Wyszukiwarka
wyświetlamy 1000 najlepszych wyników Pomoc
Wyniki wyszukiwania dla: TERGETING TUMOR CELLS
-
Chemopreventive activity of bioactive fungal fractions isolated from milk-supplemented cultures of Cerrena unicolor and Pycnoporus sanguineus on colon cancer cells
Publikacja -
Application of biocompatible and ultrastable superparamagnetic iron(iii) oxide nanoparticles doped with magnesium for efficient magnetic fluid hyperthermia in lung cancer cells
Publikacja -
Complete tumour regressions induced by vaccination with IL-12 gene-transduced tumour cells in combination with IL-15 in a melanoma model in mice
Publikacja -
Physicochemical properties of ternary oxovanadium(IV) complexes with oxydiacetate and 1,10-phenanthroline or 2,2′-bipyridine. Cytoprotective activity in hippocampal neuronal HT22 cells
Publikacja -
High Quality Independent From a Donor: Human Amniotic Fluid Derived Stem Cells—A Practical Analysis Based on 165 Clinical Cases
Publikacja -
Nlrp-3-Driven Interleukin 17 Production by γδT Cells Controls Infection Outcomes during Staphylococcus aureus Surgical Site Infection
Publikacja -
Bystander activation of Bordetella pertussis‐induced nasal tissue‐resident memory CD4 T cells confers heterologous immunity to Klebsiella pneumoniae
Publikacja -
The Effect of Physical Activity and Repeated Whole-Body Cryotherapy on the Expression of Modulators of the Inflammatory Response in Mononuclear Blood Cells among Young Men
Publikacja -
Synthesis, physical–chemical properties and in vitro photodynamic activity against oral cancer cells of novel porphyrazines possessing fluoroalkylthio and dietherthio substituents
Publikacja -
Replication of hepatitis C virus in peripheral blood mononuclear cells in patients with chronic hepatitis C treated with pegylated interferon alpha and ribavirin
Publikacja -
Safe-by-Design Ligand-Coated ZnO Nanocrystals Engineered by an Organometallic Approach: Unique Physicochemical Properties and Low Toxicity toward Lung Cells
Publikacja -
The changes of antioxidant defense system caused by quercetin administration do not lead to DNA damage and apoptosis in the spleen and bone marrow cells of rats
Publikacja -
Novel Lytic Enzyme of Prophage Origin from Clostridium botulinum E3 Strain Alaska E43 with Bactericidal Activity against Clostridial Cells
Publikacja -
Combination of ABT-737 and resveratrol enhances DNA damage and apoptosis in human T-cell acute lymphoblastic leukemia MOLT-4 cells
Publikacja -
The role of structural factors in the kinetics of cellular uptake of pyrazoloacridines and pyrazolopyrimidoakridines. Implications for overcoming multidrug resistance towards leukaemia K562/DOX cells.
PublikacjaOtrzymano dwie grupy związków: pyrazoloakrydony (PAC) i pyrazolopirymidoakrydony (PPAC). Zbadano molekularne podstawy różnic w aktywności cytotoksycznej otrzymanych związków na poziomie komórkowym wobec komórek opornych linii ludzkiej erytroleukemii K562/DOX z nadekspresją P-glikoproteiny. Zastosowano spektrofluorymetryczną metodę badania transportu związków, która pozwala obserwować zarówno dyfuzję fluoryzujących cząsteczek związku...
-
The induction of autophagy in human colon wt p53 and p53-null HCT116 cells by 4-methyl-1-nitroacridine derivative C-1748
PublikacjaPrzeprowadzone badania miały na celu określenie zdolności pochodnej 4-metylo-1-nitroakrydyny C-1748 do uruchomienia autofagii komórek ludzkiego raka okrężnicy HCT116 posiadających dziki gen p53 oraz podlinii nie posiadającej tego genu. Wszystkie eksperymenty przeprowadzone zostały przy stężeniu hamującym proliferację komórek nowotworowych w 90%. Wykazano, że indukowana przez C-1748 autofagia w komórkach raka okrężnicy jest zależna...
