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Search results for: PANCREATIC CANCER
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Comparison of Pteridine Normalization Methods in Urine for Detection of Bladder Cancer
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The Role of miRNA-7 in the Biology of Cancer and Modulation of Drug Resistance
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Diamond Nanofilm Normalizes Proliferation and Metabolism in Liver Cancer Cells
PublicationPurpose: Surgical resection of hepatocellular carcinoma can be associated with recurrence resulting from the degeneration of residual volume of the liver. The objective was to assess the possibility of using a biocompatible nanofilm, made of a colloid of diamond nanoparticles (nfND), to fill the side after tumour resection and optimize its contact with proliferating liver cells, minimizing their cancerous transformation. Methods:...
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Microbiota-derived metabolites in colorectal cancer patients in preoperative period
PublicationShort-chain fat-ty acids (SCFAs) are microbial derived metabo-lites, which have multiple beneficial properties. The amount of SCFAs depends on several fac-tors, such as age, diet (mainly intake of dietary fiber), and overall health condition. The normal proportion between SCFAs is 3:1:1 for acetate, proprionate and butyrate, respectively. In col-orectal cancer (CRC) patients, microbiota alter-ations have been shown. Consequently,...
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Folate/homocysteine metabolism and lung cancer risk among smokers
PublicationBackground: Folate and homocysteine are involved in DNA synthesis and methylation processes, which are deregulated during carcinogenesis. Objectives: The aim of this study was to assess the relationship between folate/homocysteine concentrations, the functional polymorphisms of folate/homocysteine genes and lung cancer risk among cigarette smokers. Study design: The study included 132 lung cancer patients and 396 controls from...
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Effect of in vitro gastro‐pancreatic digestion on antioxidant activity of low‐molecular‐weight (<3.5 kDa) peptides from dry‐cured pork loins with probiotic strains of LAB
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Stage I non-small-cell lung cancer: long-term results of lobectomy versus sublobar resection from the Polish National Lung Cancer Registry†
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New Unsymmetrical Bisacridine Derivatives Noncovalently Attached to Quaternary Quantum Dots Improve Cancer Therapy by Enhancing Cytotoxicity toward Cancer Cells and Protecting Normal Cells
PublicationThe use of nanoparticles for the controlled drug delivery to cells has emerged as a good alternative to traditional systemic delivery. Quantum dots (QDs) offer potentially invaluable societal benefits such as drug targeting and in vivo biomedical imaging. In contrast, QDs may also pose risks to human health and the environment under certain conditions. Here, we demonstrated that unique combination of nanocrystals core components...
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Volumetric staging in radiotherapy for oropharyngeal cancers
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Pregnancy-associated Cancers: A Narrative Review
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Cadmium, arsenic, selenium and iron– Implications for tumor progression in breast cancer
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Metachronous adenocarcinoma in a gastric tube after radical surgery for oesophageal cancer
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The rs1447295 and DG8S737 markers on chromosome 8q24 and cancer risk in the Polish population
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A common nonsense mutation of the BLM gene and prostate cancer risk and survival
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MC1R common variants, CDKN2A and their association with melanoma and breast cancer risk
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Breast Cancer Heterogeneity Investigation: Multiple k-Means Clustering Approach
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Molecular Profiling for Predictors of Radiosensitivity in Patients with Breast or Head-and-Neck Cancer
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Erratum to: Sulforaphane inhibits growth of phenotypically different breast cancer cells
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Radiation-Induced Changes in Serum Lipidome of Head and Neck Cancer Patients
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cDNA sequencing improves the detection of P53 missense mutations in colorectal cancer
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Mixture model of NMR - its application to diagnosis and treatment of brain cancer
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Severe oxidatively damaged DNA after cisplatin treatment of cancer patients
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Oxidative DNA damage in cancer patients: a cause or a consequence of the disease development?
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K-ras gene mutation as an early prognostic marker of colon cancer
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Myotilin, a New Topotecan Resistant Protein in Ovarian Cancer Cell Lines
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The significance of lumican expression in ovarian cancer drug-resistant cell lines
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Diagnostic potential for a serum miRNA neural network for detection of ovarian cancer
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Inhibition of protein glycosylation reverses the MDR phenotype of cancer cell lines
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Pharmacokinetics and pharmacodynamics of propofol in cancer patients undergoing major lung surgery
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Quality of life in long-term survivors of early stage endometrial cancer
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Clinical Implications of mTOR Expression in Papillary Thyroid Cancer—A Systematic Review
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H2AX phosphorylation, its role in DNA damage response and cancer therapy
PublicationDouble-strand breaks (DSBs) are the most deleterious DNA lesions, which, if left unrepaired, may have severe consequences for cell survival, as they lead to chromosome aberrations, genomic instability, or cell death. Various physical, chemical, and biological factors are involved in DSB induction. Cells respond to DNA damage by activating the so-called DNA damage response (DDR), a complex molecular mechanism developed to detect...
