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Search results for: auxcentic cell
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Radioimmunotherapy with 90Y-ibritumomab tiuxetan is a safe and efficient treatment for patients with B-cell lymphoma relapsed after auto-SCT: an analysis of the international RIT-Network
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Favourable outcomes in patients with early-stage non-small-cell lung cancer operated on by video-assisted thoracoscopic surgery: a propensity score-matched analysis†
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Destabilization of β‐Hemocyanin from Helix pomatia in Presence of Choline Amino Acids Results in Improved Cell Specificity and Cytotoxicity against Human Breast Cancer
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Analysis of carboxylic acid metabolites from the tricarboxylic acid cycle in Bacillus subtilis cell extract by capillary electrophoresis using an indirect photometric detection method
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Aberration of the enzymatic activity of Fhit tumor suppressor protein enhances cancer cell death upon photodynamic therapy similarly to that driven by wild-type Fhit
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Genes Involved in the Processes of Cell Proliferation, Migration, Adhesion, and Tissue Development as New Potential Markers of Porcine Granulosa Cellular Processes In Vitro: A Microarray Approach
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Down-regulation of DNA topoisomerase IIalpha leads to prolonged cell cycle transit in G2 and early M phases and increased survival to microtubule-interacting agents
PublicationInhibitory polimeryzacji mikrotubul wykazują preferencyjną toksyczność wobec komórek mitotycznych. W ramach tego projektu badaliśmy czy oporność komórek ludzkich białaczek na inhibitor mikrotubul, winkrystynę, prowadzi do zmian w regulacji progresji cyklu komórkowego. Nasze wyniki wskazują, że oporności na winkrystynę towarzyszą zmiany w długości fazy G2 i M w nieobecności i obecności inhibitora wrzeciona mitotycznego, nokodazolu....
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Fluconazole resistant Candida auris clinical isolates have increased levels of cell wall chitin and increased susceptibility to a glucosamine-6-phosphate synthase inhibitor
PublicationIn 2009 Candida auris was first isolated as fungal pathogen of human disease from ear canal of a patient in Japan. In less than a decade, this pathogen has rapidly spread around the world and has now become a major health challenge that is of particular concern because many strains are resistant to multiple class of antifungal drugs. The lack of available antifungals and rapid increase of this fungal pathogen provides an incentive...
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O07 Filaggrin insufficiency renders keratinocyte-derived small extracellular vesicles capable of affecting CD1a-mediated T-cell responses and promoting allergic inflammation
PublicationThe association between FLG loss-of-function mutations and the development of atopic dermatitis (AD) indicates that filaggrin is critical to skin barrier function; the mutations are also linked to additional allergic manifestations, but it is unknown how the skin may influence inflammation in distant tissues. Here we investigated the impact of filaggrin insufficiency on keratinocyte-derived exosome-enriched small extracellular...
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High gain/bandwidth off‑chip antenna loaded with metamaterial unit‑cell impedance matching circuit for sub‑terahertz near‑field electronic systems
PublicationAn innovative off-chip antenna (OCA) is presented that exhibits high gain and efficiency performance at the terahertz (THz) band and has a wide operational bandwidth. The proposed OCA is implemented on stacked silicon layers and consists of an open circuit meandering line. It is shown that by loading the antenna with an array of subwavelength circular dielectric slots and terminating it with a metamaterial unit cell, its impedance...
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The Effect of Full-Cell Impregnation of Pine Wood (Pinus sylvestris L.) on Changes in Electrical Resistance and on the Accuracy of Moisture Content Measurement Using Resistance Meters
PublicationThe impact of the full-cell impregnation of pine wood was investigated with respect to changes in electrical resistance and the accuracy of moisture content measurement. This study compared the resistance of impregnated and untreated pine timber harvested from the northern part of Poland (Pomeranian region). The wood was impregnated by the vacuum-pressure method. The preservative (TANALITH E 3475) and coloring (TANATONE 3950) agents...
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Modulation of UDP-glucuronidation by acridinone antitumor agents C-1305 and C-1311 in HepG2 and HT29 cell lines, despite slight impact in noncellular systems.
