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Search results for: LIVER TUMOUR SEGMENTATION
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Modulation of carcinogen metabolizing cytochromes p450 in rat liver and kidney by cabbage and sauerkraut juices: comparison with the effects of indole-3-carbinol and phenethyl isothiocyanate
PublicationThis study investigated the effect of raw cabbage and sauerkraut juices on the activity and expression of CYP1A1, 1A2, 1B1 and 2B in Wistar rat liver and kidney. The results were compared with those of two commercially available products of glucosinolates degradation: indole-3-carbinol (I3C) and phenethyl isothiocyanate (PEITC). Significant differences in the effect of the cabbage juices as well as I3C and PEITC between the liver...
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Fast multi-objective design optimization of microwave and antenna structures using data-driven surrogates and domain segmentation
PublicationPurpose Strategies and algorithms for expedited design optimization of microwave and antenna structures in multi-objective setup are investigated. Design/methodology/approach Formulation of the multi-objective design problem oriented towards execution of the population-based metaheuristic algorithm within the segmented search space is investigated. Described algorithmic framework exploit variable fidelity modeling, physics- and...
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Detection and segmentation of moving vehicles and trains using Gaussian mixtures, shadow detection and morphological processing
PublicationSolution presented in this paper combines background modelling, shadow detection and morphological and temporal processing into one system responsible for detection and segmentation of moving objects recorded with a static camera. Vehicles and trains are detected based on their pixellevel difference from the continually updated background model utilizing a Gaussian mixture calculated separately for every pixel. The shadow detection...
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Electrochemical and in silico approaches for liver metabolic oxidation of antitumor-active triazoloacridinone C -1305
Publication5-Dimethylaminopropylamino-8-hydroxytriazoloacridinone (C-1305) is a promising antitumor compound developed in our laboratory. A better understanding of its metabolic transformations is still needed to explain the multidirectional mechanism of pharmacological action of triazoloacridinone derivatives at all. Thus, the aim of the current work was to predict oxidative pathways of C-1305 that would reflect its phase I metabolism. The...
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C2 NIWA Community-Segmentation Criteria and Building Brand Associations on the Example of a Selected Target Group
PublicationEvery organization which offers products or services wishes to communicate with their customers in the most effective way. This kind of communication is based on proper selection of target groups, which are extracted in the process of market segmentation. That is way it is very important to ask the question to whom the message is to be directed and what kind of message we want to give. This article describes the selection criteria...
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Abdominal Aortic Aneurysm segmentation from contrast-enhanced computed tomography angiography using deep convolutional networks
PublicationOne of the most common imaging methods for diagnosing an abdominal aortic aneurysm, and an endoleak detection is computed tomography angiography. In this paper, we address the problem of aorta and thrombus semantic segmentation, what is a mandatory step to estimate aortic aneurysm diameter. Three end-to-end convolutional neural networks were trained and evaluated. Finally, we proposed an ensemble of deep neural networks with underlying...
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MSIS sonar image segmentation method based on underwater viewshed analysis and high-density seabed model
PublicationHigh resolution images of Mechanically Scanned Imaging Sonars can bring detailed representation of underwater area if favorable conditions for acoustic signal to propagate are provided. However to properly asses underwater situation based solely on such data can be challenging for less than proficient interpreter. In this paper we propose a method to enhance interpretative potential of MSIS image by dividing it in to subareas depending...
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Dependence of Power Characteristics on Savonius Rotor Segmentation
PublicationSavonius rotors are large and heavy because they use drag force for propulsion. This leads to a larger investment in comparison to horizontal axis wind turbine (HAWT) rotors using lift forces. A simple construction of the Savonius rotor is preferred to reduce the production effort. Therefore, it is proposed here to use single-segment rotors of high elongation. Nevertheless, this rotor type must be compared with a multi-segment...
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Tea and Liver Antioxidant Capabilities in Ethanol Toxicity
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Segmentation of Passenger Electric Cars Market in Poland
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Coffee Consumer Segmentation: Implications for Producers and Sellers
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MRI assessment of ectopic fat accumulation in pancreas, liver and skeletal muscle in patients with obesity, overweight and normal BMI in correlation with the presence of central obesity and metabolic syndrome
PublicationPurpose: Obesity, defined as a body mass index (BMI) exceeding 30 kg/m2, is a serious health problem, which can be called an epidemic on a global scale and is one of the most important causes of preventable death. The aim of this study was to assess ectopic fat accumulation in pancreas, liver and skeletal muscle in patients with obesity, overweight and normal BMI in correlation with metabolic syndrome (MetS). Patients and methods:...
