Wyniki wyszukiwania dla: adipic acid

• CROSSLINKING OF EPOXY-OLIGOESTERIC MIXTURES IN THE PRESENCE OF DIOXYDIPHENYLPROPANE DIGLYCIDYL ETHER MODIFIED WITH ADIPIC ACID

  Publikacja

  • M. Bratychak
  • O. Zubal
  • B. Bashta
  • O. Ivashkiv
  • O. Shyshchak
  • J. Haponiuk
  • J. Haponiuk

  - Chemistry & Chemical Technology - Rok 2017

  Pełny tekst do pobrania w serwisie zewnętrznym

• The Oxolane Ring Opening of Some Muramic Acid Derivatives Under Acidic Conditions

  Publikacja

  • J. Samaszko-Fiertek
  • B. Dmochowska
  • R. Slusarz
  • J. Madaj
  • R. Ślusarz

  - LETTERS IN ORGANIC CHEMISTRY - Rok 2018

  Pełny tekst do pobrania w serwisie zewnętrznym

• How acidic amino acid residues facilitate DNA target site selection

  Publikacja

  • K. A. Hossain
  • M. Kogut
  • J. Słabońska
  • S. Sappati
  • M. Wieczór
  • J. Czub

  - PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA - Rok 2023

  Despite the negative charge of the DNA backbone, acidic residues (Asp/Glu) commonly participate in the base readout, with a strong preference for cytosine. In fact, in the solved DNA/protein structures, cytosine is recognized almost exclusively by Asp/Glu through a direct hydrogen bond, while at the same time, adenine, regardless of its amino group, shows no propensity for Asp/Glu. Here, we analyzed the contribution of Asp/Glu...

  Pełny tekst do pobrania w portalu

• AMINO ACIDS

  Czasopisma

  ISSN: 0939-4451 , eISSN: 1438-2199

• NUCLEIC ACIDS RESEARCH

  Czasopisma

  ISSN: 0305-1048 , eISSN: 1362-4962

• Nucleic Acid Therapeutics

  Czasopisma

  ISSN: 2159-3337 , eISSN: 2159-3345

• Arid Ecosystems

  Czasopisma

  ISSN: 2079-0961 , eISSN: 2079-0988

• Synthesis and biological activity of mycophenolic acid-amino acid derivatives

  Publikacja

  • D. Iwaszkiewicz-Grzes
  • G. Cholewinski
  • A. Kot-Wasik
  • P. Trzonkowski
  • K. Dzierzbicka

  - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - Rok 2013

  Pełny tekst do pobrania w serwisie zewnętrznym

• Immunosuppressive properties of amino acid and peptide derivatives of mycophenolic acid

  Publikacja

  • A. Siebert
  • G. Cholewiński
  • P. Trzonkowski
  • J. Rachoń

  - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - Rok 2020

  Mycophenolic acid (MPA) was coupled with amino acids and biologically active peptides including derivatives of tuftsin to modify its immunosuppressive properties. Both amino acid unit in the case of simple MPA amides and modifications within peptide moiety of MPA - tuftsin conjugates influenced the observed activity. Antiproliferative potential of the obtained conjugates was investigated in vitro and MPA amides with threonine methyl...

  Pełny tekst do pobrania w portalu

• Synthesis and biological activity of mycophenolic acid-amino acid derivatives

  Publikacja

  • D. Iwaszkiewicz-Grześ
  • G. Cholewiński
  • A. Kot-Wasik
  • P. Trzonkowski
  • K. Dzierzbicka

  - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - Rok 2013

  In search of new immunosuppressants, mycophenolic acid (MPA) was coupled with amino acid methyl esters followed by hydrolysis to analogs bearing free carboxylic groups. The obtained compunds were tested in vitro as growth inhibitors of lymphoid cell line (Jurkat) and human peripheral blood mononuclear cells (PBMC) from healthy donors. According to obtained results recovering of free carboxylic group increased their activity. Additionally,...

  Pełny tekst do pobrania w portalu