-
The increased level of cytochrome P450 isoenzyme CYP3A4 affects the cellular response in CHO cells upon antitumor imidazoacridinone C-1311 treatment
PublikacjaPochodna C-1311 to potencjalny związek przeciwnowotworowy, który dotarł do II fazy badań klinicznych. Związek ten ulega metabolicznej transformacji pod wpływem szczurzych i ludzkich białek mikrosomalnych. Wykazano, że białka cytochromu P450 odpowiadają za przemiany metaboliczne C-1311 jedynie w niewielkim stopniu. Z drugiej strony wykazano, że pochodna C-1311 jest inhibitorem białek cytochromu P450, zwłaszcza izoenzymu CYP1A2...
-
Modulation of mRNA and protein levels of CYP1A1, 1A2, and 1B1 in nontumorigenic breast epithelial cells (MCF10A) by cabbage juice and its active components
PublikacjaZbadano wpływ soków z kapusty oraz występujących w nich pochodnych indolowych i sulforafanu na poziom ekspresji enzymów odpowiedzialnych za metabolizm ksenobiotyków w tym estrogenów. Wykazano, że soki z kapusty i izolowane substancje mają podobny wpływ na poziom mRNA i białek enzymatycznych.
-
Triazoloacridone C-1305 abrogates the restriction checkpoint in cells lacking functional p53 and promotes their accumulation in the G2/M phase of the cell cycle
PublikacjaTriazoloakrydon C-1305, nowy inhibitor topoizomerazy II, wykazuje wysoką aktywość cytotoksyczną wobec komórek wielu typów nowotworów. Komórki mysie pozbawione genu PARP-1 wykazywały nadwrażliwość na działanie tego związku. W pracy testowaliśmy działanie związku wobec dwóch różnych komóek nowotworowych różniących się statusem p53: komórkami białaczki myelocytarnej HL-60 i raka sutka MCF-7. Wykazaliśmy, że inkubacja ze związkiem...
-
Electrochemical Charakterization of Prussian blue type nickel hexacyanoferrate redox mediator for potential application as charge relay in dye-sensitized solar cells
PublikacjaMateriał nieorganiczny o mieszanym przewodnictwie elektronowo jonowym jakim jest heksacyjanożelazian (II,III) niklu (II) (NiHCF) rozpatrywany był jako potencjalny przenośnik ładunku w ogniwach słonecznych sensybilizowanych pigmentem (DSSC). Stwierdzono, że reakcje redoksowe NiHCF są szybkie i odwracalne nie tylko w obecności elektrolitu wspomagającego ale również w stanie stałym. Użyteczność NiHCF zbadana została za pomocą tradycyjnego...
-
Iron doped manganese cobaltite spinel coatings produced by electrophoretic co-deposition on interconnects for solid oxide cells: Microstructural and electrical characterization
PublikacjaWe report a systematic microstructural and electrical characterization of iron doped Mn–Co spinel coatings processed by electrophoretic co-deposition of Mn1.5Co1.5O4 and Fe2O3 powders on Crofer 22 APU and AISI 441 steel substrates. Iron addition to Mn–Co spinel coating leads to a reduction of the area specific resistance on both substrates, after 3200 h at 750 °C. The Fe doped Mn–Co coating both leads to a thinner oxide scale and...