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Wilms’ tumour-the reality of tissue analysis in the Polish Paediatric Solid Tumours Group
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Regarding the “Tumour spillage of the pleomorphic adenoma of the parotid gland: A proposal for intraoperative measures”
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Is the Fatty Acids Profile in Blood a Good Predictor of Liver Changes? Correlation of Fatty Acids Profile with Fatty Acids Content in the Liver
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RFM-based repurchase behavior for customer classification and segmentation
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Editorial “Nutrition and Dietary Intake for Liver-Related Diseases”
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Pathomorphology of the Liver in Dogs with Clinical Signs of Portosystemic Shunts
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The significance of VEGF-C/VEGFR-2 interaction in the neovascularization and prognosis of nephroblastoma (Wilms' tumour)
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A Robust Method for Sample Preparation of Gastrointestinal Stromal Tumour for LC/MS Untargeted Metabolomics
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Detection ofHelicobacterspecies in liver and stomach tissues of patients with chronic liver diseases using polymerase chain reaction-denaturing gradient gel electrophoresis and immunohistochemistry
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Eicosanoids in Nonalcoholic Fatty Liver Disease (NAFLD) Progression. Do Serum Eicosanoids Profile Correspond with Liver Eicosanoids Content during NAFLD Development and Progression?
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Potentiation of the anti-tumour effects of Photofrin®-based photodynamic therapy by localized treatment with G-CSF
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Volatile organic compounds in gastrointestinal stromal tumour tissue originating from patient-derived xenografts
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Multi-objective design of miniaturized impedance transformers by domain segmentation
PublicationFast multi-objective design optimization of compact microstrip impedance transformers is discussed. Our approach exploits approximation models constructed using sampled coarse- mesh EM simulation data in a partitioned design space and response correction techniques for design refinement. Demonstra
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DentalSegmentator: robust deep learning-based CBCT image segmentation
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Segmentation of Coffee Consumers Using Sustainable Values: Cluster Analysis
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Active Contour Method for Segmentation of the Glands in Colon Histology Images
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DCANet: deep context attention network for automatic polyp segmentation
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Spectrum of Epithelial-Mesenchymal Transition Phenotypes in Circulating Tumour Cells from Early Breast Cancer Patients
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Detection of Helicobacter rodentium-like DNA in the liver tissue of patients with chronic liver diseases by polymerase chain reaction–denaturing gradient gel electrophoresis and DNA sequence analysis
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Application of colour image segmentation for localization and extraction text from images
PublicationW otaczającym nas świecie informacja tekstowa odgrywa wielką rolę. W postaci tekstowej podawane są: nazwy ulic, nazwy sklepów i instytucji, opisy przedmiotów np. tytuły książek, opakowań itp. Jednocześnie współczesne programy komputerowe służące do rozpoznawania tekstu (OCR) ''nie radzą sobie'' z analizą obrazów otrzymanaych za pomocą kamer. Segmentacja obrazu z następującą kontekstową analizą parametrów segmentów może dostarczyć...
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Effects of some antibiotics on glucose 6-phosphate dehydrogenase in sheep liver
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Iron overload and HFE gene mutations in Polish patients with liver cirrhosis
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Proteome changes upon in ovo stimulation with Lactobacillus synbiotic in chicken liver
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Quantitative proteomic analysis of anticancer drug RH1 resistance in liver carcinoma
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Antoxidant enzymes in the liver and gills ofTinca tincafrom various water bodies
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Metabolic transformation of antitumor agent C1311 with various fractions of rat liver.
PublicationWykazano, że enzymatyczna aktywacja jest konieczna dla aktywności bilogicznej pochodnej C-1311. Zbadano przemiany związku w obecności różnych frakcji enzymatycznych mikrosomalnych komórek wątroby szczura.Badania te wykazały, że związek C-1311 jest bardziej podatny na transformację pod wpływem frakcji aktywowanych enzymów mikrosomalnych (CYP1A, CYP2B, CYP3A i CYP4A) niż frakcji S9, cytozolowej czy mikrosomów nieaktywowanych. Związek...
