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Search results for: ANTIBIOTIC RESISTANCE GENES
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Long-term measurement of physiological parameters - a teenager (60 minutes) 3 serie
Open Research DataThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.Long-term (60 minutes) measurement of physiological parameters was performed on the healthy...
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Long-term measurement of physiological parameters - a teenager (60 minutes) 6th serie
Open Research DataThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.Long-term (60 minutes) measurement of physiological parameters was performed on the healthy...
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Long-term measurement of physiological parameters - a teenager (60 minutes) 5 serie
Open Research DataThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.Long-term (60 minutes) measurement of physiological parameters was performed on the healthy...
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Long-term measurement of physiological parameters - a teenager (60 minutes) 1 serie
Open Research DataThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.Long-term (60 minutes) measurement of physiological parameters was performed on the healthy...
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Long-term measurement of physiological parameters - a teenager (60 minutes) 12. series
Open Research DataThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.Long-term (60 minutes) measurement of physiological parameters was performed on the healthy...
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Long-term measurement of physiological parameters - a teenager (4h)
Open Research DataThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.Long-term (4 hours) measurement of physiological parameters was performed on the healthy volunteer...
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Long-term measurement of physiological parameters - a teenager (60 minutes) 11. series
Open Research DataThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.Long-term (60 minutes) measurement of physiological parameters was performed on the healthy...
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Long-term measurement of physiological parameters - a teenager (60 minutes) 2 serie
Open Research DataThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.Long-term (60 minutes) measurement of physiological parameters was performed on the healthy...
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Long-term measurement of physiological parameters - a teenager (60 minutes) 7th serie
Open Research DataThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.Long-term (60 minutes) measurement of physiological parameters was performed on the healthy...
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Long-term measurement of physiological parameters - a teenager (60 minutes) 10th series
Open Research DataThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.Long-term (60 minutes) measurement of physiological parameters was performed on the healthy...
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Long-term measurement of physiological parameters - a teenager (150 minutes) 1 serie
Open Research DataThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.Long-term (up to 150 minutes) measurement of physiological parameters was performed on the healthy...
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Long-term measurement of physiological parameters - a teenager (13h)
Open Research DataThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.Long-term (13 hours) measurement of physiological parameters was performed on the healthy volunteer...
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Long-term measurement of physiological parameters - a teenager (60 minutes) 9th serie
Open Research DataThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.Long-term (60 minutes) measurement of physiological parameters was performed on the healthy...
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Long-term measurement of physiological parameters - a teenager (60 minutes) 4 serie
Open Research DataThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.Long-term (60 minutes) measurement of physiological parameters was performed on the healthy...
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Long-term measurement of physiological parameters - a teenager (60 minutes) 8th serie
Open Research DataThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.Long-term (60 minutes) measurement of physiological parameters was performed on the healthy...
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Long-term measurement of physiological parameters - a teenager (10h)
Open Research DataThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.Long-term (10 hours) measurement of physiological parameters was performed on the healthy volunteer...
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Long-term measurement of physiological parameters - a teenager (60 minutes) 3 serie
Open Research DataThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.Long-term (60 minutes) measurement of physiological parameters was performed on the healthy...
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Recurrent bowel-blood translocations of Escherichia coli with the unique virulence characteristics over three-year period in the patient with acute myeloid leukaemia – case report
PublicationIn patients with haematological malignancies, the bowel remains the main source of Escherichia coli bloodstream infections. We present the clinical example of recurrent bowel-blood translocations of E. coli with the unique virulence characteristics in a 55-year-old male with the diagnosis of acute myeloid leukaemia. The virulent factors profile of examined strains confirmed that the co-existence of genes papC, sfa, usp and cnf1,...
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cDNA fingerprint from the hepatopancreatic glands of pond snails (Lymnaea stagnalis) exposed to benzo[a]pyrene
PublicationIdentification of differentially expressed genes that could be potentially used as biomarkers of PAH exposure of common invertebrate animal (like freshwater snail) would be a valuable resource for investigators interested in toxicology and biomonitoring of aquatic environments. Therefore, the aim of this research was to investigate effects of waterborne benzo[a]pyrene (B[a]P) exposure on mRNA expression in the pond snail’s (Lymnaea...
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Hydrogen effects in duplex stainless steel welded joints - electrochemical studies
PublicationIn this work results on the influence of hydrogen on passivity and corrosion resistance of 2205 duplex stainless steel (DSS) welded joints are described. The results were discussed by taking into account three different areas on the welded joint: weld metal (WM), heat-affected zone (HAZ) and parent metal. The corrosion resistance was qualified with the polarization curves registered in a synthetic sea water. The conclusion is that,...