-
Adenomatoid tumor, NOS - Female, 39 - Tissue image [7050730000136981]
Dane BadawczeThis is the histopathological image of CORPUS UTERI tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Phyllodes tumor, borderline - Female, 40 - Tissue image [2270630026313381]
Dane BadawczeThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Phyllodes tumor, borderline - Female, 40 - Tissue image [2270630026316341]
Dane BadawczeThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Phyllodes tumor, borderline - Female, 40 - Tissue image [2270630026316201]
Dane BadawczeThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Phyllodes tumor, borderline - Female, 40 - Tissue image [2270630026317891]
Dane BadawczeThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Phyllodes tumor, borderline - Female, 40 - Tissue image [2270630026316641]
Dane BadawczeThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Phyllodes tumor, borderline - Female, 40 - Tissue image [2270630026319261]
Dane BadawczeThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Seromucinous borderline tumor - Female, 30 - Tissue image [927072956554101]
Dane BadawczeThis is the histopathological image of OVARY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
The mechanism of internalization study of QDgreen−CD−FA−C−2028 conjugate at IC80 value to cancer (H460, Du-145, and LNCaP) and normal (MRC-5 and PNT1A) cells
Dane BadawczeThe influence of different endocytosis inhibitors on the internalization of QDgreen−CD−FA−C−2028 conjugate at IC80 value in cancer (H460, Du-145, and LNCaP) and normal (MRC-5 and PNT1A) cells. First, the cells were preincubated with: drug-free medium (no inhibitor), at 4 °C, 5 µM Cytochalasin D, 30 µM Amiloride, 80 µM Dynasore, 25 µM Pitstop 2 and 1.5...
-
Cytotoxicity of C-2028, QDgreen-FA, QDred-FA, QDgreen-FA-C-2028 and QDred-FA-C-2028 aginst H460 cancer cells
Dane BadawczeThis study presents absorbance values of formazan product (converted from MTT) which corresponds the cytotoxicity of C-2028, QDgreen-FA, QDred-FA, QDgreen-FA-C-2028 and QDred-FA-C-2028 aginst H460 cancer cells. FA (folic acid) was used as a linker between quantum dots (QDs) and compound (C-2028) at different concentration (50-200 µM).
-
Seromucinous borderline tumor - Female, 30 - Tissue image [9270729565548331]
Dane BadawczeThis is the histopathological image of OVARY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Seromucinous borderline tumor - Female, 30 - Tissue image [9270729565543611]
Dane BadawczeThis is the histopathological image of OVARY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Mucinous borderline tumor - Female, 57 - Tissue image [11010630088564901]
Dane BadawczeThis is the histopathological image of OVARY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Mucinous borderline tumor - Female, 57 - Tissue image [11010630088568531]
Dane BadawczeThis is the histopathological image of OVARY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Mucinous borderline tumor - Female, 57 - Tissue image [11010630088563161]
Dane BadawczeThis is the histopathological image of OVARY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Mucinous borderline tumor - Female, 57 - Tissue image [11010630088561851]
Dane BadawczeThis is the histopathological image of OVARY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Mucinous borderline tumor - Female, 57 - Tissue image [1101063008856831]
Dane BadawczeThis is the histopathological image of OVARY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Mucinous borderline tumor - Female, 57 - Tissue image [11010630088569201]
Dane BadawczeThis is the histopathological image of OVARY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Mucinous borderline tumor - Female, 57 - Tissue image [11010630088563691]
Dane BadawczeThis is the histopathological image of OVARY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Mucinous borderline tumor - Female, 57 - Tissue image [11010630088565131]
Dane BadawczeThis is the histopathological image of OVARY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Mucinous borderline tumor - Female, 57 - Tissue image [11010630088569021]
Dane BadawczeThis is the histopathological image of OVARY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Seromucinous borderline tumor - Female, 30 - Tissue image [9270729565549021]
Dane BadawczeThis is the histopathological image of OVARY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Wilms tumor - Male, 11 - Tissue image [704024710495891]
Dane BadawczeThis is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
-
Wilms tumor - Male, 11 - Tissue image [5210730031821481]
Dane BadawczeThis is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
-
Wilms tumor - Male, 11 - Tissue image [5210730031824921]
Dane BadawczeThis is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
-
Wilms tumor - Male, 11 - Tissue image [5210730031826611]
Dane BadawczeThis is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
-
Wilms tumor - Male, 11 - Tissue image [5210730031824591]
Dane BadawczeThis is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
-
Wilms tumor - Male, 11 - Tissue image [5210730031825091]
Dane BadawczeThis is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
-
Wilms tumor - Male, 11 - Tissue image [7040347232569211]
Dane BadawczeThis is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.