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Wyniki wyszukiwania dla: HUNTINGTON’S DISEASE
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Population pharmacokinetics of hydroxyurea for children and adolescents with sickle cell disease
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Definitions of health and disease among physicians and Społem PSS employees
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Oxidatively Damaged DNA/Oxidative Stress in Children with Celiac Disease
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Circulating suPAR as a biomarker of disease severity in children with proteinuric glomerulonephritis
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The effect of cigarette smoking on the clinical course of inflammatory bowel disease
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Vitamin D receptor gene polymorphisms in Alzheimer's disease patients
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Parkinson’s disease: Etiopathogenesis, molecular basis and potential treatment opportunities
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Demodicosis as an opportunistic infection in a patient with Crohn’s disease treated with infliximab
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The polypill: an emerging treatment alternative for secondary prevention of cardiovascular disease
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Hypertension and coronary artery disease: Mechanistic insights and therapeutic challenges
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Are advanced glycation end-products specific biomarkers for Alzheimer's disease?
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Nicotinamide phosphoribosyltransferase expression in thyroid glands of patients with Graves' disease
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The atherosclerotic heart disease and protecting properties of garlic: contemporary data
PublikacjaArtykuł jest pracą przeglądową zawierającą najnowsze dane dotyczące choroby serca w przebiegu miażdżycowym oraz ochonnych właściwości czosnku. Obecnie prowadzone badania wykazały fundamentalną rolę jaką odgrywa czosnek we wszystkich stadiach choroby. Liczne badania in-vitro potwierdzają zdolność czosnku do redukcji parametrów zachorowania na choroby serca w przebiegu miażdżycy: całkowity cholesterol, LDL, trigliceryny, utlenione...
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Thyroid Peroxidase as an Autoantigen in Hashimoto’s Disease: Structure, Function, and Antigenicity
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A New Technique of Spine Disease Treatment Supported by ADRSK1 Device
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Are rare diseases overlooked by medical education? Awareness of rare diseases among physicians in Poland: an explanatory study
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Combined Therapies for Lysosomal Storage Diseases
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Automatic assessment of the motor state of the Parkinson's disease patient --a case study
PublikacjaThis paper presents a novel methodology in which the Unified Parkinson's Disease Rating Scale (UPDRS) data processed with a rule-based decision algorithm is used to predict the state of the Parkinson's Disease patients. The research was carried out to investigate whether the advancement of the Parkinson's Disease can be automatically assessed. For this purpose, past and current UPDRS data from 47 subjects were examined. The results...
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Dynamic Modeling of COVID-19 Disease with Impact of Lockdown in Pakistan and Malaysia
PublikacjaBeing researchers, it is an utmost responsibility to provide insight on social issues thus, this work addresses the dynamic modeling of first and most contagious disease named as COVID-19 caused by coronavirus. The first case of COVID-19 appeared in Pakistan was on 26th February 2020 and in Malaysia on 27th February 2020; both patients had foreign travel history. In the paper, the number of total affected cases and total deaths...
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Multiplatform metabolomics provides insight into the molecular basis of chronic kidney disease
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THE COVID-19 DISEASE AND POLICY RESPONSE TO MITIGATE THE ECONOMIC IMPACT IN THE EU
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Increased plasma concentrations of interleukin 35 in patients with coronary artery disease
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Dual-task exercise as a therapy for executive motor function in Parkinson’s disease
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Oxidative DNA damage in cancer patients: a cause or a consequence of the disease development?
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Relationship between selected DNA polymorphisms and coronary artery disease complications
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Proteomic and lipidomic biomarkers in the diagnosis and progression of inflammatory bowel disease – a review
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A CNN based coronavirus disease prediction system for chest X-rays
PublikacjaCoronavirus disease (COVID-19) proliferated globally in early 2020, causing existential dread in the whole world. Radiography is crucial in the clinical staging and diagnosis of COVID-19 and offers high potential to improve healthcare plans for tackling the pandemic. However high variations in infection characteristics and low contrast between normal and infected regions pose great challenges in preparing radiological reports....
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A NUMERICAL STUDY ON THE DYNAMICS OF DENGUE DISEASE MODEL WITH FRACTIONAL PIECEWISE DERIVATIVE
PublikacjaThe aim of this paper is to study the dynamics of Dengue disease model using a novel piecewise derivative approach in the sense of singular and non-singular kernels. The singular kernel operator is in the sense of Caputo, whereas the non-singular kernel operator is the Atangana–Baleanu Caputo operator. The existence and uniqueness of a solution with piecewise derivative are examined for the aforementioned problem. The suggested...
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Glycyrrhetinic acid and its derivatives in infectious diseases
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System of breath collection and analysis for diseases detection
PublikacjaCollection and study of composition of the exhaled air is now intensively investigated to develop non-invasive medical diagnostics based on presence of metabolic compounds in the exhaled air. The process of collecting and processing of the exhaled air must fulfill relevant conditions to achieve satisfactory results. The paper presents the system of collecting samples of exhaled breath and the proposed methods of its analysis, using...
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Metal nanoparticles-assisted early diagnosis of diseases
PublikacjaEarly diagnosis is essential for the effective illness treatment, but traditional diagnostic approaches inevitably have major downsides. Recent advancements in nanoparticle-based biosensors have created new opportunities for accelerating diagnosis. High surface area, exceptional sensitivity, high specificity, and optical characteristics of metal and metal oxide nanoparticles have made it possible to detect a variety of health conditions...