PublicationBackground Among the studied antitumor acridinone derivatives developed in our laboratory, 5-dimethylaminopropylamino-8-hydroxytriazoloacridinone (C-1305) and 5-diethylaminoethylamino-8-hydroxyimidazoacridinone (C-1311) exhibited cytotoxic and antitumor properties against several cancer types and were selected to be evaluated in preclinical and early-phase clinical trials. In the present work, we investigated the impact of C-1305...
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Synthesis of green benzamide-decorated UiO-66-NH2 for biomedical applications
PublicationMetal-organic frameworks (MOFs) biocompatible systems can host enzymes/bacteria/viruses. Herein we synthesized a series of fatty acid amide hydrolase (FAAH)-decorated UiO-66-NH2 based on Citrus tangerine leaf extract for drug delivery and biosensor applications. Five chemically manipulated FAAH-like benzamides were localized on the UiO-66-NH2 surface with physical interactions. Comprehensive cellular and molecular analyses were...
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How to influence the mesenchymal stem cells fate? Emerging role of ectoenzymes metabolizing nucleotides
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Apoptosis induction in C32 human melanoma cells by Jasione montana and its main phytoconstituents
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Detection of circulating tumor cells by means of machine learning using Smart-Seq2 sequencing
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Re-use of photovotaic [i.e. photovoltaic] crystalline silicon solar cells - technological possibilities
PublicationSystemy fotowoltaiczne są stosowane na całym świecie jako niezawodne i wydajne układy zasilania dla zastosowań przemysłowych, komunalnych i komercyjnych. Średni czas eksploatacji modułów fotowoltaicznych wynosi ponad 25 lat. Wyeksploatowane moduły oraz te, które uległy uszkodzeniu, są obecnie przeważnie składowane na wysypiskach jako odpady przemysłowe lub komunalne, np. jako szkło lub materiał rozbiórkowy, co było dopuszczalne...
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Określanie topologii sieci w celu lokalizacji abonenta telefonii VoIP wzywającego pomocy
PublicationTechnologia VoIP zaczyna odgrywać coraz większą rolę na rynku telekomunikacyjnym. W pracy przedstawiono problemy wdrażania w UE numeru alarmowego 112. Ważnym, nierozwiązanym problemem jest lokalizacja abonenta telefonii VoIP wzywającego pomocy. Przedstawiono problemy związane z wykrywaniem miejsca podłączenia telefonu VoIP w sieci Internet. Omówiono możliwości jakie stwarza w tym zakresie nowy protokół LLDP MED i porównano z innymi...
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Aggressive Phenotype of Cells Disseminated via Hematogenous and Lymphatic Route in Breast Cancer Patients
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Lipid mediators involved in the oxidative stress and antioxidant defence of human lung cancer cells
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Ultrastructural study of neoplastic cells in Macoma balthica (Bivalvia) from the Gulf of Gdansk (Poland).
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CYP3A4 overexpression enhances the cytotoxicity of the antitumor triazoloacridinone derivative C-1305 in CHO cells
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Analysis of Emission Factors in RDE Tests As Well as in NEDC and WLTC Chassis Dynamometer Tests
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Sulforaphene, an isothiocyanate present in radish plants, inhibits proliferation of human breast cancer cells
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The simultaneous detection of food dyes from different samples in a 96-well plate by spectrophotometry
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IL-22 modulates inflammatory properties of human primary aortic smooth muscle cells
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Spectroscopic Signature of Red Blood Cells in a D-Galactose-Induced Accelerated Aging Model
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Effect of GO-Fe3O4 and rotating magnetic field on cellular metabolic activity of mammalian cells
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Cation-ordered perovskite-type anode and cathode materials for solid oxide fuel cells
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Proteomic profiling of exosomes derived from pancreatic beta-cells cultured under hyperglycemia
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Well-Designed Porous Graphene Flakes for Lithium-Ion Batteries with Outstanding Rate Performance
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Similarities and Differences in the Protein Composition of Cutaneous Melanoma Cells and Their Exosomes Identified by Mass Spectrometry
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Graphene-encapsulated iron nanoparticles as a non-viral vector for gene delivery into melanoma cells
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1/f noise as a diagnostic tool for non-destructive testing of silicon solar cells
PublicationPrzeprowadzono badania eksperymentalne charakterystyk statycznych i szumowych krzemowych ogniw słonecznych. Wyniki wykazują możliwość wykorzystania szumu 1/f jako narzędzia diagnostycznego w testach nieniszczacych tych przyrzadów.
