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Maternal immune activation leads to age-related behavioral and immunological changes in male rat offspring - the effect of antipsychotic drugs
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Impact of active intra-complex rest intervals on post-back squat versus hip thrust jumping potentiation
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Catalase activity in blood fractions of patients with sporadic ALS
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Detrimental effects of chemotherapeutics and other drugs on the endothelium: A call for endothelial toxicity profiling
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Label-free testing strategy to evaluate packed red blood cell quality before transfusion to leukemia patients
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Possible contribution of IGF-1 to depressive disorder
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Galerkin finite element analysis of Darcy–Brinkman–Forchheimer natural convective flow in conical annular enclosure with discrete heat sources
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MHD darcy-forchheimer nanofluid flow and entropy optimization in an odd-shaped enclosure filled with a (MWCNT-Fe3O4/water) using galerkin finite element analysis
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Oxidative stress as a hidden cost of attractiveness in postmenopausal women
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Layered MoS2: effective and environment-friendly nanomaterial for photocatalytic degradation of methylene blue
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Risk of cadmium, lead and zinc exposure from consumption of vegetables produced in areas with mining and smelting past
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Metachronous adenocarcinoma in a gastric tube after radical surgery for oesophageal cancer
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Heart laceration during oesophagectomy for the treatment of oesophageal carcinoma
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Molecular Characterization of Growth Hormone-producing Tumors in the GC Rat Model of Acromegaly
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Trends and variability of the atmosphere–ocean turbulent heat flux in the extratropical Southern Hemisphere
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Hypsometric changes in urban areas resulting from multiple years of mining activity
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Chronic treatment with zinc hydroaspartate induces anti-inflammatory and anti-ulcerogenic activity in rats
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Isothiocyanates as effective agents against enterohemorrhagic Escherichia coli: insight to the mode of action
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Various modes of action of dietary phytochemicals, sulforaphane and phenethyl isothiocyanate, on pathogenic bacteria
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The effect of interleukin-35 on the integrity, ICAM-1 expression and apoptosis of human aortic smooth muscle cells
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Comparison of the effects of rosuvastatin monotherapy and atorvastatin-ezetimibe combined therapy on the structure of erythrocyte membranes in patients with coronary artery disease
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Application of Rotating Magnetic Fields Increase the Activity of Antimicrobials Against Wound Biofilm Pathogens
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Effect of intensive lipid-lowering therapies on cholinesterase activity in patients with coronary artery disease
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Potential of Biocellulose Carrier Impregnated with Essential Oils to Fight Against Biofilms Formed on Hydroxyapatite
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Nonsteroidal anti-inflammatory drugs modulate cellular glycosaminoglycan synthesis by affecting EGFR and PI3K signaling pathways
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Facile and cost-effective technique to control europium oxidation states in glassy fluorophosphate matrices with tunable photoluminescence
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Impact of isoflavone genistein on psoriasis in in vivo and in vitro investigations
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Correction: Corrigendum: Modulation of expression of genes involved in glycosaminoglycan metabolism and lysosome biogenesis by flavonoids
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Correction: Corrigendum: Modulation of expression of genes involved in glycosaminoglycan metabolism and lysosome biogenesis by flavonoids
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Modulation of expression of genes involved in glycosaminoglycan metabolism and lysosome biogenesis by flavonoids
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Polyoxygenated cyathane diterpenoids from the mushroom Cyathus africanus, and their neurotrophic and anti-neuroinflammatory activities
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New conjugates of muramyl dipeptide and nor-muramyl dipeptide linked to tuftsin and retro-tuftsin derivatives significantly influence their biological activity
PublikacjaOpisano syntezę nowych koniugatów MDP i nor-MDP z pochodnymi tuftsyny i retro-tuftsyny zawierającymi wiązanie izopeptydowe pomiędzy epsilon-aminową grupą lizyny, a karboksylową grupą Ala, Gly czy Val. Zbadano ich aktywność biologiczną, m.in. profil cytokinowy.
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Natural and synthetic acridines/acridones as antitumor agents: their biological activities and methods of synthesis.
PublikacjaPraca stanowi przegląd opisanych w literaturze chemicznej modyfikacji struktur naturalnych i syntetycznych pochodnych akrydyny i akrydonu. Artykuł obejmuje swym zakresem metody syntezy, a także wpływ budowy cząsteczek tych związków na ich aktywność przeciwnowotworową oraz mechanizm działania.
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T cell Activation Is Driven by an ADP-Dependent Glukosinase Linking Enhanced Glycolysis with Mitochondrial Reactive Oxygen Species Generation
PublikacjaMitochondria-originating reactive oxygen species control T cell receptor (TCR)-induced gene expression. Here, we show that TCR-triggered activation of ADP-dependent glucokinase (ADPGK), an alternative, glycolytic enzyme typical for Archaea, mediates generation of the oxidative signal. We also show that ADPGK is localized in the endoplasmic reticulum and suggest that its active site protrudes toward the cytosol. The ADPGK-driven...
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Therapeutic potential of adenosine analogues and conjugates
PublikacjaZaprezentowano przegląd literatury chemicznej na temat analogów i koniugatów adenozyny oraz ich potencjalne zastosowanie terapeutyczne. Zwrócono także uwagę na ich oddziaływanie z receptorami adenozyny.
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Carbon Nanohorns as Reaction Nanochambers – a Systematic Monte Carlo Study
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Thermal and optical properties of PMMA films reinforced with Nb2O5 nanoparticles
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Phase behavior of π-conjugated polymer and non-fullerene acceptor (PTB7-Th:ITIC) solutions and blends
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Systematic review of the effect of D‑mannose with or without other drugs in the treatment of symptoms of urinary tract infections/cystitis (Review)
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Periodontitis, female fertility and conception (Review)
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Arsenic causing gallbladder cancer disease in Bihar
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Global DNA demethylation as an epigenetic marker of human brain metastases
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Distinct characteristics of multisystem inflammatory syndrome in children in Poland
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COVID-19 infections in infants
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Psychosocial stress and cortisol stress reactivity predict breast milk composition
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Antitumor potential of new low molecular weight antioxidative preparations from the white rot fungus Cerrena unicolor against human colon cancer cells
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Investigations of changes in the arabinogalactan proteins (AGPs) structure, size and composition during the fruit ripening process
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Surfactant replacement therapy as promising treatment for COVID-19: an updated narrative review
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Temozolomide and sorafenib as programmed cell death inducers of human glioma cells
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Influence of proton irradiation on the magnetic properties of two-dimensional Ni(II) molecular magnet
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