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Search results for: KURZ
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Relation of the polymorphism of cyp51A sequence and the susceptibility of Aspergillus fumigatus isolates to triazoles determined by commercial gradient test (Etest) and by reference methods
PublicationThe aim of this study was to evaluate the accuracy of commercial gradient test (Etest) in the detection of triazole resistant Aspergillus fumigatus isolates using reference microdilution methods and the analysis of sequences of the cyp 51A gene. The study was performed on twenty clinical isolates which were identified as Aspergillus fumigatus based on the DNA sequences of the ITS1-2 fragment of ribosomal DNA and the β-tubulin gene,...
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Essential Oils, Silver Nanoparticles and Propolis as Alternative Agents Against Fluconazole Resistant Candida albicans, Candida glabrata and Candida krusei Clinical Isolates
PublicationDevelopment of effective and safe therapeutic treatment of fungal infections remains one of the major challenge for modern medicine. The aim of presented investigation was to analyze the in vitro antifungal activity of selected essential oils, ethanolic extracts of propolis and silver nanoparticles dropped on TiO2 against azole-resistant C. albicans (n = 20), C. glabrata (n = 14) and C. krusei (n = 10) clinical isolates. Among...
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Comparative evaluation of new dihydropyrimidine and dihydropyridine derivatives perturbing mitotic spindle formation
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Activity of isavuconazole and other triazole derivatives against clinical isolates of Aspergillus fumigatus
PublicationAspergillus fumigatus is the most frequent pathogen of the genus Asperillus, which is highly susceptible to triazole derivatives, especially to isavuconazole and voriconazole. Many countries face a growing problem of infections due to A. fumigatus showing acquired resistance to one or several triazoles. In medical centres, monitoring the susceptibility of isolated Aspergillus spp. is recommended. The aim of this study was to collect...
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Antibacterial performance of nanocrystallined titania confined in mesoporous silica nanotubes
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Study on size effect of the silica nanospheres with solid core and mesoporous shell on cellular uptake
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In vitro and in vivo evaluation of sandwich-like mesoporous silica nanoflakes as promising anticancer drug delivery system
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Mesoporous silica nanoflakes – Biocompatibility, cellular uptake and drug transport
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Synthesis and Anticancer Activity of Mitotic-Specific 3,4-Dihydropyridine-2(1H)-thiones
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Detection of Polish clinical Aspergillus fumigatus isolates resistant to triazoles
PublicationWe studied the presence of triazole resistance of 121 Aspergillus fumigatus clinical isolates collected in two Polish cities, Warsaw and Wrocław, to determine if resistance is emerging in our country. We identified five itraconazole resistant isolates (4.13%) carrying the TR34/L98H alteration in Cyp51A gene, four of which were cross-resistant to posaconazole and one to voriconazole. One isolate was intermediate susceptible to itraconazole...
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Methodology of Selecting the Optimal Receptor to Create an Electrochemical Immunosensor for Equine Arteritis Virus Protein Detection
PublicationThe study reports a methodology of selecting the optimal receptor to create an electrochemical immunosensor for equine arteritis virus (EAV) protein detection. The detection was based on antigen recognition by antibodies immobilized on gold electrodes. Modification steps were controlled by electrochemical impedance spectroscopy and cyclic voltammetry measurements. In order to obtain the impedance immunosensor with the best parameters,...
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The Late Neolithic sepulchral and ritual place of site 14 in Kowal (Kuyavia, Central Poland)
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Polymorphisms in nucleotide excision repair genes and susceptibility to colorectal cancer in the Polish population
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MC1R common variants, CDKN2A and their association with melanoma and breast cancer risk
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Piagel
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CDKN2A common variant and multi-organ cancer risk—a population-based study
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Platinum group elements: a challenge for environmental analytics
PublicationW pracy opisano problemy związane z analityką platynowców (Platinum Group Elements - PGE) w próbkach środowiskowych (kurz uliczny, materia zawieszona, gleba i osady denne, wody, ścieki, próbki biologiczne). Scharakteryzowano poszczególne etapy procedury analitycznej mogące być źródłem błędów oraz powodować szereg trudności. Opisano sposoby pobierania, przechowywania i utrwalania próbek przeznaczonych do badań. Przedstawiono również...
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Der Begriff des Mythos bei Cassirer: zwischen UIdealismus, Ethnologie, politischer Philosophie und allgemeine Kulturphilosophie
PublicationDer Mythos war eines der bevorzugten Forschungsobjekte Cassirers, denen er zwei Bücher, zahlreiche Artikel und wichtige längere Aufsätze widmete. In diesem Artikel versuche ich Cassirers Mythendeutung kurz zu rekapitulieren, um ihre Position in der Gesamtheit seines philosophischen Systems festzulegen und ihr Erklärungspotenzial zu gewinnen. In erstem Teil handle ich das allgemeine Problem des mythischen Denkens hauptsächlich aufgrund...
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On Earth as in Universe
PublicationOn Earth as in Universe Ślady zostawione na podobraziu przygotowanym własnoręcznie przez Kazimierza Ostrowskiego. Kilka pociągnięć pędzlem ciemną farbą na odwrocie płótna, tu i ówdzie przyklejone włosy do powierzchni gruntu, kurz nagromadzony przez lata - słowem każdy element artefaktu, który trafił do mnie, był kapsułą czasu sprzed około pięćdziesięciu lat. Jedyne co mogłem zrobić, to wpisać drobiny obecności Kazimierza Ostrowskiego...
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Zanieczyszczenie modułu PV jako jeden z czynników spadku wydajności
PublicationModuły fotowoltaiczne są narażone na codzienne działanie czynników atmosferycznych, w tym osadzających się zanieczyszczeń. Nawet po niedługim czasie użytkowania odkładająca się w sposób naturalny warstwa zanieczyszczeń powoduje spadek sprawności konwersji energii promieniowania słonecznego na energię elektryczną.
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Outcomes of gynecologic cancer surgery during the COVID-19 pandemic: an international, multicenter, prospective CovidSurg-Gynecologic Oncology Cancer study
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Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study
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