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Ocena języków systemów ekspertowych dla celu implementacji baz wiedzy Systemu Wieloagentowego
PublicationW pracy dokonano oceny wybranych narzędzi do implementacji modelu baz wiedzy systemu wieloagentowego do oceny technologii informatycznych. Narzędzia te to języki programowania systemów ekspertowych. Jakkolwiek bardzo dobrze sprawdzają się one w zastosowaniach związanych z gromadzeniem wiedzy w postaci zarówno faktów, jak i reguł to może się okazać, że nie udaje się z ich wykorzystaniem zrealizować wszystkich wymagań zdefiniowanych...
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MIX2: A Novel Natural Multi-Component Modulator of Multidrug-Resistance and Hallmarks of Cancer Cells
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Cele życiowe młodzieży kończącej szkołę podstawową. Próba klasyfikacji wartości młodego pokolenia
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The modulatory effect of green tea catechin on drug resistance in human ovarian cancer cells
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Synthesis of New Hydrazone Derivatives and Evaluation of their Efficacy as Proliferation Inhibitors in Human Cancer Cells
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Anticancer properties of ester derivatives of betulin in human metastatic melanoma cells (Me-45)
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Comparison of different digestion methods for proteomic analysis of isolated cells and FFPE tissue samples
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Evaluating the Role of Circulating Dendritic Cells in Methimazole-Treated Pediatric Graves’ Disease Patients
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Regulatory B Cells Involvement in Autoimmune Phenomena Occurring in Pediatric Graves’ Disease Patients
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Evaluating the Role of Circulating Dendritic Cells in Methimazole-Treated Pediatric Graves’ Disease Patients
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Investigations of New Phenothiazine-Based Compounds for Dye-Sensitized Solar Cells with Theoretical Insight
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Effect of thienyl units in cyanoacrylic acid derivatives toward dye-sensitized solar cells
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Nongeminate recombination in organic bulk heterojunction solar cells: Contribution of exciton–polaron interaction
PublicationA new model to explain nongeminate recombination in organic bulk heterojunction solar cells is presented. We suggest that the annihilation of excitons on charge carriers at the interface between donor and acceptor phases competes with the bimolecular recombination of Coulombically bound electron–hole pairs. The exciton–polaron interaction gives visible contribution to the reduction of Langevin recombination. An analytical formula,...
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Synthesis of novel dinuclear ruthenium polypyridine dye for dye-sensitized solar cells application
PublicationA new dinuclear ruthenium(II) polypyridine complex has been successfully synthesized. The new compound has been characterized by spectroscopic and electrochemical methods. Its potential application as a sensitizing dye in dye-sensitized solar cells has been checked under AM 1.5 G irradiation conditions (100 mW cm−2) and its performance was compared to that of a commercially available mononuclear analogous dye. The overall light-to-electricity...
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Badanie zastosowania geolokalizacji w celu budowania relacji z klientami – analiza przypadku
PublicationCel. Zastosowanie geolokalizacji w biznesie staje się coraz bardziej powszechne, a zasięg technik geomarketingu zwiększa się wraz z rozwojem technologii mobilnej. Czynniki te sprawiają, że przedsiębiorcy coraz częściej sięgają po metody geolokalizacyjne przy prowadzeniu działalności, wspomagając działania operacyjne i promocyjne. Celem pracy była wstępna weryfikacja możliwości i efektywności zastosowania systemów...
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Usługi Third Party Call Control zrealizowane z wykorzystaniem oprogramowania Open Source
PublicationKoncepcja sieci NGN zakłada otwartość na usługi udostępniane użytkownikom (abonentom). Jej realizacja wymaga ulokowania tej funkcjonalności w zewnętrznych elementach w stosunku do sieci telekomunikacyjnej udostępniającej usługi przenoszenia. Jednym z rozwiązań jest serwer Third Party Call Control (3PCC) w którym można ulokować scenariusze sterowania przebiegiem połączenia. W artykule przedstawiono i omówiono projekt, wykonany w...