Wyniki wyszukiwania dla: PROTEASOME
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Potential allosteric modulators of the proteasome activity
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Proteome Science
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PEGylated substrates of NSP4 protease: A tool to study protease specificity
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Bladder cancer detection using a peptide substrate of the 20S proteasome
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JOURNAL OF PROTEOME RESEARCH
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Adrenal Secretory Protease
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A Peptidomimetic Fluorescent Probe to Detect the Trypsin β2 Subunit of the Human 20S Proteasome
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Novel internally quenched substrate of the trypsin-like subunit of 20S eukaryotic proteasome
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Inhibition of Human and Yeast 20S Proteasome by Analogues of Trypsin Inhibitor SFTI-1
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Future of Protease Activity Assays
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Non‐Proteasomal Urine Activity in Bladder Cancer
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Analysis of a Nuclear Intrinsically Disordered Proteome
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Applications of Unnatural Amino Acids in Protease Probes
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Design and synthesis of new substrates of HtrA2 protease
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Genetic and pharmacologic proteasome augmentation ameliorates Alzheimer’s-like pathology in mouse and fly APP overexpression models
PublikacjaThe proteasome has key roles in neuronal proteostasis, including the removal of misfolded and oxidized proteins, presynaptic protein turnover, and synaptic efficacy and plasticity. Proteasome dysfunction is a prominent feature of Alzheimer’s disease (AD). We show that prevention of proteasome dysfunction by genetic manipulation delays mortality, cell death, and cognitive deficits in fly and cell culture AD models. We developed...
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Genetic and pharmacologic proteasome augmentation ameliorates Alzheimer’s-like pathology in mouse and fly APP overexpression models
PublikacjaThe proteasome has key roles in neuronal proteostasis, including the removal of misfolded and oxidized proteins, presynaptic protein turnover, and synaptic efficacy and plasticity. Proteasome dysfunction is a prominent feature of Alzheimer’s disease (AD). We show that prevention of proteasome dysfunction by genetic manipulation delays mortality, cell death, and cognitive deficits in fly and cell culture AD models. We developed...
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Proteomic and bioinformatic analysis of a nuclear intrinsically disordered proteome
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Impact of imipramine on proteome of rat primary glial cells
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Substrate profiling of Zika virus NS2B‐NS3 protease
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Fecal Serine Protease Profiling in Inflammatory Bowel Diseases
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Structural and Functional Analysis of Human HtrA3 Protease and Its Subdomains
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Biochemical and Structural Characterization of SplD Protease from Staphylococcus aureus
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Temperature-induced changes of HtrA2(Omi) protease activity and structure
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Characteristic and specificity of protease activity of thermophilic bacteria Meiothermus ruber
PublikacjaThe primary purpose of research was to establish the possibility of using thermophilic bacteria Meiothermus ruber as a source of proteolytic enzymes. The main reason of searching new proteases is their commercial value especially in production of detergents, food, pharmaceuticals, leather, diagnostics or waste management. The development of this type processes will be possible by utilization of enzymes which have unique characteristics...
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An update on medium- and low-abundant blood plasma proteome of horse
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Interplay between Structure and Charge as a Key to Allosteric Modulation of Human 20S Proteasome by the Basic Fragment of HIV-1 Tat Protein
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Effect of chronic mild stress and imipramine on the proteome of the rat dentate gyrus
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Structural Determinants of Substrate Specificity of SplF Protease from Staphylococcus aureus
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Computational Selectivity Assessment of Protease Inhibitors against SARS-CoV-2
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Substrate specificity and inhibitory study of human airway trypsin-like protease
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Proteome changes upon in ovo stimulation with Lactobacillus synbiotic in chicken liver
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Lupine embryo axes under salinity stress. II. Mitochondrial proteome response
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Kallikrein 13 serves as a priming protease during infection by the human coronavirus HKU1
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Intra- and intersubunit changes accompanying thermal activation of the HtrA2(Omi) protease homotrimer
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Urinary Proteome of Newborn Calves—New Potential in Non-Invasive Neonatal Diagnostic
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Identification of serum proteome signatures of locally advanced and metastatic gastric cancer: a pilot study
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An Insight into the Proteome of Uveal Melanoma-Derived Ectosomes Reveals the Presence of Potentially Useful Biomarkers
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Changes in the Cell Wall Proteome of Leaves in Response to High Temperature Stress in Brachypodium distachyon
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The effects of p53 gene inactivation on mutant proteome expression in a human melanoma cell model
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An animal model of the procognitive properties of cysteine protease inhibitor and immunomodulatory peptides based on colostrum.
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The role of the LB structural loop and its interactions with the PDZ domain of the human HtrA3 protease
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The LA Loop as an Important Regulatory Element of the HtrA (DegP) Protease from Escherichia coli
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Modification of ileal proteome in growing pigs by dietary supplementation with inulin or dried chicory root
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Dietary Inclusion of Dried Chicory Root Affects Cecal Mucosa Proteome of Nursery Pigs
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Lactose-rich milk replacer modifies the proteome of bloodplasma in 2-week-old calves
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Organic solvents aggregating and shaping structural folding of protein, a case study of the protease enzyme
PublikacjaLow solubility of reactants or products in aqueous solutions can result in the enzymatic catalytic reactions that can occur in non-aqueous solutions. In current study we investigated aqueous solutions containing different organic solvents / deep eutectic solvents (DESs) that can influence the protease enzyme's activity, structural, and thermal stabilities. Retroviral aspartic protease enzyme is responsible for the cleavage of the...
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EP-1817: Radiotherapy-related changes in serum proteome patterns of head and neck cancer patients
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Virtual screening for small molecular non-covalent binders of the SARS-CoV-2 main protease
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Stress-related expression of the chloroplast EGY3 pseudoprotease and its possible impact on chloroplasts’ proteome composition
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Proteome Analysis of PC12 Cells Reveals Alterations in Translation Regulation and Actin Signaling Induced by Clozapine
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