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Effect of MAO coatings on cavitation erosion and tribological properties of 5056 and 7075 aluminum alloys
PublicationTwo ceramic coatings have been applied on 5056 and 7075 aluminum alloy by microarc oxidation (MAO) technology. The mass losses, surface morphologies and the phase constituents of the MAO coatings before and after cavitation tests were examined by means of digital scales, scanning electron microscopy (SEM) and X-ray diffraction (XRD), respectively. In order to assess the impact of the mechanical properties of the surface layer on...
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Review on Current Status of Echinocandins Use
PublicationFungal infections are rising all over the world every year. There are only five medical compound classes for treatment: triazoles, echinocandins, polyenes, flucytosine and allylamine. Currently, echinocandins are the most important compounds, because of their wide activity spectrum and much lower sides effects that may occur during therapy with other drugs. Echinocandins are secondary metabolites of fungi, which can inhibit the...
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Imunofan - RDKVYR peptide - stimulates skin cell proliferation and promotes tissue repair
PublicationRegeneration and wound healing are vital to tissue homeostasis and organism survival. One of the biggest challenges of today's science and medicine is finding methods and factors to stimulate these processes in the human body. Effective solutions to promote regenerative responses will accelerate advances in tissue engineering, regenerative medicine, transplantology, and a number of other clinical...
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The retrofitting of ships by applying retractable bow hydrofoils: a case study
PublicationIncreasing environmental requirements and a relatively long ship life of 30 years mean more attention is needed to retrofit existing ships. One possibility is using hydrofoils to reduce the ship’s resistance and improve comfort and safety in rough sea conditions. This study investigates the influence of retractable bow hydrofoils on the seakeeping performance and operational conditions of a selected case study vessel (V-shaped...
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Further development of the poroelastic road surface within the new Polish project SEPOR
PublicationRoad surfaces have a direct impact on noise generated by rolling tyres, the main and dominant source of noise of moving vehicles. Road surface texture, porosity and stiffness/elasticity govern the pavement contribution to tyre/road noise the most. An experimental PoroElastic Road Surface (PERS) is a wearing course with a high content of interconnected voids (pores) and with an elastic behavior due to the use of small particles...
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Long-term measurement of physiological parameters - a teenager (9h and 20min)
Open Research DataThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.Long-term (9 hours and 20 minutes) measurement of physiological parameters was performed on...
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Usage of Two-Center Basis Function Neural Classifiers in Compact Smart Resistive Sensors
PublicationA new solution of the smart resistance sensorwith the Two-Center Basis Function (TCBF) neuralclassifier, for which the resistance sensor is a component ofan anti-aliasing filter of an ADC is proposed. Thetemperature measurement procedure is based on excitationof the filter by square impulses, sampling time response ofthe filter and processing measured voltage values by theTCBF classifier. All steps of the measurement procedure...
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UV-Light-Induced Fluctuation Enhanced Sensing by WO3-Based Gas Sensors
PublicationWO3-based gas sensors were investigated under UV-light irradiation and at different working temperatures with the object of achieving superior sensitivity and selectivity. Resistance fluctuations in the WO3 layer were studied together with dc resistance measurements. The data were taken in synthetic air, ethanol, nitrogen dioxide, and mixtures of these gases. We conclude that UV irradiation can easily be applied to enhance the...
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Cavitation Erosion – Phenomenon and Test Rigs
PublicationThe cavitation and cavitation erosion phenomenon have been shortly presented. The main four types of test rigs to investigate the cavitation erosion resistance have been shown. Each type of test design is described and an example of a design is shown. A special attention has been payed to the designs described in the International ASTM Standards: a vibratory design and a cavitating jet cell. There was shown that the design of a...
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A measurement method for lossy capacitive relative humidity sensors based on a direct sensor-to-microcontroller interface circuit
PublicationA new time-domain measurement method for determining the capacitance and resistance values of lossy relative humidity capacitive sensors is presented. The method is based on a direct sensor-to-microcontroller interface for microcontrollers with internal analog comparators and timers. The interface circuit consists only of four reference resistors (two reference resistors if a microcontroller includes a voltage reference source),...
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Electrical and noise responses of carbon nanotube networks enhanced by UV light for detection of organic gases (ethanol, acetone)
Open Research DataCarbon nanotube networks of different optical transparencies were investigated via resistance and 1/f noise measurements for detection of ethanol and acetone. The sensor resistive and noise responses were collected for dark and UV-assisted conditions, revealing the improvement in sensor sensitivity and limit of detection after applying UV light (275...
