Search results for: MULTICELLULAR TUMOR SPHEROIDS

• Mixed germ cell tumor - Male, 31 - Tissue image [6060730023674551]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of TESTIS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Mixed germ cell tumor - Male, 31 - Tissue image [6060730023673761]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of TESTIS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Mixed germ cell tumor - Male, 31 - Tissue image [6060730023672131]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of TESTIS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Mixed germ cell tumor - Male, 31 - Tissue image [6060730023676811]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of TESTIS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Mixed germ cell tumor - Male, 31 - Tissue image [6060730023678671]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of TESTIS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Mixed germ cell tumor - Male, 31 - Tissue image [606073002367571]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of TESTIS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Mixed germ cell tumor - Male, 31 - Tissue image [6060730023679851]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of TESTIS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Mixed germ cell tumor - Male, 31 - Tissue image [6060730023675861]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of TESTIS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Mixed germ cell tumor - Male, 31 - Tissue image [6060730023673321]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of TESTIS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Mixed germ cell tumor - Male, 31 - Tissue image [6060730023678721]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of TESTIS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Mixed germ cell tumor - Male, 31 - Tissue image [6060730023676491]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of TESTIS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Mixed germ cell tumor - Male, 31 - Tissue image [6060730023671541]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of TESTIS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Mixed germ cell tumor - Male, 31 - Tissue image [7040247104939551]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of TESTIS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Mixed germ cell tumor - Male, 31 - Tissue image [6060730023674471]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of TESTIS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Synthesis of functionalized new conjugates of batracylin with tuftsin/ retro-tuftsin derivatives and their biological evaluation

  Publication

  • W. Januchta
  • M. Serocki
  • K. Dzierzbicka
  • G. Cholewiński
  • A. Składanowski

  - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - Year 2015

  New batracylin conjugates with tuftsin/retro-tuftsin derivatives were designed and synthesized using T3P as a coupling agent. The conjugates possess an amide bond formed between the carboxyl group of heterocyclic molecule and the N-termini of the tuftsin/retro-tuftsin chain. The in vitro cytotoxic activity of the new analogues and their precursors was evaluated using a series of human and murine tumor cells. BAT conjugates containing...

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• Giant cell tumor of bone, NOS - Female, 15 - Tissue image [5060730012985341]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BONES, JOINTS AND ARTICULAR CARTILAGE OF LIMBS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Giant cell tumor of bone, NOS - Female, 15 - Tissue image [50607300129831]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BONES, JOINTS AND ARTICULAR CARTILAGE OF LIMBS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Giant cell tumor of bone, NOS - Female, 15 - Tissue image [5060730012992961]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BONES, JOINTS AND ARTICULAR CARTILAGE OF LIMBS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Giant cell tumor of bone, NOS - Female, 15 - Tissue image [5060730012989231]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BONES, JOINTS AND ARTICULAR CARTILAGE OF LIMBS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Giant cell tumor of bone, NOS - Female, 15 - Tissue image [5060730012987211]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BONES, JOINTS AND ARTICULAR CARTILAGE OF LIMBS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Giant cell tumor of bone, NOS - Female, 15 - Tissue image [5060730012989901]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BONES, JOINTS AND ARTICULAR CARTILAGE OF LIMBS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Giant cell tumor of bone, NOS - Female, 15 - Tissue image [5060730012986001]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BONES, JOINTS AND ARTICULAR CARTILAGE OF LIMBS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Giant cell tumor of bone, NOS - Female, 15 - Tissue image [5060730012996791]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BONES, JOINTS AND ARTICULAR CARTILAGE OF LIMBS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Reduced expression of ELAVL4 in male meningioma patients

  Publication

  • R. Stawski
  • S. Piaskowski
  • E. Stoczynska-Fidelus
  • K. Wozniak
  • M. Bienkowski
  • M. Zakrzewska
  • M. Witusik-Perkowska
  • D. Jaskolski
  • W. Och
  • W. Papierz... and 3 others

  - Brain Tumor Pathology - Year 2013

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• Medical Image Dataset Annotation Service (MIDAS)

  Publication

  • B. Klaudel
  • A. Obuchowski
  • B. Rydziński
  • R. Karski
  • P. Syty
  • P. Jasik
  • M. Glembin

  - Year 2020

  MIDAS (Medical Image Dataset Annotation Service) is a custom-tailored tool for creating and managing datasets either for deep learning, as well as machine learning or any form of statistical research. The aim of the project is to provide one-fit-all platform for creating medical image datasets that could easily blend in hospital's workflow. In our work, we focus on the importance of medical data anonimization, discussing the...

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• Imidazoacridinone-dependent lysosomal photodestruction: a pharmacological Trojan horse approach to eradicate multidrug-resistant cancers

  Publication

  • Y. Adar
  • M. Stark
  • E. E. Bram
  • P. Nowak-Sliwinska
  • H. van den Bergh
  • G. Szewczyk
  • T. Sarna
  • A. Skladanowski
  • A. Griffoen
  • Y. G. Assaraf

  - Cell Death and Disease - Year 2012

  Multidrug resistance (MDR) remains a primary hindrance to curative cancer therapy. Thus, introduction of novel strategies to overcome MDR is of paramount therapeutic significance. Sequestration of chemotherapeutics in lysosomes is an established mechanism of drug resistance. Here, we show that MDR cells display a marked increase in lysosome number. We further demonstrate that imidazoacridinones (IAs), which are cytotoxic fluorochromes,...