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Detoxification of the tricyclic antidepressant opipramol and its analog – IS-noh by UGT enzymes before and after activation by phase I enzymes in rat liver microsomes
PublicationThe present studies were carried out to evaluate the simultaneous one-pot metabolism of opipramol (IS-opi) and analog (IS-noh) by phase I and phase II enzymes present in rat liver microsomes (RLM) as an alternative to separate testing with recombinant enzymes. This approach allows for more time-saving and cost-effective screening of the metabolism of newly discovered drugs. We also considered that the lack of results for phase...
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Organotin compounds in the liver tissue of marine mammals from the PolishCoast of the Baltic Sea.
PublicationOznaczono zawartość związków cynoorganicznych w próbkach wątrób pochodzących od ssaków morskich złowionych w polskiej strefie ekonomicznej Morza Bałtyckiego. W ramach przeprowadzonych badań opracowana została oryginalna metodyka analityczna. Całkowite stężenie związków z tej grupy wahało się w granicach od 43,9 do 7698 ng Sn/g próbki (w przeliczeniu na suchą masę). Badano zależność stężeń tych związków od wieku i płci osobników.
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Comparison of Deep Neural Network Learning Algorithms for Mars Terrain Image Segmentation
PublicationThis paper is dedicated to the topic of terrain recognition on Mars using advanced techniques based on the convolutional neural networks (CNN). The work on the project was conducted based on the set of 18K images collected by the Curiosity, Opportunity and Spirit rovers. The data were later processed by the model operating in a Python environment, utilizing Keras and Tensorflow repositories. The model benefits from the pretrained...
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Effect of sweet grass extract against oxidative stress in rat liver and serum
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Keratin 7 expression in lymph node metastases but not in the primary tumour correlates with distant metastases and poor prognosis in colon carcinoma
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Modulation of CYP3A4 activity and induction of apoptosis, necrosis and senescence by the anti-tumour imidazoacridinone C-1311 in human hepatoma cells
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Analysis of Mitochondrial Genome from Labrador (Canis lupus familiaris) with Mammary Gland Tumour Reveals Novel Mutations and Polymorphisms
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In vitro enzyme kinetics and NMR-based product elucidation for glutathione S-conjugation of the anticancer unsymmetrical bisacridine C-2028 in liver microsomes and cytosol: major role of glutathione S-transferase M1-1 isoenzyme
PublicationThis work is the next step in studying the interplay between C-2028 (anticancer-active unsymmetrical bisacridine developed in our group) and the glutathione S-transferase/glutathione (GST/GSH) system. Here, we analyzed the concentration- and pH-dependent GSH conjugation of C-2028 in rat liver microsomes and cytosol. We also applied three recombinant human GST isoenzymes, which altered expression was found in various tumors. The...
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Segmentation Quality Refinement in Large-Scale Medical Image Dataset with Crowd-Sourced Annotations
PublicationDeployment of different techniques of deep learning including Convolutional Neural Networks (CNN) in image classification systems has accomplished outstanding results. However, the advantages and potential impact of such a system can be completely negated if it does not reach a target accuracy. To achieve high classification accuracy with low variance in medical image classification system, there is needed the large size of the...
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Liver steatosis correlates with iron overload but not with HFE gene mutations in chronic hepatitis C
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Effects of Resveratrol Supplementation in Patients with Non-Alcoholic Fatty Liver Disease—A Meta-Analysis
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Metabolic transformations of antitumor imidazoacridinone, C-1311, with microsomal fractions of rat and human liver
PublicationWykazano, że enzymatyczna aktywacja jest konieczna dla aktywności biologicznej pochodnej C-1311 (Symadex R), która znajduje się w II fazie badań klinicznych. Zbadano przemiany enzymatyczne tego związku w obecności frakcji enzymatycznych mikrosomalnych komórek wątroby szczura i ludzkiej. Badania te wykazały, że związek C-1311 jest bardziej podatny na przemiany w obecności frakcji mikrosomalnej niż S9 i cytozolowej. Inkubacja związku...