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Inhibitory mikrotubul w terapii przeciwnowotworowej = Inhibitors of microtubule in cancer therapy
PublicationW artykule opisano inhibitory mikrotubul, różnorodne związki chemiczne, znajdujące się w zaawansowanych przedklinicznych i wstępnych badaniach klinicznych. Pośród nich na uwagę zasługują półsyntetyczne analogi taksolu, substancje pochodzenia naturalnego, takie jak: epotilony, kombretastatyny, kolchinoidy, dolastatyny oraz syntetyczne związki o niskim ciężarze czasteczkowym: heterokombretastatyny, sulfonamidy, fenostatyny, pochodne...
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Influence of Transurethral Resection of Bladder Cancer on Sexual Function, Anxiety, and Depression
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New data on antihypertensive drugs and risk of cancer: should we worry?
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Urinary metabolomic signature of muscle-invasive bladder cancer: A multiplatform approach
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The Influence of The Light-Activated Titania P25 on Human Breast Cancer Cells
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Assestment of the anti-cancer activity of the copper complexes with imidazole and pivalato ligands
PublicationDespite the development of science and technology progress so far there have not been found effective drugs for cancer. Many coordination compounds were investigated due to their antitumor potential. The most known cis-diamminedichloroplatinum(II) is used as anti-cancer therapeutic agent. The copper complexes are the coordination compounds possessing anti-tumour properties. Their capability to kill cancer cells is mainly linked...
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Growth inhibition of cultured cancer cells by Ribes nigrum leaf extract
PublicationThe present article includes data on the possible selective cytotoxic effect of extract of Ribes nigrum L. growing at high Armenian landscape. For this purpose, different non-cancer (microglial BV-2 wild type (Wt), acyl-CoA oxidase 1 (ACOX1) deficient (Acox1-/-) and cancer (human colon adenocarcinoma HT29 and human breast cancer MCF7) cell lines were applied. R. nigrum leaf ethanol extract showed a growth inhibition effect towards...
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Predictions of cervical cancer identification by photonic method combined with machine learning
PublicationCervical cancer is one of the most commonly appearing cancers, which early diagnosis is of greatest importance. Unfortunately, many diagnoses are based on subjective opinions of doctors—to date, there is no general measurement method with a calibrated standard. The problem can be solved with the measurement system being a fusion of an optoelectronic sensor and machine learning algorithm to provide reliable assistance for doctors...
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The Influence of Antitumor Unsymmetrical Bisacridines on 3D Cancer Spheroids Growth and Viability
PublicationThe culture of 3D spheroids is a promising tool in drug development and testing. Recently, we synthesized a new group of compounds, unsymmetrical bisacridines (UAs), which exhibit high cytotoxicity against various human cell lines and antitumor potency against several xenografts. Here, we describe the ability of four UAs—C-2028, C-2041, C-2045, and C-2053—to influence the growth of HCT116 and H460 spheres and the viability of HCT116...
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RAGE as a Novel Biomarker for Prostate Cancer: A Systematic Review and Meta-Analysis
PublicationThe receptor for advanced glycation end-products (RAGE) has been implicated in driving prostate cancer (PCa) growth, aggression, and metastasis through the fueling of chronic inflammation in the tumor microenvironment. This systematic review and meta-analysis summarizes and analyzes the current clinical and preclinical data to provide insight into the relationships among RAGE levels and PCa, cancer grade, and molecular effects....
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Insights into oral microbiome and colorectal cancer – on the way of searching new perspectives
PublicationMicrobiome is a keystone polymicrobial community that coexist with human body in a beneficial relationship. These microorganisms enable the human body to maintain homeostasis and take part in mechanisms of defense against infection and in the absorption of nutrients. Even though microbiome is involved in physiologic processes that are beneficial to host health, it may also cause serious detrimental issues. Additionally, it has been...
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Differential Response of MDA-MB-231 and MCF-7 Breast Cancer Cells to In Vitro Inhibition with CTLA-4 and PD-1 through Cancer-Immune Cells Modified Interactions
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Altered circadian genes expression in breast cancer tissue according to the clinical characteristics
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The impact of the Polish mass breast cancer screening program on prognosis in the Pomeranian Province
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Prognostic Significance of TOP2A Gene Dosage in HER-2-Negative Breast Cancer
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CDKN2A common variant and multi-organ cancer risk—a population-based study
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Therapy with CD4+CD25+ T regulatory cells – should we be afraid of cancer?
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Germline mutations in theCHEK2 kinase gene are associated with an increased risk of bladder cancer
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