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Catalog Publications

Year 2022
  • Straightened characteristics of McKendrick-von Foerster equation
    Publication

    - JOURNAL OF DIFFERENTIAL EQUATIONS - Year 2022

    We study the McKendrick-von Foerster equation with renewal (that is the age-structured model, with total population dependent coefficient and nonlinearity). By using a change of variables, the model is then transformed to a standard age-structured model in which the total population dependent coefficient of the transport term reduces to a constant 1. We use this transformation to get existence, uniqueness of solutions of the problem...

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  • t-SNE Highlights Phylogenetic and Temporal Patterns of SARS-CoV-2 Spike and Nucleocapsid Protein Evolution
    Publication
    • G. Tamazian
    • A. Komissarov
    • D. Kobak
    • D. Polyakov
    • E. Andronov
    • S. Nechaev
    • S. Kryzhevich
    • Y. Porozov
    • E. Stepanov

    - Year 2022

    We propose applying t-distributed stochastic neighbor embedding to protein sequences of SARS-CoV-2 to construct, visualize and study the evolutionary space of the coronavirus. The basic idea is to explore the COVID-19 evolution space by using modern manifold learning techniques applied to evolutionary distances between variants. Evolutionary distances have been calculated based on the structures of the nucleocapsid and spike proteins.

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