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Comparative molecular modelling of biologically active sterols
PublicationMembrane sterols are targets for a clinically important antifungal agent – amphotericin B. The relatively specific antifungal action of the drug is based on a stronger interaction of amphotericin B with fungal ergosterol than with mammalian cholesterol. Conformational space occupied by six sterols has been defined using the molecular dynamics method to establish if the conformational features correspond to the preferential interaction...
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Analytical approach for membrane action in laterally-restrained reinforced concrete square slabs under uniformly distributed loads
PublicationLaterally-restrained reinforced concrete slabs can mobilise compressive membrane action and subsequent tensile membrane action under extreme loading conditions, thereby enhancing the load resistance under uniformly distributed loads. Previous analytical study focuses primarily on tensile membrane action in simply-supported slabs. This paper describes an analytical approach for membrane action in laterally-restrained square slabs....
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Charakterystyka oporności Klebsiella pneumoniae New Delhi na karbapenemy
PublicationBakterie Klebsiella pneumoniae New Delhi, posiadające gen oporności na karbapenemy (blaNDM) zostały po raz pierwszy wyizolowane w 2008 roku w Szwecji od pacjenta wcześniej hospitalizowanego w Indiach. Bakterie te szybko rozprzestrzeniają się po całym świecie, a od 2011 roku występują również w Polsce. Stanowią one wysokie ryzyko epidemiologiczne, ponieważ gen oporności na karbapenemy przekazywany jest pomiędzy bakteriami poprzez...
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MutS3: a MutS homologue of unknown biological function
PublicationThe homologues of MutS proteins are widespread among both Prokaryotes and Eukaryotes. MutS designated as MutS1 is a part of MMR (mismatch repair) system which is responsible for removal of mispaired bases and small insertion/deletion loops in DNA. Initially, the only MutS homologues known were those engaged in mismatch repair and these were later designated as MutS1. Subsequently, the MutS2 homologue was distinguished. MutS2 does...
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Detection of Polish clinical Aspergillus fumigatus isolates resistant to triazoles
PublicationWe studied the presence of triazole resistance of 121 Aspergillus fumigatus clinical isolates collected in two Polish cities, Warsaw and Wrocław, to determine if resistance is emerging in our country. We identified five itraconazole resistant isolates (4.13%) carrying the TR34/L98H alteration in Cyp51A gene, four of which were cross-resistant to posaconazole and one to voriconazole. One isolate was intermediate susceptible to itraconazole...
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Changes in gene methylation patterns in neonatal murine hearts: Implications for the regenerative potential
PublicationBackground The neonatal murine heart is able to regenerate after severe injury; this capacity however, quickly diminishes and it is lost within the first week of life. DNA methylation is an epigenetic mechanism which plays a crucial role in development and gene expression regulation. Under investigation here are the changes in DNA methylation and gene expression patterns which accompany the loss of regenerative potential. Results The...
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Folate/homocysteine metabolism and lung cancer risk among smokers
PublicationBackground: Folate and homocysteine are involved in DNA synthesis and methylation processes, which are deregulated during carcinogenesis. Objectives: The aim of this study was to assess the relationship between folate/homocysteine concentrations, the functional polymorphisms of folate/homocysteine genes and lung cancer risk among cigarette smokers. Study design: The study included 132 lung cancer patients and 396 controls from...
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Transcriptomic landscape of blood platelets in healthy donors
PublicationBACKGROUND Blood platelet RNA-sequencing is increasingly used among the scientific community. Aberrant platelet transcriptome is common in cancer or cardiovascular disease, but reference data on platelet RNA content in healthy individuals are scarce and merit complex investigation. METHODS We sought to explore the dynamics of platelet transcriptome. Datasets from 204 healthy donors were used for the analysis of splice variants,...
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Mechanical and Microstructural Characterization of TIG Welded Dissimilar Joints between 304L Austenitic Stainless Steel and Incoloy 800HT Nickel Alloy
PublicationIn this article, the mechanical properties and microstructure of 304L austenitic stainless steel/Incoloy 800HT nickel alloy dissimilar welded joints are investigated. The joints were made of 21.3 mm × 7.47 mm tubes using the TIG process with the use of S Ni 6082 nickel filler metal. No welding imperfections were found and high strength properties of joints were obtained, meeting the assumed acceptance criteria of the product’s...
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Hydrogen Damage in Superaustenitic 904L Stainless Steels
Publicationresults on the influence of hydrogen on corrosion resistance and of hydrogen embrittlement of 904L superaustenitic stainless steel were investigated. The cracking behavior was studied by performing a slow strain rate test in synthetic seawater under varying cathodic polarization conditions. The results showed that the steel’s plasticity varied with the applied cathodic current density. Significant reductions in ductility were found,...