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3D Hand Shape Modeling for Automatic Assessing Motor Performance in Parkinson's Disease
PublikacjaIn this paper a method for hand pattern processing to create a 3D hand model is presented. By applying a complete hand armature to the model obtained, an interpolation of three motor tests for an individual Parkinson's disease patient can be performed. To obtain the 3D hand model the top view of the hand from a web cam is analyzed. The hand contour is examined to find characteristic points that allows for dividing hand image into...
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Exhaled nitric oxide in smokers and former smokers with chronic obstructive pulmonary disease
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Chromoblastomycosis as an endemic disease in temperate Europe: first confirmed case and review of the literature
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Chlorpromazine-induced hyperprolactinemia in a young female and its relation with fibrocystic breast disease
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Molecular Mechanisms Associated with ROS-Dependent Angiogenesis in Lower Extremity Artery Disease
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Expert System as a classification method for optimal Legg-Calve-Perthes Disease treatment
PublikacjaZaproponowano utworzenie systemu eksperckiego jako metody klasyfikacji w prognozowaniu dowolnej formy leczenia dzieci z chorobą Legg-Calve-Perthesa. Obecnie nie ma jednego optymalnego sposobu leczenia choroby Perhtes'a i proponowana metoda jest próbą utworzenia wymiernego i uniwersalnego narzędzia, które będzie stanowiło podstawę przy podejmowaniu decyzji o najlepszym sposobie leczenia chorego stawu biodrowego. System ekspercki,...
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Isolation and Characterization of NP-POL Nonapeptide for Possible Therapeutic Use in Parkinson’s Disease
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Ambulatory pulse pressure and its contributors in autosomal dominant polycystic kidney disease
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The Relationship Between Gene Polymorphisms and Dipping Profile in Patients With Coronary Heart Disease
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Ultra-rare ultra-care: The unique burden of ultra rare disease caregiving
PublikacjaBackground: We sought to assesses the impact of caring for children with ultra rare diseases (URDs) on familycarers and to analyse the way these experiences differ among the caregivers of children diagnosed throughprenatal or newborn screening, and those with symptom-based diagnosis.Methods: A total of 200 caregivers of 219 URDs children completed an on-line survey regarding the challengesand experiences...
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Analysis of Serum of Patients With Alzheimer’s Disease for the Level of Advanced Glycation End Products
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Investigating the disease‐modifying properties of sclerotiorin in Alzheimer's therapy using acetylcholinesterase inhibition
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Deep Infiltrating Endometriosis in Adolescence: Early Diagnosis and Possible Prevention of Disease Progression
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SYNTHESIS OF PHOSPHORUS TACRINE ANALOGUES AS A NEW POTENTIAL ANTI-ALZHEIMER’S DISEASE AGENTS
PublikacjaA series of novel phosphorus tacrine derivatives was obtained in three steps, including synthesis of 9-chlorotacrine, connection of 9-chlorotacrine with hexamethylenediamine, 1,8-diaminooctane and 1,12-diaminododecane linkers and reaction of obtained tacrine diamine analogues with corresponding acid ester to give nine tacrine organophosphorus compounds. All of the obtained final structures were characterized by 1H NMR, 13C NMR,...
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Microbial diversity of inflamed and noninflamed gut biopsy tissues in inflammatory bowel disease.
PublikacjaBACKGROUND: Inflammatory bowel disease (IBD) is a chronic gastrointestinal condition without any known cause or cure. An imbalance in normal gut biota has been identified as an important factor in the inflammatory process. METHODS: Fifty-eight biopsies from Crohn's disease (CD, n = 10), ulcerative colitis (UC, n = 15), and healthy controls (n = 16) were taken from a population-based case-control study. Automated ribosomal intergenic...
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Investigating the disease- modifying properties of sclerotiorin in Alzheimer's therapy using acetylcholinesterase inhibition
PublikacjaAlzheimer's disease (AD) is a progressive neurodegenerative disorder caused due to the damage and loss of neurons in specific brain regions. It is the most common form of dementia observed in older people. The symptoms start with memory loss and gradually cause the inability to speak and do day-to-day activities. The cost of caring for those affected individuals is huge and is probably beyond most developing countries capability....
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Gender-Related Differences in Trimethylamine and Oxidative Blood Biomarkers in Cardiovascular Disease Patients
PublikacjaGender differences in the burden of cardiovascular disease (CVD) have been observed worldwide. In this study, plasmatic levels of trimethylamine (TMA) and blood oxidative biomarkers have been evaluated in 358 men (89 controls and 269 CVD patients) and 189 women (64 control and 125 CVD patients). The fluorescence technique was applied to determine erythrocyte membrane fluidity using 1,6-diphenyl-1,3,5-hexatriene (DPH) and Laurdan,...
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Development of a tropical disease diagnosis system using artificial neural network and GIS
PublikacjaExpert systems for diagnosis of tropical diseases have been developed and implemented for over a decade with varying degrees of success. While the recent introduction of artificial neural networks has helped to improve the diagnosis accuracy of such systems, this aspect is still negatively affected by the number of supported diseases. A large number of supported diseases usually corresponds to a high number of overlapping symptoms,...
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Role of omentin and vaspin in metabolic diseases in association with psoriasis
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