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Search results for: KOMPOZYTY MEDYCZNE
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Peroxidative metabolism of arachidonic acid in the course of Lyme arthritis
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Peroxidative metabolism of fatty acids in the course of tick-borne encephalitis
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The cross talk between redox and endocannabinoids systems in the kidney of hypertensive rats after inhibitor FAAH - URB597 administration
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Antioxidants and HNE in the regulation of redox homeostasis
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Lipid peroxidation as a consequence of diabetes: effects of different treatment
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Lipid peroxidation in the pathogenesis of neuroborreliosis
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Does Eccentric-only and Concentric-only Activation Increase Power Output?
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Institution of the health care agent in Polish legislation: position of the Polish Working Group on End-of-Life Ethics
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Shape-Depended Biological Properties of Ag3PO4 Microparticles: Evaluation of Antimicrobial Properties and Cytotoxicity in In Vitro Model—Safety Assessment of Potential Clinical Usage
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Stickstoffbilanz bei Patienten nach laparoskopischer Cholezystektomie
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The influence of statin monotherapy and statin-ezetimibe combined therapy on FoxP3 and IL 10 mRNA expression in patients with coronary artery disease
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Severe hypodysfibrinogenemia in a young patient with pulmonary thromboembolism: a case report
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Primary splenic angiosarcoma: a very rare and aggressive neoplasm with a poor prognosis
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Assessment of the mean time in the therapeutic INR range and the SAME-TT2R2 score in patients with atrial fibrillation and cognitive impairment
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IL-22 modulates inflammatory properties of human primary aortic smooth muscle cells
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Modeling the photodynamic effect in 2D versus 3D cell culture under normoxic and hypoxic conditions
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Cerebral tissue oxygenation during cranial osteopathic CV4 procedure in newborns
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Patient rights, risk, and responsibilities in the genetic era – a right to know, a right not to know, or a duty to know?
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Nighttime Hypoglycemia in Children with Type 1 Diabetes after one Day of Football Tournament
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Expression of ghrelin and ghrelin functional receptor GHSR1a in human pituitary adenomas
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Bleeding in anticoagulated patients with atrial fibrillation: practical considerations
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Stage of liver fibrosis in patients with congenital bleeding disorders and infected with hepatitis C virus
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Quality of life in long-term survivors of early stage endometrial cancer
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Risk factors for chronic kidney disease do not influence the serum levels of asymmetric dimethylarginine in HIV-1-infected patients without significant renal disease
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An unusual case of gastrointestinal obstruction caused by bladder enlargement
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Biological and psychological components of depression in patients receiving IFN-alpha therapy for hepatitis C
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A rare cause of nontraumatic ureter perforation
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α-Lipoic Acid Strengthens the Antioxidant Barrier and Reduces Oxidative, Nitrosative, and Glycative Damage, as well as Inhibits Inflammation and Apoptosis in the Hypothalamus but Not in the Cerebral Cortex of Insulin-Resistant Rats
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The impact of cytogenetic evolution and acquisition of del(17p) on the prognosis of multiple myeloma patients
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Safe administration of rituximab in patients with chronic lymphocytic leukemia and a history of obinutuzumab‑associated anaphylaxis
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A new potential mode of cardiorenal protection of KLOTHO gene variability in type 1 diabetic adolescents
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The clinician’s guide to radiotherapy complications
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Effect of increased protein intake on the risk of female infertility
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Antibody reactivity in patients with IgE-mediated wheat allergy to various subunits and fractions of gluten and non-gluten proteins from ω-gliadin-free wheat genotypes
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The role of environmental optimization for storing bulls’ sperm cells
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Wearable Cardioverter–Defibrillator after Myocardial Infarction
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Central nervous system prophylaxis with intrathecal liposomal cytarabine in diffuse large B‑cell lymphomas
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Efficacy and safety of the obinutuzumab-chlorambucil combination in the frontline treatment of elderly CLL patients with comorbidities – Polish Adult Leukemia Group (PALG) real-life analysis
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Gemcitabine-Based Treatment in Poor Prognosis Patients with Relapsed and Refractory Hodgkin Lymphoma and Non-Hodgkin Lymphoma – a Multicenter Polish Experience
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PI3Kδ Inhibition by Idelalisib in Patients with Relapsed Indolent Lymphoma
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Role of rituximab in the first-line therapy of high-risk diffuse large B-cell lymphoma: a retrospective analysis by the Polish Lymphoma Research Group
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Targeting BTK with Ibrutinib in Relapsed or Refractory Mantle-Cell Lymphoma
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Brentuximab Vedotin with Chemotherapy for Stage III or IV Hodgkin’s Lymphoma
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Antimicrobial molecular nanocarrier–drug conjugates
PublicationMany antimicrobial drugs are poorly active against pathogenic microbes causing intracellular infections, such as Mycobacterium tuberculosis or Plasmodium falciparum. On the other hand, several known antimicrobial agents are not effective enough because of their limited cellular penetration. A common feature of both challenges is the inability of an active agent to cross the biological membrane(s). One of the possible approaches...