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Drug-resistant and hospital-associated Enterococcus faecium from wastewater, riverine estuary and anthropogenically impacted marine catchment basin.
PublicationEnterococci, ubiquitous colonizers of humans and other animals, play an increasingly important role in health-care associated infections (HAIs). Acquisition of resistance determinants not only seriously limits available therapeutic options but also increases available gene pool for other species. It is believed that the recent evolution of two clinically relevant species, Enterococcus faecalis and Enterococcus faecium occurred...
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Effect of cobalt addition on the corrosion behaviorof near equiatomic NiTi shape memory alloy in normal saline solution: electrochemical and XPS studies
PublicationThe electrochemical and corrosion (uniform and localized) behavior of a binary Ni52Ti48 shape memory alloy (SMA) and two ternary Ni52Ti48-xCox (x = 1.5 and 4.0 wt.%) SMAs were studied. Measurements were conducted in 0.9% NaCl solution at 37 oC employing various electrochemical methods. These include: linear polarization resistance (LPR), linear sweep voltammetry (LSV), chronoamperometry and dynamic electrochemical impedance spectroscopy...
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Nickel-nanodiamond coatings electrodeposited from tartrate electrolyte at ambient temperature
PublicationIn this study, nanocrystalline Ni and Ni-diamond coatings were obtained by electrodeposition from tartrate electrolyte at ambient temperature aiming at improving corrosion and wear properties of the material. The created surfaces were investigated with regard to microhardness, adhesion, wear- and corrosion-resistance. The various methods such as atomic force microscopy, scanning electron microscopy, electrochemical impedance spectroscopy...
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Mechanical durability and electroanalytical performance of 3D-printed multi-material sensors
Open Research DataThe data set consists tensile strength, electric resistance, electrochemical characteristics and physicochemical studies of multi-material 3D printed systems, including their sensing performance during detection of antibiotics in an industrial sewage. Additionally, contact angle measurements and SEM micrographs of the electrode surfaces were included.
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Quest for the Molecular Basis of Improved Selective Toxicity of All-Trans Isomers of Aromatic Heptaene Macrolide Antifungal Antibiotics
PublicationThree aromatic heptaene macrolide antifungal antibiotics, Candicidin D, Partricin A (Gedamycin) and Partricin B (Vacidin) were subjected to controlled cis-trans to all trans photochemical isomerization. The obtained all-trans isomers demonstrated substantially improved in vitro selective toxicity in the Candida albicans cells: human erythrocytes model. This effect was mainly due to the diminished hemotoxicity. The molecular modeling...
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Natural Products Counteracting Cardiotoxicity during Cancer Chemotherapy: The Special Case of Doxorubicin, a Comprehensive Review
PublicationCardiotoxicity is a frequent undesirable phenomenon observed during oncological treatment that limits the therapeutic dose of antitumor drugs and thus may decrease the effec-‐‑ tiveness of cancer eradication. Almost all antitumor drugs exhibit toxic properties towards cardiac muscle. One of the underlying causes of cardiotoxicity is stimulation of oxidative...
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Ciprofloxacin-modified degradable hybrid polyurethane-polylactide porous scaffolds developed for potential use as an antibacterial scaffold for regeneration of skin
PublicationThe aim of the performed study was to fabricate an antibacterial and degradable scaffold that may be used in the field of skin regeneration. To reach the degradation criterion for the biocompatible polyurethane (PUR), obtained by using amorphous α,ω-dihydroxy(ethylene-butylene adipate) macrodiol (PEBA), was used and processed with so-called “fast-degradable” polymer polylactide (PLA) (5 or 10 wt %). To meet the antibacterial requirement...
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Degradation of protective coatings in steel chimneys of flue gas desulfurisation system
PublicationThis paper presents problems associated with corrosion of steel stacks and changes in philosophy of corrosion protection when implemented into flue gas desulphurization systems. In-situ tests were taken by means of electrochemical impedance spectroscopy at the stack which discharges flue gas before wet lime/limestone desulphurization. A very quick electrolyte absorption by the spherical infill vinylester coating was found using...
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Mechanical Properties of a Dike Formed from a Soil-ash Composite
PublicationThe paper presents the research results on application of composite soils for dike construction. The composite soil is produced by mixing bottom ash (by-product of energetics) with dredged material (sand) taken from the mouth of The Vistula river. The optimum composite for dike core was chosen with respect to mechanical parameters: high internal friction angle, good compaction and reduced hydraulic conductivity. The test dike was...