish National Lung Cancer Registry†
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Extracellular matrix metalloproteinase inducer (EMMPRIN) expression correlates positively with active angiogenesis and negatively with basic fibroblast growth factor expression in epithelial ovarian cancer
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Primary mediastinal B-cell lymphoma – metabolic and anatomical features in 18FDG-PET/CT and response to therapy
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Factors affecting long-term efficacy of T regulatory cell-based therapy in type 1 diabetes
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Introductory investigations of dermatologic diode laser with wavelengths 975 nm: clinical therapy of Recklinghausen disease and of hemangiomas
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Influence of one‐night CPAP therapy on the changes of HIF‐1α protein in OSA patients: A pilot study
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Evaluation of the Combination of Muscle Energy Technique and Trigger Point Therapy in Asymptomatic Individuals with a Latent Trigger Point
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Phthalocyanine Derivatives Possessing 2-(Morpholin-4-yl)ethoxy Groups As Potential Agents for Photodynamic Therapy
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Dendrimeric Sulfanyl Porphyrazines: Synthesis, Physico-Chemical Characterization, and Biological Activity for Potential Applications in Photodynamic Therapy
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Evaluation of brain volume alterations in HCV-infected patients after interferon-free therapy: A pilot study
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Add-On Therapy with a Nighttime Dose of Doxazosin in Patients with Uncontrolled Hypertension: Effects on Autonomic Modulation of the Cardiovascular System
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Microbeam radiation therapy: Tissue dose penetration and BANG-gel dosimetry of thick-beams’ array interlacing
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The Value of Serum MicroRNA Expression Signature in Predicting Refractoriness to Bortezomib-Based Therapy in Multiple Myeloma Patients
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Oral antibiotic therapy improves fat absorption in cystic fibrosis patients with small intestine bacterial overgrowth
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Remdesivir-based therapy improved recovery of patients with COVID-19 in the SARSTer multicentre, real-world study
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Remdesivir-based therapy improved recovery of patients with COVID-19 in the SARSTer multicentre, real-world study
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Limitation of Futile Therapy in the Opinion of Nursing Staff Employed in Polish Hospitals—Results of a Cross-Sectional Study
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Physiological Biomarkers Assessed by Low‐Tech Exercise Tests Predict Complications and Overall Survival in Patients Undergoing Pneumonectomy Due to Lung Cancer
PublikacjaDue to its debilitating character pneumonectomy this is last‐resort procedure. Preoperative results of the 6‐min walking test (6MWT) help to identify high risk of postoperative complications and increased mortality in patients undergoing lobectomy for lung cancer. The aim of the study was to validate the value of 500 m in 6MWT as an indicator, which differentiates risk of complications in patients undergoing pneumonectomy. 125...
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Expression of Selected Epithelial-Mesenchymal Transition Transcription Factors in Endometrial Cancer
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25(OH)D3 in patients with ovarian cancer and its correlation with survival
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Serum Inhibin A and Inhibin B Levels in Epithelial Ovarian Cancer Patients
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Serum Anti-Müllerian Hormone Levels in Patients with Epithelial Ovarian Cancer
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Cadmium, arsenic, selenium and iron– Implications for tumor progression in breast cancer
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Metachronous adenocarcinoma in a gastric tube after radical surgery for oesophageal cancer
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A common nonsense mutation of the BLM gene and prostate cancer risk and survival
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Breast Cancer Heterogeneity Investigation: Multiple k-Means Clustering Approach
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Molecular Profiling for Predictors of Radiosensitivity in Patients with Breast or Head-and-Neck Cancer
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Erratum to: Sulforaphane inhibits growth of phenotypically different breast cancer cells
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Urinary metabolomic signature of muscle-invasive bladder cancer: A multiplatform approach
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Quality of life in long-term survivors of early stage endometrial cancer
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Diagnostic potential for a serum miRNA neural network for detection of ovarian cancer
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Prognostic factors in postoperative radiotherapy for prostate cancer – tertiary center experience
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Inhibition of protein glycosylation reverses the MDR phenotype of cancer cell lines
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Pharmacokinetics and pharmacodynamics of propofol in cancer patients undergoing major lung surgery
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Influence of Transurethral Resection of Bladder Cancer on Sexual Function, Anxiety, and Depression
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New data on antihypertensive drugs and risk of cancer: should we worry?
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Radiation-Induced Changes in Serum Lipidome of Head and Neck Cancer Patients
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Mixture model of NMR - its application to diagnosis and treatment of brain cancer
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Oxidative DNA damage in cancer patients: a cause or a consequence of the disease development?
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K-ras gene mutation as an early prognostic marker of colon cancer
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