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• ANALYSIS OF THE p53 PROTEIN GENE EXPRESSION MODEL

  Publication

  • A. Bartłomiejczyk
  • M. Bodnar
  • M. Piotrowska

  - Year 2015

  We study the asymptotic behaviour of the solutions of the p53-Mdm2 model proposed by Monk (2003). The p53 gene is crucial for cellular inhibition of the angiogenesis process, while Mdm2 is a negative regulator of the p53 tumor-suppressor. We investigate the stability of the positive steady state and perform some numerical experiments.

• Modulation of UDP-glucuronidation by acridinone antitumor agents C-1305 and C-1311 in HepG2 and HT29 cell lines, despite slight impact in noncellular systems.

  Publication

  • A. Bejrowska
  • M. Pawłowska
  • A. Mróz
  • Z. Mazerska

  - Pharmacological Reports - Year 2018

  Background Among the studied antitumor acridinone derivatives developed in our laboratory, 5-dimethylaminopropylamino-8-hydroxytriazoloacridinone (C-1305) and 5-diethylaminoethylamino-8-hydroxyimidazoacridinone (C-1311) exhibited cytotoxic and antitumor properties against several cancer types and were selected to be evaluated in preclinical and early-phase clinical trials. In the present work, we investigated the impact of C-1305...

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• Selected adipocytokines in patients with an incidentally discovered pheochromocytoma

  Publication

  • M. F. Kaszubowski
  • A. Babińska
  • P. Kmieć
  • K. Sworczak

  - Minerva Endocrinologica - Year 2020

  BACKGROUND: Adipose tissue secretes many adipokines and cytokines, which may be an additional risk factor of cardiovascular and metabolic diseases in patients with an incidentally discovered pheochromocytoma (PHEO). The aim of the study was to investigate levels of selected adipocytokines in these patients. METHODS: This prospective study included 12 patients with an incidentally discovered PHEO and 18 healthy participants. In...

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• Solid Phase Synthesis and Biological Activity of Tuftsin Conjugates

  Publication

  • M. Kukowska-Kaszuba
  • K. Dzierzbicka
  • M. Serocki
  • A. Składanowski

  - JOURNAL OF MEDICINAL CHEMISTRY - Year 2011

  New tuftsin/retro-tuftsin conjugates were designed and synthesized using a classical fluorenylmethoxycarbonyl (Fmoc) solid phase procedure. All the peptide conjugates were divided into three series: 1,4-dihydroxyanthraquinone (type A), 1-nitroacridine (type B), and 4-carboxyacridone (type C) derivatives. In type A conjugates, the N-terminal group of the peptide chain is directly connected to the anthraquinone ring at C1 (Scheme...

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• Effect Of Resveratrol And Quercetin On Telomerase Regulation In Cancer Cells And Their Anti-Cancer Potential

  Publication

  • W. Brankiewicz

  - Year 2019

  Telomeres and telomerase are nowadays one on targets for anticancer therapy. Telomerase is expressed in ~90% of human cancer cell lines and tumor specimens, whereas its enzymatic activity is not detectable in most human somatic cells. Was found that some dietary compounds can modulate telomerase activity in cancer cells. This review summarizes the current knowledge about the effects of resveratrol and quercetin on telomerase regulation...

• Biodiversity of microorganisms in the Baltic Sea: the power of novel methods in the identification of marine microbes

  Publication

  • B. Krawczyk
  • A. Łuczkiewicz
  • K. Jankowska

  - FEMS MICROBIOLOGY REVIEWS - Year 2024

  Until recently, the data on the diversity of the entire microbial community from the Baltic Sea were relatively rare and very scarce. However, modern molecular methods have provided new insights into this field with interesting results. They can be summarized as follows. (i) Although low salinity causes a reduction in the biodiversity of multicellular species relative to the populations of the North–East Atlantic, no such reduction...

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• Wilms tumor - Male, 2 - Tissue image [521073003181761]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Wilms tumor - Male, 7 - Tissue image [5210730031816721]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Wilms tumor - Male, 7 - Tissue image [5210730031815061]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Wilms tumor - Male, 7 - Tissue image [5210730031814781]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Wilms tumor - Male, 7 - Tissue image [5210730031817471]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Wilms tumor - Male, 7 - Tissue image [5210730031818841]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Wilms tumor - Male, 7 - Tissue image [5210730031815921]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Wilms tumor - Male, 7 - Tissue image [5210730031817921]

  Open Research Data

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Wilms tumor - Male, 7 - Tissue image [5210730031815801]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Wilms tumor - Male, 7 - Tissue image [5210730031815741]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Wilms tumor - Male, 7 - Tissue image [5210730031815811]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Wilms tumor - Male, 7 - Tissue image [5210730031813611]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Wilms tumor - Male, 7 - Tissue image [5210730031811771]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Wilms tumor - Male, 7 - Tissue image [5210730031812891]

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  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Wilms tumor - Male, 7 - Tissue image [5210730031811661]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Wilms tumor - Male, 7 - Tissue image [5210730031815771]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Wilms tumor - Male, 7 - Tissue image [5210730031811121]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Wilms tumor - Male, 2 - Tissue image [5040730028006491]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.