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Basic Hand Gestures Classification Based on Surface Electromyography
PublicationThis paper presents an innovative classification system for hand gestures using 2-channel surface electromyography analysis. The system developed uses the Support Vector Machine classifier, for which the kernel function and parameter optimisation are conducted additionally by the Cuckoo Search swarm algorithm. The system developed is compared with standard Support Vector Machine classifiers with various kernel functions. The average...
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Influence of Diosmin Treatment on the Level of Oxidative Stress Markers in Patients with Chronic Venous Insufficiency
PublicationOxidative stress plays an important role in the pathophysiology of many human disorders, while antioxidants prevent the development of various adverse symptoms. Diosmin is a natural flavonoid applied in vascular system disorders, especially in chronic venous insufficiency (CVI), and it plays a significant part in the alleviation of CVI symptoms. Due to antioxidant activity, it also has the ability to scavenge the oxygen free radicals...
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Telomere uncapping by common oxidative guanine lesions: Insights from atomistic models
PublicationOxidative damage to DNA is widely known to contribute to aging and disease. This relationship has been extensively studied for telomeres – structures that cap chromosome ends – due to their role in cell proliferation and senescence, and exceptional susceptibility to oxidation. Indeed, the repetitive telomeric DNA sequence contains the 5′-GGG-3′ motif that has the lowest ionization potential of all trinucleotides. Accordingly, experiments...
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Interactions between bioactive components determine antioxidant, cytotoxic and nutrigenomic activity of cocoa powder extract
PublicationNumerous studies have shown, rather disappointingly, that isolated bioactive phytochemicals are not as biologically effective as natural plant products. Such a discrepancy may be explained by the concept of food synergy, which was verified in this research for cocoa extract versus its major components with regard to cancer chemoprevention. The evaluation embraced the relationship between redox properties evaluated in cell-free systems...
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Coupling of Blood Pressure and Subarachnoid Space Oscillations at Cardiac Frequency Evoked by Handgrip and Cold Tests: A Bispectral Analysis
PublicationThe aim of the study was to assess blood pressure–subarachnoid space (BP–SAS) width coupling properties using time–frequency bispectral analysis based on wavelet transforms during handgrip and cold tests. The experiments were performed on a group of 16 healthy subjects (F/M; 7/9) of the mean age 27.2 ± 6.8 years and body mass index of 23.8 ± 4.1 kg/m². The sequence of challenges was first handgrip and then cold test. The handgrip...
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Daily diet containing canned products significantly increases serum concentrations of endocrine disruptor bisphenol A in young women
PublicationNowadays, exposure to environmental factors is considered to be one of the possible causes of several lifestyle diseases, such as obesity, type 2 diabetes, cardiovascular disease, and cancer. Particularly noteworthy are endocrine‑disrupting chemicals (EDCs), which affect the metabolism of hormones and interact with their receptors, thus exerting adverse health effects. One of the most ubiquitous EDC in daily life is bisphenol A...