Wyszukiwarka
Structural changes of bacterial cellulose due to incubation in conditions simulating human plasma in the presence of selected pathogens
Abstrakt
Bacterial nanocellulose (BNC) is a natural biomaterial with a wide range of medical applications. However, it cannot be used as a biological implant of the circulatory system without checking whether it is biodegradable under human plasma conditions. This work aimed to investigate the BNC biodegradation by selected pathogens under conditions simulating human plasma. The BNC was incubated in simulated biological fluids with or without Staphylococcus aureus, Candida albicans and Aspergillus fumigatus, and its physicochemical properties were studied. The results showed that the incubation of BNC in simulated body fluid with A. fumigatus con-tributes more to its degradation than that under other conditions tested. The rearrangement of the hydrogen- bond network in this case resulted in a more compact structure, with an increased crystallinity index, reduced thermal stability and looser cross-linking. Therefore, although BNC shows great potential as a cardiovascular implant material, before use for this purpose its biodegradability should be limited.
Cytowania
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2
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0
Web of Science
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2
Scopus
Autorzy (3)
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Paulina Dederko-Kantowicz
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Pełna treść
- Wersja publikacji
- Accepted albo Published Version
- Licencja
-
otwiera się w nowej karcie
Słowa kluczowe
Informacje szczegółowe
- Kategoria:
- Publikacja w czasopiśmie
- Typ:
- artykuły w czasopismach
- Opublikowano w:
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CARBOHYDRATE POLYMERS
nr 266,
ISSN: 0144-8617 - Język:
- angielski
- Rok wydania:
- 2021
- Opis bibliograficzny:
- Dederko-Kantowicz P., Sommer A., Staroszczyk H.: Structural changes of bacterial cellulose due to incubation in conditions simulating human plasma in the presence of selected pathogens// CARBOHYDRATE POLYMERS -Vol. 266, (2021), s.118153-
- DOI:
- Cyfrowy identyfikator dokumentu elektronicznego (otwiera się w nowej karcie) 10.1016/j.carbpol.2021.118153
- Źródła finansowania:
-
- IDUB
- Weryfikacja:
- Politechnika Gdańska
wyświetlono 145 razy
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